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Motesanib diphosphate is the diphosphate salt of a small-molecule ATP-competitive inhibitor of vascular endothelial growth factor receptors (VEGFR1/2/3). It is supplied as a research-grade analytical standard for biochemical assays, pathway studies, and method development. The compound should be stored sealed and protected from moisture; in solvent, stability is -80°C for up to six months and -20°C for up to one month.
High purity (~99.9%).
Potent VEGFR1/2/3 inhibition with IC50s 2-6 nM.
Molecular formula C22H29N5O9P2, molecular weight 569.44 g/mol.
Suitable for biochemical assays and analytical method development.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
8-Azido-ATP is a ribonucleoside triphosphate analog with an azido group substitution at the adenine C-8 position It acts primarily as an ATP mimic interacting with poly(A) polymerase (PAP) specifically illustrated using yeast poly(A) polymerase (yPAP) Incorporation of 8-azido-ATP into growing polyadenylation chains results in premature termination and moderately shorter poly(A) tails relative to natural ATP substrates Due to its chain-terminating capacity and altered substrate specificity 8-azido-ATP is applied in biochemical studies examining enzyme fidelity nucleotide selection mechanisms and RNA polymerase activity
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More