Drug Standards

Selleck Chemical LLC Mitoxantrone 2HCl 10mM/1mL 70476-82-3 NSC-301739

Mitoxantrone 2HCl (NSC-301739) is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 ?M for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 ?M. Mitoxantrone also induces apoptosis. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

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Medchemexpress LLC Sabizabulin | 1332881-26-1 | 99.0% | 50 MG

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Sabizabulin (VERU-111; ABI-231) is a small-molecule tubulin inhibitor provided for research use. It disrupts microtubule dynamics and is commonly used in cellular assays and mechanism-of-action studies. Reported purity is 99.0% and the compound is available in multiple small-mass packaging options.

• Small-molecule tubulin inhibitor used in cellular and biochemical assays.
• Reported purity 99.0% for consistent experimental results.
• Available in small-mass packaging suitable for preclinical studies.
• Useful for mechanism-of-action and microtubule dynamics research.
• CAS number 1332881-26-1 for unambiguous identification.

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Cayman Chemical DIclofenac ethyl ester 25mg

An esterified form of diclofenac; has been used as a precursor in the synthesis of diclofenac derivatives with anti-inflammatory and analgesic activity and decreased ulcerogenicity

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Sigma Aldrich Fine Chemicals Biosciences Amoxicillin trihydrate British Pharmacopoeia (BP) Reference Standard | 61336-70-7 | MFCD00072029 |

Amoxicillin trihydrate British Pharmacopoeia (BP) Reference Standard | Mol Wt: 419.45 | 61336-70-7 | MFCD00072029 |

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Selleck Chemical LLC Resiquimod 20mg 144875-48-9 R-848

Resiquimod (R-848) is an immune response modifier that acts as a potent TLR 7/TLR 8 agonist that induces the upregulation of cytokines such as TNF-?, IL-6 and IFN-?. Resiquimod reduces hepatitis C virus (HCV) infection. Phase 2. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

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Medchemexpress LLC Mevastatin | 73573-88-3 | 99.46% | 390.51 | 100 MG

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Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor belonging to the statin class. It functions as a lipid-lowering agent and is known to induce apoptosis and arrest cancer cells in the G0/G1 phase. Additionally, Mevastatin increases endothelial nitric oxide synthase (eNOS) mRNA and protein levels. It exhibits antitumor activity and shows potential for the treatment of cardiovascular diseases.

• Primary inhibitor of HMG-CoA reductase
• Lipid-lowering agent
• Induces apoptosis
• Arrests cancer cells in the G0/G1 phase
• Increases eNOS mRNA and protein levels
• Exhibits antitumor activity
• Potential for cardiovascular disease treatment
• Initial source from Microorganisms (Penicillium citrinum)
• Solid, white to off-white appearance

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Selleck Chemical LLC Lanabecestat (AZD3293) 5mg 1383982-64-6 LY3314814

Lanabecestat (AZD3293, LY3314814) is an oral beta-secretase 1 cleaving enzyme (BACE) inhibitor with an inhibitory constant Ki? of 0.4 nM. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

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U.S. Pharmacopeia U S PHARMACOPEIA

NC4027463 VERAPAMIL RELTDCOMPOUND A 50MG

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Medchemexpress LLC 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)- | 147098-18-8 | 99.9% | 503.52 | 200 MG

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Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. It potently blocks hERG current with an IC50 of 195 nM. This compound effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

• Reduces the expression of mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein.
• Effectively lowers low-density lipoprotein (LDL) cholesterol.
• Reduces triglyceride levels.
• Decreases C-reactive protein levels.

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Medchemexpress LLC Capreomycin (sulfate) | 1405-37-4 | 99.5% | 1 G

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Capreomycin sulfate is a macrocyclic peptide antibiotic that inhibits phenylalanine synthesis in mycobacterial ribosomal translation. It exhibits anti-amyloidogenic and pro-fibrinolytic activities, reducing amyloid-induced cytotoxicity by inhibiting amyloid fibrillation. This product is suitable for studies related to multidrug-resistant tuberculosis, type 2 diabetes, Alzheimer's disease, and Parkinson's disease.

• Inhibits insulin fibril formation in human erythrocytes.
• Protects against amyloid fibril-induced erythrocyte damage and hemolysis.
• Destroys fibrils in erythrocytes in a time-dependent manner.
• Decreases wet lung weight and bacterial burden in the lungs of infected guinea pigs.
• Appearance: solid.
• Color: white to off-white.
• Initial source: microorganisms (Streptomyces capreolus).
• Storage: -20°C, sealed, away from moisture.
• Solubility in H2O: 100 mg/mL (requires ultrasonic).

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Selleck Chemical LLC Thiotepa S1775-10mM/1mL

Thiotepa (Thioplex Tiofosyl Tiofosfamid Triethylenethiophosphoramide) is an alkylating agent used to treat cancer

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Sigma Aldrich Fine Chemicals Biosciences Thioguanine United States Pharmacopeia (USP) Reference Standard | 154-42-7 | MFCD00233553 | 200MG

Thioguanine United States Pharmacopeia (USP) Reference Standard | Mol Wt: 167.19 | 154-42-7 | MFCD00233553 | 200MG

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eMolecules​ 119006-77-8 | Medchem Express | Flutrimazole | 10mg | 705860563 | HY-129060 | MFCD00865591 | 346.381 | C22H16F2N2

ChemScene | 5-Hydroxy-1-methyl-1h-pyrazole-4-carboxylic acid | 100mg | 714235362 | CS-0300513 | 1255352-25-0 | MFCD21601625 | 142.114 | C5H6N2O3

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