Ion Chromatography Standards
Apexbio Technology LLC L-Phenylephrine 59-42-7 1g
L-Phenylephrine (CAS 59-42-7) is a selective agonist of the adrenergic 1A receptor exhibiting a Ki of 1 4 M with markedly lower affinity for 1B (Ki 23 9 M) and 1C (Ki 47 8 M) subtypes In vitro L-Phenylephrine has been shown to reduce apoptosis in neonatal rat cardiomyocytes following hypoxia and serum deprivation and to stimulate proliferation in neural progenitor cells It also increases the cross-sectional area and modulates gene expression in rat neonatal cardiomyocytes In vivo local administration in rats induces cutaneous anesthesia through 1-adrenergic receptor activation and clinical data suggest oral administration reduces nasal airway resistance These properties make L-Phenylephrine a valuable tool for studying 1A-adrenergic receptor-mediated cellular responses
Apexbio Technology LLC Cephalexin monohydrate 23325-78-2 1g
Cephalexin monohydrate (CAS 23325-78-2) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby impairing bacterial cell wall synthesis and compromising cell wall integrity Cephalexin monohydrate exerts its biological activity primarily through disruption of bacterial cell wall cross-linking leading to cell lysis In in vitro studies cephalexin monohydrate demonstrates inhibitory activity with reported MIC values ranging from 0 5 g/mL to 32 g/mL depending on bacterial species and experimental conditions IC50 values are dependent upon specific bacterial strains evaluated Based on these pharmacological properties cephalexin monohydrate holds research potential in antimicrobial susceptibility testing bacterial resistance studies and related microbiological assays
Apexbio Technology LLC EDTA 60-00-4 1g
EDTA (60-00-4) is a chelating agent targeting polyvalent metal ions such as calcium magnesium and iron It is designed to sequester metal ion cofactors thereby inhibiting metal-dependent enzymatic reactions and stabilizing proteins EDTA exerts its biological activity primarily through the formation of stable coordination complexes with metal ions preventing their participation in biochemical processes In biochemical and cell culture studies EDTA demonstrates inhibition of metal-dependent enzymes and preservation of reagent stability Based on these pharmacological properties EDTA holds research potential in protein purification nucleic acid isolation enzyme assays chromatography coronary artery disease and neurological disease studies
Inorganic Ventures 1000µg/mL STRONTIUM 125mL
Matrix: Nitric Acid (HNO3), Starting Material: SrCO3, Analyte: Sr+2 1000 ug/mL.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
![Medchemexpress LLC 2-[(6-amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone | 371242-69-2 | MFCD09970845 | >98.0% | 397.4 g/mol | C22H19N7O | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000211422.png-250.jpg)
Medchemexpress LLC 2-[(6-amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone | 371242-69-2 | MFCD09970845 | >98.0% | 397.4 g/mol | C22H19N7O | 1 ML
IC-87114 is a selective small-molecule inhibitor of PI3Kδ (p110δ) used in research to probe PI3K signaling and immune-cell functions. It displays reported potency (IC50 ≈ 0.5 μM) and is supplied as a 10 mM solution in a 1 mL vial for analytical and experimental use.
- Selective inhibition of PI3Kδ (p110δ).
- Potent activity with IC50 ~0.5 μM.
- Supplied as a 10 mM solution in a 1 mL vial.
- High purity suitable for research use.
- Applicable to immunology and cell-signaling studies.
Apexbio Technology LLC Nikethamide 59-26-7 1g
Nikethamide is a small-molecule respiratory stimulant designed to modulate the respiratory center in the medulla oblongata thereby regulating central respiratory sensitivity Nikethamide exerts its biological activity primarily through modulation of neural pathways within the central nervous system potentially involving nicotinic receptors and neurotransmitter signaling cascades Based on these pharmacological properties Nikethamide holds research potential in investigating respiratory dysfunction respiratory failure and the signaling mechanisms governing respiratory neural control
Apexbio Technology LLC Pasiniazid 2066-89-9 1g
Pasiniazid (CAS 2066-89-9) is a small-molecule inhibitor targeting enzymes essential for mycolic acid biosynthesis in mycobacteria It is designed to disrupt cell wall synthesis thereby inhibiting the growth of Mycobacterium tuberculosis and Mycobacterium leprae Pasiniazid exerts its biological activity primarily through inhibition of mycolic acid biosynthesis In in vitro antimicrobial assays and animal infection models Pasiniazid demonstrates inhibitory activity with reported IC50 values against mycobacterial targets typically within micromolar concentrations Based on these pharmacological properties Pasiniazid holds research potential in the investigation of tuberculosis and leprosy pathogenesis including studies on drug-response relationships resistance mechanisms and pharmacokinetics
Apexbio Technology LLC L-α-Aminoadipic Acid 1118-90-7 1g
L-alpha-Aminoadipic Acid (1118-90-7) is a small-molecule inhibitor targeting glutamine synthetase It is designed to competitively inhibit glutamine synthetase activity thereby modulating glutamate metabolism and neurotransmission pathways L-alpha-Aminoadipic Acid exerts its biological activity primarily through stereospecific competitive inhibition of glutamine synthetase In in vitro studies L-alpha-Aminoadipic Acid impacts astrocytic function preceding its gliotoxic effects and modulates kynurenic acid production in hippocampal tissues Based on these pharmacological properties L-alpha-Aminoadipic Acid holds research potential in the investigation of astrocyte function and neurological metabolism within neuroscience and pharmacology fields
Apexbio Technology LLC Acetarsone 97-44-9 1g
Acetarsone (97-44-9) is a small-molecule anti-infective and antiparasitic agent belonging to the organoarsenic group of compounds It is proposed to modulate parasite-specific metabolic enzymes or interfere with biochemical pathways essential for parasite survival Acetarsone exerts its biological activity primarily through inhibition of parasite biochemical pathways however the exact molecular targets and mechanism remain to be fully elucidated In both in vitro and in vivo studies acetarsone demonstrates antiparasitic activity with IC50 values reported in the low to moderate micromolar range depending on parasite species and experimental conditions Based on these pharmacological properties acetarsone holds research potential in the treatment of protozoan infections and in studies of intestinal inflammation and mucosal pathology
Apexbio Technology LLC Minoxidil 38304-91-5 1g
Minoxidil (CAS 38304-91-5) is a synthetic pyrimidine derivative that functions as a direct-acting vasodilator It exerts its pharmacological effects by opening ATP-sensitive potassium channels in vascular smooth muscle cells leading to membrane hyperpolarization and subsequent relaxation of arterial smooth muscle These actions result in reduced peripheral vascular resistance and lower blood pressure Minoxidil is widely utilized in biomedical research to investigate mechanisms of vasodilation vascular smooth muscle physiology and the role of potassium channels in cardiovascular regulation
Apexbio Technology LLC Chondroitin sulfate 9007-28-7 1g
Chondroitin sulfate (9007-28-7) is a glycosaminoglycan designed to modulate inflammatory and apoptotic processes thereby regulating extracellular matrix homeostasis Chondroitin sulfate exerts its biological activity primarily by inhibiting inflammatory mediators and reducing cell apoptosis through interactions with various biological molecules Based on these pharmacological properties chondroitin sulfate holds research potential in investigating cartilage degradation inflammatory response mechanisms and therapeutic targets related to joint degeneration and tissue remodeling
Apexbio Technology LLC Aripiprazole 129722-12-9 1g
Aripiprazole (CAS 129722-12-9) is a non-typical antipsychotic compound characterized as a dopamine-serotonin system stabilizer It acts as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and exhibits antagonist properties at 5-HT2A receptors Binding studies indicate high affinity to D2 receptors with reported Kd values of 0 34 0 02 nM (agonist radioligand [125I]7-OH-PIPAT) and 0 70 0 22 nM (antagonist [3H]spiperone) In cellular assays aripiprazole inhibits forskolin-induced cAMP accumulation in CHO and HEK-293 cells and suppresses quinpirole-stimulated GTPase activity in rat striatal membranes These properties position aripiprazole as a valuable tool for investigating dopaminergic and serotonergic signaling pathways
Apexbio Technology LLC Spermine 71-44-3 1g
Spermine (71-44-3) is a small-molecule inhibitor targeting inward rectifier potassium (K ) channels It is designed to block channel conductance thereby modulating cellular excitability and resting membrane potential Spermine exerts its biological activity primarily through direct inhibition of K channel function In experimental studies spermine demonstrates strong channel inhibition with an IC50 value of approximately 31 nM at a membrane potential of 50 mV in cloned IRK1 potassium channels Based on these pharmacological properties spermine holds research potential in potassium channel modulation neuronal excitability studies and investigation of neurological conditions associated with altered glutamatergic signaling and polyamine metabolism
Apexbio Technology LLC Nizatidine 76963-41-2 1g
Nizatidine (CAS 76963-41-2) is a small molecule inhibitor primarily characterized as a potent histamine H2 receptor antagonist exhibiting an IC50 of 0 9 nM for this target In addition to its H2 receptor antagonism nizatidine also demonstrates inhibition of acetylcholinesterase (AChE) activity with an IC50 of 6 7 M These dual inhibitory properties make nizatidine a useful tool for investigating pathways involving gastric acid secretion and cholinergic neurotransmission in biomedical research settings