Drug Standards
TARGETMOL CHEMICALS INC Fluvoxamine maleate 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders. Purity 99.97%
Cayman Chemical N-desmethyl ImatInIb 10mg
A major active metabolite of imatinib; formed through demethylation of imatinib by CYP3A4; has the same in vitro potency at Bcr-ABL kinase as imatinib (IC50 = 38 nM for both) but is only present in plasma at 10-15% of the levels of imatinib
Apexbio Technology LLC H1 histamine receptor antagonist. Clemizole hydrochloride 5mg. 728865-23-4. MFCD22665727
H1 histamine receptor antagonist. Clemizole hydrochloride 5mg. 728865-23-4. MFCD22665727
Medchemexpress LLC Ethyl 2-oxo-2-(pyridin-2-ylamino)acetate | 41374-72-5 | MFCD02317206 | 25mg
Edoxaban Impurity 8 is an impurity of Edoxaban (HY-10264)
Selleck Chemical LLC Tacedinaline10mg
Tacedinaline (CI994, PD-123654, GOE-5549, Acetyldinaline) is a selective class I HDAC inhibitor with IC50 of 0.9, 0.9, 1.2, and >20 ?M for human HDAC 1, 2, 3, and 8, respectively. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Med Vet International Diclofenac Sodium Topical Gel (voltaren) 1% 100gm
Diclofenac Sodium Topical Gel (voltaren) 1% 100gm
Medchemexpress LLC Lenalidomide-C4-NH2 50mg | 2435715-90-3 | 351.83 g/mol | C17H22ClN3O3 | 50 MG
Lenalidomide-C4-NH2 hydrochloride is a lenalidomide-derived cereblon (CRBN) ligand supplied as the hydrochloride salt for research use. It is used as a CRBN-recruiting moiety in targeted protein degradation (PROTAC) design and in biochemical and cell-based assays.
- Serves as a cereblon (CRBN) binding ligand for recruitment of E3 ubiquitin ligase.
- Provided as the hydrochloride salt for improved handling and solubility.
- Typical purity ~95.8%, suitable for research applications.
- Molecular weight 351.83 g/mol and formula C17H22ClN3O3.
- Soluble in DMSO and compatible with linker conjugation chemistries for PROTAC synthesis.
- Available in multiple pack sizes for research-scale use.
AdipoGen Dibucaine hydrochloride
Chemical. CAS 61-12-1. Formula C20H29N3O2 . HCl. MW 343.4 . 36.5. Synthetic. Dibucaine is a long-acting local anesthetic. Potent Na channel blocker. It blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membranes permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade. Induces apoptosis through calpain, cytochrome oxidase etc, and shows antiviral and antiparasitic activity.
Medchemexpress LLC Ketoprofen impurity 5g
Ketoprofen impurity 1 is an impurity of Ketoprofen (HY-B0227)
Apexbio Technology LLC Cabazitaxel 183133-96-2 10mg
Cabazitaxel (CAS 183133-96-2) is a semisynthetic compound derived from the natural precursor 10-deacetylbaccatin III belonging to the taxoid class of antineoplastic agents It exerts its biological effects primarily by stabilizing microtubules thus disrupting mitotic and interphase cellular functions and causing cell-cycle arrest leading to apoptosis Due to this microtubule-targeting activity cabazitaxel is extensively studied in oncology research particularly investigating chemoresistant tumor cell lines and therapeutic approaches for taxane-resistant cancers
Cayman Chemical R-CrIzotInIb 100mg
A dual inhibitor of c-Met and ALK (IC50s = 8 and 20 nM, respectively, in a cell-based assay); selective for c-Met and ALK over several other receptor and non-receptor tyrosine kinases, including Ron, Tie2, Abl, LCK, and VEGFR2 (IC50s = 0.08, 0.448, 1.159, 2.741, and >10 µM, respectively); selectively inhibits the proliferation of cancer cell lines with MET amplifications over cancer cell lines with MET or EGFR mutations (IC50s = 5-10, 472-1,284, and 767-787 nM, respectively); induces apoptosis in MET-amplified EBC-1 and NCI H1993 cells at 100 nM; reduces tumor volume in an EBC-1 mouse xenograft model at 25 mg/kg
Medchemexpress LLC Rosuvastatin lactone | 503610-43-3 | MFCD16621107 | 98.6% | C22H26FN3O5S | 10MG
Rosuvastatin lactone is the lactone metabolite of rosuvastatin supplied as an analytical standard for research use only. It is intended for metabolite identification, quantification, and analytical method development in biochemical and pharmaceutical research. The material is provided as a solid with a reported purity of approximately 98.6% and the molecular formula C22H26FN3O5S (MW 463.52 g/mol).
- Intended for research and analytical use only.
- High purity (98.6%) suitable for analytical assays.
- Molecular formula C22H26FN3O5S and molecular weight 463.52 g/mol.
- Available in milligram-scale packages for standards and method development.
- Supplied with datasheet and certificate of analysis for batch verification.
Accela Chembio Inc Isomannide | 100g | 641-74-7 | MFCD10698761 | 96% | Shelf Life: 2520 Days | Regular
Isomannide | 100g | 641-74-7 | MFCD10698761 | 96% | Shelf Life: 2520 Days | Regular
Apexbio Technology LLC Divalproex Sodium 76584-70-8 50mg
Divalproex Sodium (CAS 76584-70-8) is a small-molecule inhibitor targeting histone deacetylases (HDACs) and modulating GABAergic neurotransmission It is designed to inhibit HDACs and modulate associated signaling pathways thereby regulating neuronal excitability and gene expression Divalproex Sodium exerts its biological activity primarily through HDAC inhibition enhancement of GABA levels inhibition of voltage-gated sodium channels and modulation of NMDA receptor-mediated glutamatergic signaling In experimental studies Divalproex Sodium demonstrates HDAC inhibitory activity with reported IC50 values typically ranging between 400 600 M varying by assay Based on these pharmacological properties Divalproex Sodium holds research potential in epilepsy bipolar disorder and migraine prophylaxis
Selleck Chemical LLC Dicloxacillin Sodium hydrate
Dicloxacillin Sodium hydrate (DLX Dycill Dynapen Pathocil) a narrow-spectrum -Lactam antibiotic of the penicillin class induces drug-metabolizing CYP enzymes to a clinically relevant extent