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Two-carbon nitrogen ring bases (adenine and guanine) covalently linked to a sugar (ribose or deoxyribose) and one to three phosphate groups; can function as extracellular messengers, antimetabolites, and chain terminators that inhibit viral DNA polymerase.
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Adenosine 5'-triphosphate (ATP) standard supplied as a 10 mg solid for analytical and research use. It is intended as a calibration and reference material for quantitation of ATP in biochemical assays, metabolic studies, and signaling research.
Analytical reference standard for ATP quantitation.
High purity: 95.7%.
White to off-white solid suitable for dissolution in aqueous buffers.
Useful for assay calibration, method development, and quality control.
Includes CAS number 56-65-5 for clear substance identification.
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BRM/BRG1 ATP Inhibitor-2 is a BRG1/BRM ATPase inhibitor used for the research of BAF-related disorders. It is intended for research use only and is not sold to patients. The compound has a molecular weight of 412.53 and appears as a white to off-white solid. It is soluble in DMSO at 100 mg/mL.
Used for the research of BAF-related disorders
Appears as a white to off-white solid
Soluble in DMSO at 100 mg/mL
Stock solutions can be stored at -80°C for 6 months or -20°C for 1 month
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Adenosine receptor antagonist 4 is a small-molecule research compound that antagonizes the human adenosine A1 receptor, with a reported Ki of 101 nM. It is supplied as a solid and is intended for in vitro pharmacology and receptor-binding studies.
Acts as an adenosine A1 receptor antagonist (Ki ≈ 101 nM).
Molecular formula C10H13N3 and molecular weight ≈ 175.24 g·mol^-1.
High purity as reported in batch COA (≈99.35%).
Appearance: solid; recommended storage conditions vary by form (room temperature for solid; -80°C in solution).
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GTP-14564 is a tyrosine kinase inhibitor targeting internal tandem duplication (ITD) and FLT3, which inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
Targets internal tandem duplication (ITD) and FLT3.
Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
Used in cancer targeted therapy.
Functions as an inhibitor of Fms-like tyrosine kinase 3 (FLT3).
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Alpha-Guanosine is a purine nucleoside analog that exhibits broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
Purine nucleoside analog
Exhibits broad antitumor activity
Targets indolent lymphoid malignancies
Inhibits DNA synthesis
Induces apoptosis
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Adenosine 5'-triphosphate(ATP)-d4 (ammonium salt) is the deuterium labeled Adenosine 5'-triphosphate(ATP) ammonium salt. It is intended for research use only.
Can be used as a tracer
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Guanosine 5'-triphosphate trisodium salt hydrate is an activator of the signal transducing G proteins and serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
Activator of signal transducing G proteins
Energy-rich precursor in DNA and RNA biosynthesis
For research use only
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Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates the adenosine 5'-triphosphate-sensitive K+ channel. It acts as an iron mobilizer by forming a complex with hepcidin, inhibiting the hepcidin-ferroportin (FPN) interaction, and modulating the IL-6/stat-3 pathway. It has been shown to ameliorate Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO4 and can be used in AI research.
2p-O-Methyl-2-Amino-ATP is a modified nucleoside triphosphate incorporating methylation at the ribose 2 -hydroxyl group and an amino substitution at the 2 position of the adenine base It is designed to alter nucleotide biochemical properties impacting RNA stability and structure upon enzymatic incorporation In in vitro transcription assays 2p-O-Methyl-2-Amino-ATP demonstrates an ability to increase RNA resistance to exonuclease-mediated degradation and induce altered RNA secondary structures Based on these properties 2p-O-Methyl-2-Amino-ATP holds research potential in studies of RNA folding dynamics stability assays RNA-protein interactions and analyses involving chemically modified RNA in biomedical research
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2p-O-Methyl-N6-Methyl-ATP is a chemically modified ATP analog bearing methyl substitutions at the N6 position of adenine and the 2 -hydroxyl group of the ribose sugar 2p-O-Methyl-N6-Methyl-ATP is designed to facilitate the study of RNA methylation processes and RNA protein interactions supporting the mechanistic exploration of RNA-modifying enzymes and epigenetic regulatory pathways Based on these properties 2p-O-Methyl-N6-Methyl-ATP holds research potential in investigations of ligand RNA interactions and drug discovery applications targeting RNA-related biological processes
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AZT triphosphate tetraammonium is the tetraammonium salt of the active triphosphate metabolite of zidovudine (AZT). It is used as a biochemical reagent in virology and nucleotide metabolism studies where the active nucleotide analog is required. The product is supplied with a certificate of analysis and safety data sheet and is intended for research use only.
Active triphosphate metabolite of zidovudine (AZT) for biochemical assays.
High chemical purity suitable for analytical and cellular studies.
Available as a solid in multiple milligram sizes and as a 10 mM solution in DMSO.
Supplied with certificate of analysis and safety data sheet for quality and handling information.
Recommended storage: sealed at -20°C; in solvent store at -80°C for up to 6 months.
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ATP synthase inhibitor 1 is a potent inhibitor of the c subunit of the F1/FO-ATP synthase complex. It inhibits mitochondrial permeability transition pore (mPTP) opening but does not affect ATP levels.
Potent inhibitor of c subunit of the F1/FO-ATP synthase complex