Purine nucleosides
Medchemexpress LLC Deoxyguanosine triphosphate trisodium solution | 93919-41-6 | 99.95% | 573.13 | 28.66 MG
Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. It is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification. Deoxyguanosine triphosphate is abnormally elevated in the red blood cells of individuals with immunodeficiency related to purine nucleoside phosphorylase deficiency, and it can be regarded as a potential toxic metabolite.
- Nucleotide precursor for DNA synthesis.
- Used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
Medchemexpress LLC 2'-deoxyadenosine-5'-monophosphate-d12 dilithium | 97.7% | 355.16 | C10D12Li2N5O6P | 1 MG
2'-Deoxyadenosine-5'-monophosphate-d12 (dilithium) is a deuterium-labeled form of 2'-deoxyadenosine-5'-monophosphate used as a research reagent to study DNA synthesis, nucleotide interactions, and isotope tracing by mass spectrometry or NMR. Supplied as the dilithium salt, it is intended for laboratory research use only.
- Isotopically labeled d12 for accurate mass-shift studies.
- Suitable for mass spectrometry and NMR applications.
- Dilithium salt form for improved solubility in selected buffers.
- High purity (97.7%) for reproducible experimental results.
- Compatible with nucleotide chemistry and DNA interaction studies.
Cambridge Isotope Laboratories 2-Deoxyadenosine 5-triphosphate ammonium salt (13C10 98% 15N5 96-98%) CP 90% (in solution) 20 umol
2-Deoxyadenosine 5-triphosphate ammonium salt (13C10 98% 15N5 96-98%) CP 90% (in solution) 20 umol
Medchemexpress LLC Adenosine, 8-bromo-2'-deoxy- | 14985-44-5 | ≥98.0% | 330.14 | 10 MM 1 ML
8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Cayman Chemical N6-benzoyl-2-DeoxyadenosIn 5g
A nucleoside building block; has been used in the synthesis of various oligonucleotides
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.9% | 269.26 | 25 G
2'-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. It also inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation, activates caspase-3, promotes apoptosis, inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH), and inhibits the growth of various cells, demonstrating an anticancer effect on colon cancer.
- Inhibits glucose-stimulated insulin release.
- Inhibits glucose-stimulated increases in islet cyclic AMP accumulation.
- Activates caspase-3 and promotes apoptosis.
- Inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH).
- Inhibits the growth of various cells.
- Has an anticancer effect on colon cancer.
- Appears as a solid, white to off-white substance.
- Initial source is microorganisms (Streptomyces jiujiangensis).
Cayman Chemical 5-chloro-5-DeoxyadenosIn 10g
A nucleoside analog used as a substrate in the biosynthesis of the anticancer agent salinosporamide A
Medchemexpress LLC N6-Threonylcarbamoyladenosine | 24719-82-2 | 99.6% | 412.35 | 1 MG
N6-Threonylcarbamoyladenosine is a common nucleoside that can decorate and become tRNA. It is for research use only.
- Purity of 99.62%
- Molecular weight of 412.35
- Chemical formula: C15H20N6O8
- Appearance: Solid
- Color: Off-white to light brown
- Storage conditions: -20°C for powder, -80°C for 6 months in solvent
Medchemexpress LLC 2-Deoxyadenosine 5 250mg
2 -Deoxyadenosine 5 -monophosphate disodium a nucleic acid AMP derivative is a deoxyribonucleotide found in DNA 2 -Deoxyadenosine 5 -monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1]
Medchemexpress LLC Malvidin-3-O-arabinoside chloride | 28500-04-1 | 97.10% | 498.86 | 1 MG
Malvidin-3-O-arabinoside chloride ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. It upregulates LAMP-1 expression, restores lysosomal acidity, strengthens lysosomal functions, and stimulates phosphorylation of AMP-activated protein kinase (AMPK).
- Upregulates LAMP-1 expression
- Restores lysosomal acidity
- Strengthens lysosomal functions
- Stimulates phosphorylation of AMP-activated protein kinase (AMPK)
- Inhibits excess ROS generation
- Enhances GSH level
- Enhances autophagy flux
- Up-regulates the LC3-II/LC3-I ratio
Cayman Chemical N6-benzoyl-2-DeoxyadenosIn 1g
A nucleoside building block; has been used in the synthesis of various oligonucleotides
Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 1mg
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Medchemexpress LLC 2'-Deoxyguanosine-13C10,15N5 monohydrate | 2483830-26-6 | 99.8% | 1 MG
2'-Deoxyguanosine-13C10,15N5 (monohydrate) is the 13C and 15N labeled 2'-Deoxyguanosine monohydrate, which is an endogenous metabolite. It is for research use only and not sold to patients.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for quantitation during the drug development process.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 2'-deoxyadenosine | 958-09-8 | MFCD00005754 | 99.9% | 251.24 g/mol | C10H13N5O3 | 1 ML
2'-deoxyadenosine solution (10 mM in DMSO, 1 mL) is an adenine nucleoside supplied as a ready-to-use research solution intended for biochemical and analytical applications. It is commonly used as an analytical standard and in studies of nucleoside metabolism, apoptosis, and cell growth inhibition.
- Ready-to-use 10 mM solution in DMSO.
- Net volume: 1 mL.
- Intended for research and analytical applications.
- Used in studies of nucleoside metabolism, insulin secretion, and apoptosis.
- High purity reported for the solid standard (99.94%).