Acetylides
Selleck Chemical LLC AZ 628 S2746-25mg
AZ628 is a new pan-Raf inhibitor for BRAF BRAFV600E and c-Raf-1 with IC50 of 105 nM 34 nM and 29 nM in cell-free assays also inhibits VEGFR2 DDR2 Lyn Flt1 FMS etc AZ628 induces apoptosis
Medchemexpress LLC Fmoc-amino-PEG3-CH2COOH | 139338-72-0 | 99.8% | 429.46 | 1 G
Fmoc-amino-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is for research use only.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
eMolecules 3-Chloro-4-(trifluoromethoxy)phenol | 1000339-94-5 | MFCD04972754 | 1g
Combi-Blocks | 3-Chloro-4-(trifluoromethoxy)phenol | 1g | 205391475 | OR-6397 | 97.000 | 1000339-94-5 | MFCD04972754 | 212.550 | C7H4ClF3O2
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Medchemexpress LLC Propargyl-PEG12-OH 50mg | 1036204-61-1 | 584.69 | C27H52O13 | 50 MG
Propargyl-PEG12-OH is a PEG12-based linker bearing a terminal propargyl (alkyne) group and a hydroxyl terminus, intended for use as a click-chemistry-compatible spacer in PROTAC synthesis and bioconjugation. It has a molecular weight of 584.69 and CAS 1036204-61-1, and is supplied as a small laboratory vial.
- Terminal alkyne for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- PEG12 spacer increases flexibility and aqueous solubility.
- Hydroxyl terminus enables further functionalization or conjugation.
- Analytical purity ≥98.0% (NMR) suitable for synthetic applications.
- Recommended storage: pure form -20°C (3 years) or 4°C (2 years).
CHARLES LONG DBA RR SCIENTIFIC LLC 7-HEXADECYNE 1G CAS 74685-28-2
NC3072166 7-HEXADECYNE 1G CAS 74685-28-2
Medchemexpress LLC Fmoc-amino-PEG3-CH2COOH | 139338-72-0 | 99.8% | 429.46 | 500 MG
Fmoc-amino-PEG3-CH2COOH is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs, which are molecules containing two different ligands connected by a linker. One ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
Medchemexpress LLC Propargyl-PEG7-Boc | 1818294-29-9 | 100 MG
Propargyl-PEG7-Boc is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. PROTACs are compounds composed of two distinct ligands joined by a linker; one ligand binds to an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is for research purposes only and not for human use.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Alkyne group for CuAAc reactions
- Enables selective degradation of target proteins
Medchemexpress LLC Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]- | 7218-43-1 | 99.7% | 1 G
Propargyl-PEG2-OH is a PEG-based PROTAC linker. It functions as a click chemistry reagent, possessing an alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. This compound can be utilized in the synthesis of Thalidomide-O-PEG2-propargyl.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Utilized in the synthesis of thalidomide-O-PEG2-propargyl
Medchemexpress LLC 3,6,9,12,15,18,21-Heptaoxatetracos-23-yn-1-ol | 1422023-54-8 | ≥97.0% | 250 MG
Propargyl-PEG7-alcohol is a chemical compound identified by CAS number 1422023-54-8. It has a molecular formula of C17H32O8 and a molecular weight of 364.43. This compound is typically found as a colorless to light yellow liquid, with a purity of ≥97.0%. It is intended for research use only.
- Molecular formula: C17H32O8
- Molecular weight: 364.43
- Purity: ≥97.0%
- Appearance: colorless to light yellow liquid
- Storage for pure form: 3 years at -20°C, 2 years at 4°C
- Storage in solvent: 6 months at -80°C, 1 month at -20°C