Drug Standards
Medchemexpress LLC Tofacitinib (citrate) | 540737-29-9 | 99.9% | 504.49 | 25 MG
Tofacitinib citrate is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively. It exhibits antibacterial, antifungal, and antiviral activities.
- Orally available JAK3/2/1 inhibitor.
- IC50s: JAK3 (1 nM), JAK2 (20 nM), JAK1 (112 nM).
- Possesses antibacterial, antifungal, and antiviral activities.
Apexbio Technology LLC Oxibendazole 20559-55-1 200mg
Oxibendazole (CAS 20559-55-1) is a small-molecule inhibitor targeting microtubule polymerization in nematodes It is designed to disrupt cytoskeletal assembly thereby impairing parasite survival Oxibendazole exerts its biological activity primarily through inhibition of microtubule polymerization In in vitro studies oxibendazole demonstrates induction of apoptotic signaling pathways and inhibits proliferation in mammalian tumor cell lines with reported IC50 values for its antiproliferative effect typically ranging from low to mid micromolar levels Based on these pharmacological properties oxibendazole holds research potential in oncology and inflammatory disease models
Medchemexpress LLC Cabozantinib-d6 | 1802168-46-2 | 98.1% | C28H18D6FN3O5 | 10MG
Cabozantinib-d6 is a deuterium-labeled analog of cabozantinib supplied as a 10 mg reference standard for use as a stable isotope internal standard in LC-MS quantitative and pharmacokinetic assays. It supports accurate quantification and method validation in analytical laboratories.
Medchemexpress LLC Amoxicillin impurity 2 | 1356020-01-3 | MFCD18379169 | 100mg
Amoxicillin Impurity 2 is an impurity of Amoxicillin (HY-B0467A)
Apexbio Technology LLC Itraconazole(Synonyms: Sporanox, Orungal, R51211, Lozanoc, Triasporin, Fungitraxx, Onmel, Itranox, Sporal, Itrizole, Candistat), 100mg, CAS: 84625-61-6.
Itraconazole (CAS 84625-61-6) is a triazole-based antifungal compound that functions primarily by inhibiting cytochrome P450 enzymes particularly CYP3A4 As both a substrate and inhibitor of CYP3A4 itraconazole undergoes oxidative metabolism into hydroxylated keto- and N-dealkylated derivatives all with demonstrated inhibitory activities comparable or superior to the parent compound In addition to antifungal effects itraconazole inhibits the hedgehog signaling pathway and angiogenesis Due to its affinity for mammalian CYP-P450 enzymes itraconazole is frequently employed in drug interaction studies assessing CYP3A-mediated metabolism
Medchemexpress LLC Dodecyl gallate | 1166-52-5 | MFCD00002195 | 100.0% | 338.44 g/mol | C19H30O5 | 10MM 1ML
Dodecyl gallate is the dodecyl (lauryl) ester of gallic acid used as an antioxidant and research reagent. It is supplied at high purity and is available as solid material or as a pre-made 10 mM solution in DMSO for biological and analytical applications.
- High purity, reported as 99.99%.
- Available as 10 mM in DMSO solution and multiple solid pack sizes (25 g-500 g and larger).
- Molecular weight 338.44 g/mol; chemical formula C19H30O5.
- Commonly used as an antioxidant and antibacterial reagent in research.
- Pre-dissolved solution reduces preparation time and improves dosing accuracy.
Selleck Chemical LLC Luminespib (NVP-AUY922) 10mM/1mL 747412-49-3 AUY-922
Luminespib (AUY-922, NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90?/? with IC50 of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Luminespib (AUY-922, NVP-AUY922) effectively downregulates and destabilizes the IGF-1R? protein and results in growth inhibition, autophagy and apoptosis. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC Camostat Mesilate 59721-29-8 50mg
Camostat Mesilate (59721-29-8) is a small-molecule inhibitor targeting trypsin-like serine proteases It is designed to suppress protease activity thereby modulating processes such as epithelial sodium channel (ENaC) function and airway surface liquid homeostasis Camostat Mesilate exerts its biological activity primarily through protease inhibition In cell-based studies using airway epithelial cells Camostat Mesilate demonstrates ENaC activity suppression with an IC50 value of 50 nM Based on these pharmacological properties Camostat Mesilate holds research potential in studies of respiratory physiology and pathophysiology particularly those investigating ENaC-mediated ion transport in airway epithelial cell models
Medchemexpress LLC Deschloro dasatinib | 1184919-23-0 | MFCD12408003 | 10mg
Dasatinib impurity 4 (Deschloro Dasatinib) is an impurity of Dasatinib (HY-10181)
Apexbio Technology LLC Sulfamerazine 127-79-7 5g
Sulfamerazine (127-79-7) is a small-molecule inhibitor targeting bacterial dihydropteroate synthase It is designed to competitively inhibit this key enzyme thereby disrupting bacterial folate biosynthesis Sulfamerazine exerts its biological activity primarily through competitive inhibition of bacterial dihydropteroate synthase interfering with dihydrofolic acid production and subsequent DNA and RNA biosynthesis in susceptible bacteria In biochemical assays Sulfamerazine demonstrates inhibitory activity with IC50 values typically reported within the micromolar range depending on the bacterial strain and experimental conditions Based on these pharmacological properties Sulfamerazine holds research potential in elucidating antimicrobial resistance mechanisms studying bacterial metabolic pathways and investigating the molecular biology of bacterial folate synthesis
Apexbio Technology LLC MDV3100 (Enzalutamide), 915087-33-1, MFCD14155804, 10 mg
MF: C21H16F4N4O2S, MW: 464.4, Synonyms: Enzalutamide, MDV3100, MDV-3100, MDV 3100. Solubility: 23.22mg/mL in DMSO. MDV3100, known as Enzalutamide, is a second-generation androgen receptor (AR) signaling inhibitor. It has been demonstrated impressive affinity to the AR compared to the first-generation AR inhibitors. It is able to inhibit binding of androgens to the AR, AR nuclear translocation, and the association of the AR with DNA.
Sigma Aldrich Fine Chemicals Biosciences Alanine European Pharmacop
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. for further information and support please go to the website of the issuing Pharmacopoeia.
Cayman Chemical FlumazenIl-d5 2.5mg
An internal standard for the quantification of flumazenil by GC- or LC-MS
Medchemexpress LLC Dacomitinib impurity 13 | 25mg
Dacomitinib impurity 13 is an impurity of Dacomitinib (HY-13272)