Acetylides
Medchemexpress LLC Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 1,1-dimethylethyl ester | 1807503-80-5 | 95.0% | 1 G
Propargyl-PEG2-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Functions as a PEG-based PROTAC linker
- Used for synthesizing PROTACs
- Acts as a click chemistry reagent
- Contains an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules
eMolecules 106-96-7 | 3-Bromo-1-Propyne(80% wt.in toluene) | AA Blocks LLC | MFCD00000241 | 118.961 | C3H3Br | 0.000 | BrCC#C | 25g | 586018240
3-Bromo-1-Propyne(80% wt.in toluene) | AA Blocks LLC | 106-96-7 | MFCD00000241 | 118.961 | C3H3Br | 0.000 | BrCC#C | 25g | 586018240
Medchemexpress LLC Propargyl-PEG24-amine | 00-00-0 | 98.0% | 1112.34 | C51H101NO24 | 5 MG
Propargyl-PEG24-amine is a PEG24-based linker bearing a terminal propargyl (alkyne) group for copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is intended for PROTAC synthesis, bioconjugation, and other applications requiring a hydrophilic PEG spacer with a reactive alkyne handle. Supplied as a white to off-white solid of high purity; store under nitrogen at -20 °C for long-term storage (in solution: -80 °C up to 6 months, -20 °C up to 1 month).
- PEG24 spacer provides flexible hydrophilic linker
- Terminal propargyl group enables CuAAC click chemistry
- High purity (98.0%) for synthesis and conjugation
- Molecular weight ~1112.34 Da suitable for spacing applications
- Solid form simplifies storage and handling
- Recommended storage under nitrogen to maintain stability
(C)C#C | 10g | 533767441](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000188291.jpg-250.jpg)
eMolecules 1066-54-2 | Ethynyltrimethylsilane | AA Blocks LLC | MFCD00008569 | 98.220 | C5H10Si | 0.000 | C[Si](C)(C)C#C | 10g | 533767441
Ethynyltrimethylsilane | AA Blocks LLC | 1066-54-2 | MFCD00008569 | 98.220 | C5H10Si | 0.000 | C[Si](C)(C)C#C | 10g | 533767441
Matrix Scientific 4-ETHYNYLBENZOIC ACID METHY-1G
4-Ethynylbenzoic acid methyl ester, 97%; 1g,C10H8O2, MFCD00168820, mw 160.17, [3034-86-4]
Medchemexpress LLC Propargyl-PEG9-amine | 2093153-98-9 | 97.0% | 100 MG
Propargyl-PEG9-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that possess Azide groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an alkyne group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with molecules possessing azide groups
Medchemexpress LLC Propargyl-PEG9-amine | 2093153-98-9 | 97.0% | 1 G
Propargyl-PEG9-amine is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs and functions as a click chemistry reagent, containing an Alkyne group. It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that contain Azide groups. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Functions as a click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
- Supports selective degradation of target proteins
Medchemexpress LLC Propargyl-PEG3-amine | 932741-19-0 | ≥98.0% | 187.24 | 250 MG
Propargyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
- PEG-based PROTAC linker
- Functions as a click chemistry reagent
- Contains an alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with molecules containing azide groups
- Used in the synthesis of PROTACs
Medchemexpress LLC VH032-PEG3-acetylene | 2098799-80-3 | 98.1% | 25 MG
VH032-PEG3-acetylene is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. This compound is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates a VH032 based VHL ligand
- Utilizes a linker employed in PROTAC technology
- Functions as a click chemistry reagent
- Contains an alkyne group
- Capable of copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups