Drug Standards
![eMolecules Pharmablock / tert-butyl rel-(1R5S6r)-6-formyl-3-azabicyclo[3.1.0]hexane-3-carboxylate / 100mg / 551326178 / PBLG0012 / 0.000 / 419572-19-3 / MFCD18782860 / 211.261 / C11H17NO3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502516734.JPG-250.jpg)
eMolecules Pharmablock / tert-butyl rel-(1R5S6r)-6-formyl-3-azabicyclo[3.1.0]hexane-3-carboxylate / 100mg / 551326178 / PBLG0012 / 0.000 / 419572-19-3 / MFCD18782860 / 211.261 / C11H17NO3
Pharmablock / tert-butyl rel-(1R5S6r)-6-formyl-3-azabicyclo[3.1.0]hexane-3-carboxylate / 100mg / 551326178 / PBLG0012 / 0.000 / 419572-19-3 / MFCD18782860 / 211.261 / C11H17NO3
Apexbio Technology LLC Flumazenil 78755-81-4 25mg
Flumazenil (CAS 78755-81-4) is a centrally active small molecule that functions as a benzodiazepine receptor antagonist It binds to -aminobutyric acid type A (GABA sub A /sub ) receptors without preferential selectivity for subtypes containing 1 2 3 or 5 subunits By competitively inhibiting benzodiazepine binding at these receptors flumazenil modulates GABAergic neurotransmission in the central nervous system This compound is widely utilized in biomedical research to investigate benzodiazepine pharmacology GABA sub A /sub receptor function and the neural mechanisms underlying anxiolytic and sedative drug actions
Selleck Chemical LLC Flavopiridol (Alvocidib) HCl S2679-1g
Flavopiridol (Alvocidib) HCl competes with ATP to inhibit CDKs including CDK1 CDK2 CDK4 and CDK6 with IC50 of 40 nM in cell-free assays It is 7 5-fold more selective for CDK1/2/4/6 than CDK7 Flavopiridol is initially found to inhibit EGFR and PKA Flavopiridol HCl induces autophagy and ER stress Flavopiridol HCl blocks HIV-1 replication Phase 1/2
Sigma Aldrich Fine Chemicals Biosciences Lomustine United States Pharmacopeia (USP) Reference Standard | 13010-47-4 | MFCD00012392 | 200MG
Lomustine United States Pharmacopeia (USP) Reference Standard | Mol Wt: 233.7 | 13010-47-4 | MFCD00012392 | 200MG
Cayman Chemical -FlurbIprofen 10g
A non-selective COX inhibitor (IC50s = 0.04 and 0.51 μM for COX-1 and COX-2, respectively); reduces carrageenan-induced hind paw edema and yeast-induced fever in rats from 0.3-4.8 mg/kg; reduces plasma fibrinogen levels and arthritic score in a rat model of adjuvant-induced arthritis; reduces tumor weight and prostaglandin production and increases survival in a WHT-NC mouse xenograft model at 5 mg/kg
Sigma Aldrich Fine Chemicals Biosciences Methylprednisolone hydrogen succinate European Pharmacopoeia (EP) Reference Standard | 2921-57-5 |
Methylprednisolone hydrogen succinate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 474.54 | 2921-57-5 |
Sigma Aldrich Fine Chemicals Biosciences Sulbactam Related Compound F United States Pharmacopeia (USP) Reference Standard | 24158-88-1 | 15MG
Sulbactam Related Compound F United States Pharmacopeia (USP) Reference Standard | Mol Wt: 359.03 | 24158-88-1 | 15MG
Sigma Aldrich Fine Chemicals Biosciences Frovatriptan Related Compound A United States Pharmacopeia (USP) Reference Standard | 147008-88-6 | 20MG
Frovatriptan Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 229.28 | 147008-88-6 | 20MG
Sigma Aldrich Fine Chemicals Biosciences Diclofenac Compoun100MG
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Medchemexpress LLC O-(2-heptyl) dabigatran ethyl ester | 1610758-21-8 | MFCD03093370 | 10mg
Dabigatran impurity 4 is an impurity of Dabigatran (HY-10163)
Selleck Chemical LLC crizotinib
(S)-crizotinib the (S)-enantiomer of crizotinib is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM in a cell-free assay
Sigma Aldrich Fine Chemicals Biosciences Sulbactam sodium European Pharmacopoeia (EP) Reference Standard | 69388-84-7 |
Sulbactam sodium European Pharmacopoeia (EP) Reference Standard | 69388-84-7 |
Cayman Chemical LenalIdomIde 500mg
A derivative of thalidomide; reduces TNF-α production in isolated human PBMCs and whole blood stimulated by LPS from S. minnesota (IC50s = 13 and 25 nM, respectively); has been used as a building block in the synthesis of PROTACs that induce the degradation of IKZF1 and IKZF3 in MM.1S cells; reduces vascularization and total microvascular length in a rat mesenteric window assay model at 250 mg/kg per day, p.o.
Cayman Chemical Losartan potassium salt
An AT1b antagonist (IC50 = 2.2 nM in COS-7 cells expressing the rat receptor); reduces U-46619-induced aggregation of platelets in isolated human platelet-rich plasma at 5 µM; decreases 1-LO levels in the endothelial layer of autologous vein grafts in rabbits fed a high-cholesterol diet at 10 mg/kg per day; decreases systolic blood pressure in a ouabain-induced mouse model of hypertension at 15 mg/kg per day; increases the mechanical pain threshold in the von Frey test in a paclitaxel-induced rat model of neuropathic pain at 50 mg/kg twice per day
Medchemexpress LLC DOTAP methylsulfate 100mg
DOTAP methylsulfat is a cationic lipid reagent a cationic derivative of trimethylammonium linked to two 18-carbon fatty acid tails each with a single olefin group DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis respectively DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain releases DNA into the cytoplasm and exerts gene delivery function DOTAP methylsulfat can be widely used in research fields such as gene therapy cell transfection and non-viral vector design up [1] up [2]