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Filtered Search Results
eMolecules 41717-28-6 | Ambeed | Benzofuran-2-carbonyl chloride | 100mg | 572825044 | A624914 | MFCD01659782 | 180.59 | C9H5ClO2
Ambeed | 2-Chloro-3-iodo-4-methylpyridine | 1g | 642080732 | A442340 | 926922-28-3 | MFCD11878566 | 253.470 | C6H5ClIN
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eMolecules AstaTech / 7-METHYL-7H-PYRROLO[23-D]PYRIMIDINE-5-CARBOXYLIC ACID / 0.25g / 290678997 / P13113 / 95.000 / 1499578-19-6 / MFCD22370977 / 177.163 / C8H7N3O2
AstaTech / 7-METHYL-7H-PYRROLO[23-D]PYRIMIDINE-5-CARBOXYLIC ACID / 0.25g / 290678997 / P13113 / 95.000 / 1499578-19-6 / MFCD22370977 / 177.163 / C8H7N3O2
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eMolecules 1694-57-1 | Ambeed | (2-Chlorophenyl)(pyridin-2-yl)methanone | 100mg | 600841404 | A482284 | MFCD07699234 | 217.65 | C12H8ClNO
Ambeed | 6-Aminohexanenitrile | 250mg | 599356740 | A630649 | 2432-74-8 | MFCD00009822 | 112.176 | C6H12N2
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eMolecules 53902-75-3 | PYRAZOLO[1,5-B]PYRIDAZINE-2-CARBOXYLIC ACID | AstaTech | MFCD18381193 | 163.136 | C7H5N3O2 | 95.000 | OC(=O)c1cc2cccnn2n1 | 0.1g | 290677104
PYRAZOLO[1,5-B]PYRIDAZINE-2-CARBOXYLIC ACID | AstaTech | 53902-75-3 | MFCD18381193 | 163.136 | C7H5N3O2 | 95.000 | OC(=O)c1cc2cccnn2n1 | 0.1g | 290677104
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Medchemexpress LLC N-hydroxy-4-((quinolin-8-ylamino)methyl)benzamide | 2151853-97-1 | 99.8% | 293.32 g/mol | C17H15N3O2 | 25MG
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MPT0G211 is a potent, orally active, and selective histone deacetylase 6 (HDAC6) inhibitor used for preclinical research. It exhibits sub-nanomolar potency against HDAC6 (IC50 = 0.291 nM), strong selectivity over other HDAC isoforms, and is reported to penetrate the blood-brain barrier. Reported activities include reduction of tau phosphorylation and improvement of cognitive deficits in Alzheimer's disease models, along with anti-metastatic, neuroprotective, and anticancer effects.
- Potent HDAC6 inhibition (IC50 = 0.291 nM)
- >1,000-fold selectivity for HDAC6 versus other HDAC isoforms
- Orally active with reported blood-brain barrier penetration
- Demonstrated reduction of tau phosphorylation in disease models
- Reported cognitive benefit in Alzheimer's disease model studies
- High reported purity suitable for research use (≈99.8%)
- Available in small research pack sizes for in vitro and in vivo studies
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eMolecules 619-67-0 | 4-Hydrazinobenzoic acid | Ambeed | MFCD00007581 | 152.153 | C7H8N2O2 | 98.000 | NNc1ccc(cc1)C(O)=O | 5g | 525877085
4-Hydrazinobenzoic acid | Ambeed | 619-67-0 | MFCD00007581 | 152.153 | C7H8N2O2 | 98.000 | NNc1ccc(cc1)C(O)=O | 5g | 525877085
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eMolecules 487-89-8 | Indole-3-carboxaldehyde | Ambeed | MFCD00005622 | 145.161 | C9H7NO | 98.000 | O=Cc1c[nH]c2ccccc12 | 10g | 552604198
Indole-3-carboxaldehyde | Ambeed | 487-89-8 | MFCD00005622 | 145.161 | C9H7NO | 98.000 | O=Cc1c[nH]c2ccccc12 | 10g | 552604198
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Medchemexpress LLC Ygsy2p-IN-1 | 2415003-97-1 | 98.6% | 50 MG
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yGsy2p-IN-1 is a potent inhibitor for yeast glycogen synthase 2 (yGsy2p) and a competitive human glycogen synthase 1 (hGYS1) inhibitor. It is a pyrazole inhibitor used for glycogen storage diseases (GSDs).
- Potent inhibitor for yeast glycogen synthase 2 (yGsy2p)
- Competitive human glycogen synthase 1 (hGYS1) inhibitor with an IC50 of 2.75 μM and a Ki of 1.31 μM for wild-type hGYS1
- Used for glycogen storage diseases (GSDs)
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Medchemexpress LLC Cyprodinil | 121552-61-2 | 98.8% | 225.29 | 50 MG
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Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide known for its anti-androgenic and androgenic activities. It functions by inhibiting methionine biosynthesis in plant-pathogenic fungi, offering protection to fruits and vegetables from various pathogens. This compound also acts as an activator of the aryl hydrocarbon receptor.
- Inhibits methionine biosynthesis in plant-pathogenic fungi
- Protects fruits and vegetables from various pathogens
- Exhibits anti-androgenic and androgenic activities
- Activator of the aryl hydrocarbon receptor
- Increases protein expression of CYP1A1
- Induces phosphorylation of ERK1/2
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eMolecules 859536-27-9 | [1,2,4]Thiadiazole-5-carboxylic acid | J&W PharmLab LLC | MFCD22071363 | 130.120 | C3H2N2O2S | 95.000 | OC(=O)c1ncns1 | 500mg | 718379690
[1,2,4]Thiadiazole-5-carboxylic acid | J&W PharmLab LLC | 859536-27-9 | MFCD22071363 | 130.120 | C3H2N2O2S | 95.000 | OC(=O)c1ncns1 | 500mg | 718379690
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Medchemexpress LLC 2,4-Pyrimidinediamine, N2-1H-benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)- | 1216665-49-4 | 99.9% | 332.36 | 50 MG
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APY29 is an ATP-competitive inhibitor and an allosteric modulator of IRE1α. It inhibits IRE1α autophosphorylation by binding to its ATP-binding pocket with an IC50 of 280 nM. Additionally, APY29 functions as a ligand that allosterically activates the adjacent RNase domain of IRE1α.
- ATP-competitive inhibitor of IRE1α
- Allosteric modulator of IRE1α
- Inhibits IRE1α autophosphorylation with an IC50 of 280 nM
- Acts as a ligand that allosterically activates the IRE1α adjacent RNase domain
- Divergently modulates the RNase activity and oligomerization state of IRE1α
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Medchemexpress LLC Acetylarenobufagin | 184673-79-8 | 1 MG
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Acetylarenobufagin is a steroidal hypoxia inducible factor-1 (HIF-I) modulator. It is intended for research use only.
- Purity of 98.63%
- Molecular weight of 458.54
- Chemical formula is C26H34O7
- Appears as a solid
- Color is white to off-white
- Classified as a steroid
- Initially sourced from animals (toad)
- Targets HIF-I
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Medchemexpress LLC Beta-Zearalanol | 42422-68-4 | 5 MG
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Beta-Zearalenol is a mycotoxin produced by Fusarium spp, which induces apoptosis and oxidative stress in mammalian reproductive cells. It is a derivative of zearalenone (ZEA) and can conjugate with glucuronic acid.
- Purity 99.83%
- Appearance solid, white to off-white
- Molecular weight 322.40
- Formula C18H26O5
- Source microorganisms
- Inhibits BGC proliferation in a dose-dependent manner
- Shows high toxicity in HepG2 cells
- Exhibits synergistic effects with ZEA or α-ZOL in HepG2 cells
- Highest inhibitory effect on IL-8, IL-1β, and TNF-α
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eMolecules 911314-43-7 | tert-Butyl 2-chloro-4-fluorobenzoate | Ambeed | MFCD09800898 | 230.660 | C11H12ClFO2 | 98.000 | CC(C)(C)OC(=O)c1ccc(F)cc1Cl | 250mg | 602849948
tert-Butyl 2-chloro-4-fluorobenzoate | Ambeed | 911314-43-7 | MFCD09800898 | 230.660 | C11H12ClFO2 | 98.000 | CC(C)(C)OC(=O)c1ccc(F)cc1Cl | 250mg | 602849948
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eMolecules 103854-64-4 | Ambeed | 8-Methoxyquinoline-2-carbaldehyde | 250mg | 601095581 | A166382 | MFCD05864557 | 187.198 | C11H9NO2
Ambeed | 444-(Pyridine-246-triyl)tribenzoic acid | 100mg | 682928650 | A1271742 | 107063-53-6 | 439.423 | C26H17NO6
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