Ion Chromatography Standards
Apexbio Technology LLC IBC 293 306935-41-1 1g
IBC 293 (CAS 306935-41-1) is a selective agonist of the G protein-coupled receptor GPR109b By activating GPR109b IBC 293 modulates specific signaling pathways involved in the regulation of lipid and glucose metabolism The compound exhibits high affinity for the human GPR109b receptor with a reported pEC50 of approximately 6 4 IBC 293 serves as a valuable research tool for elucidating GPR109b-mediated mechanisms and receptor function in the context of metabolic syndrome and cardiovascular disease models
Apexbio Technology LLC DL-Adrenaline 329-65-7 1g
DL-Adrenaline is a non-selective agonist targeting alpha- and beta-adrenergic receptors It is designed to activate these adrenergic receptors thereby modulating downstream cellular signaling pathways involved in vascular contraction cardiac stimulation and bronchodilation DL-Adrenaline exerts its biological activity primarily through adrenergic receptor activation Based on these pharmacological properties DL-Adrenaline holds research potential in the study of adrenergic receptor function and downstream signaling in cardiovascular respiratory and neurophysiological processes as well as serving as a reference molecule for experimental assays investigating receptor affinity selectivity and activation pathways
Waters Corporation Ion Calibration Standard, Chlorite, 1000 mg/L, 125 mL
This Chlorite Ion Calibration Standard, with a concentration of 1000 mg/L in an H2O matrix, is designed for primary calibration or for preparing second source calibration check standards. It is traceable to NIST Standard Reference Materials, where available, and is guaranteed stable for one year.
- Formulation: Liquid
- Application: Environment
- Traceability to NIST Standard Reference Materials, where available
- Guaranteed stable for one year
Apexbio Technology LLC WZ811 55778-02-4 1g
WZ811 (CAS 55778-02-4) is a small molecule antagonist targeting the CXC chemokine receptor 4 (CXCR4) Structurally composed of two aromatic amine groups WZ811 inhibits the binding of TN14003 to CXCR4 with an EC50 of 0 3 nM and disrupts stromal cell-derived factor 1 (SDF-1)-mediated CXCR4 signaling In cAMP assays WZ811 significantly attenuates SDF-1-induced cAMP responses and impedes SDF-1-driven Matrigel invasion (EC50 5 2 nM) Given CXCR4 s involvement in infection inflammation and various diseases WZ811 serves as a valuable tool for interrogating CXCR4-related biological processes and disease models and has been reported to display modest anti-HIV activity in cell cultures
Apexbio Technology LLC Tebuconazole 107534-96-3 1g
Tebuconazole (CAS 107534-96-3) is a small-molecule inhibitor targeting CYP51 a key enzyme in fungal sterol biosynthesis It modulates CYP51 activity to regulate sterol production within fungal cells Tebuconazole exerts its biological activity primarily through inhibition of CYP51 In cell-based assays tebuconazole demonstrates inhibitory activity with an IC50 value of 0 9 M against CaCYP51 from Candida albicans and 1 3 M against truncated human 60HsCYP51 Additionally in HepG2 cells tebuconazole induces lipid accumulation and oxidative stress and in mammary epithelial MAC-T cells it reduces proliferation and induces endoplasmic reticulum stress-mediated apoptosis Based on these pharmacological properties tebuconazole holds research potential in studies of fungal sterol biosynthesis cellular stress response pathways and apoptosis mechanisms
Apexbio Technology LLC Casanthranol 8024-48-4 1g
Casanthranol is a natural mixture of anthranol glycosides derived from the bark of Rhamnus purshiana commonly known as cascara sagrada Casanthranol exerts its biological activity primarily through intestinal bacterial hydrolysis releasing anthraquinone aglycones that interact with colonic mucosa to enhance bowel motility and stimulate fluid accumulation in the intestinal lumen Based on these pharmacological properties casanthranol holds research potential in studies of intestinal motility investigation of laxative mechanisms microbiota-mediated glycoside metabolism and as a chemical probe for elucidating gastrointestinal physiology and anthraquinone glycoside bioactivity
Apexbio Technology LLC PNPG 2492-87-7 1g
PNPG (2492-87-7) is a chromogenic substrate utilized for quantitative determination of -D-glucosidase activity It is designed to enable measurement of -D-glucosidase-mediated hydrolysis thereby facilitating assessment of glucosidase function and glucoside breakdown pathways PNPG exerts its biological activity primarily through enzymatic hydrolysis by -D-glucosidase producing para-nitrophenol which exhibits a yellow color detectable at 405 nm via spectrophotometry Based on these properties PNPG holds research potential in biochemical assays for measuring -D-glucosidase activity enzyme kinetics and studies of glucose metabolism in biomedical and pharmacological research
THERMO SCI 3P AIG PARTS & ACCESSORIES CHROMELEN CAFF 10ML 6X10ML
NC0396871 CHROMELEN CAFF 10ML 6X10ML
