Acetylides
Medchemexpress LLC Propargyl-PEG6-NH2 | 1198080-04-4 | 99.7% | 5 G
Propargyl-PEG6-NH2 is a PEG-based PROTAC linker that functions as a click chemistry reagent. It contains an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. This reagent is primarily used in the synthesis of PROTACs, which leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Alkyne group
- Engages in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with molecules possessing Azide groups
Medchemexpress LLC Propargyl-PEG9-amine | 2093153-98-9 | 97.0% | 25 MG
Propargyl-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Alkyne group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups
STA Pharmaceutical 2'-propargyl G(iBu) amidite | 10 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 10 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
eMolecules 1256345-96-6 | 3-Butoxy-5-(trifluoromethoxy)phenylboronic acid | Combi-Blocks | MFCD16036112 | 278.030 | C11H14BF3O4 | 97.000 | CCCCOc1cc(OC(F)(F)F)cc(c1)B(O)O | 1g | 117524581
3-Butoxy-5-(trifluoromethoxy)phenylboronic acid | Combi-Blocks | 1256345-96-6 | MFCD16036112 | 278.030 | C11H14BF3O4 | 97.000 | CCCCOc1cc(OC(F)(F)F)cc(c1)B(O)O | 1g | 117524581
Medchemexpress LLC Propargyl-PEG1-bromide | 18668-74-1 | MFCD00099299 | 98.0% | 163.01 g/mol | C5H7BrO | 250 MG
Propargyl-PEG1-bromide is a PEG-derived reagent bearing a propargyl (alkynyl) group and a terminal bromide. It serves as a reactive building block for introducing a short PEG1 spacer with an alkyne handle in synthesis workflows for chemical biology, bioconjugation, and drug delivery linker development.
- Small PEG spacer with propargyl functional group.
- Terminal bromide for alkylation or nucleophilic substitution reactions.
- Compatible with click chemistry and linker installation workflows.
- Useful for drug delivery and bioconjugation research applications.
- Molecular weight 163.01 g/mol.
- Chemical formula C5H7BrO.
- CAS number 18668-74-1.
- Typical purity 98.0%.
Medchemexpress LLC Propargyl-PEG4-Boc | 1355197-66-8 | 316.39 | 1 G
Propargyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Alkyne group
- Can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
eMolecules 1066-54-2 | Trimethylsilylacetylene | Chem-Impex | MFCD00008569 | 98.220 | C5H10Si | 99.000 | C[Si](C)(C)C#C | 1kg | 112760621
Trimethylsilylacetylene | Chem-Impex | 1066-54-2 | MFCD00008569 | 98.220 | C5H10Si | 99.000 | C[Si](C)(C)C#C | 1kg | 112760621
Medchemexpress LLC Bis-propargyl-PEG6 100mg | 400775-35-1 | 358.43 g·mol⁻¹ | C18H30O7 | 100 MG
Bis-propargyl-PEG6 is a polyethylene glycol (PEG) linker bearing two terminal propargyl (alkyne) groups separated by a six-unit PEG spacer. It supplies clickable alkyne handles for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and is used to build bifunctional molecules such as PROTACs, polymer-linked multimers, and other bioconjugates. Molecular formula C18H30O7; MW 358.43 g·mol⁻1; CAS 400775-35-1.
- Provides two terminal alkyne handles for click chemistry.
- Six-unit PEG spacer improves aqueous solubility and flexibility.
- Well suited for PROTAC linker construction and bioconjugation.
- Compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Typically supplied as a 100 MG package; store at -20 °C for stability.
Medchemexpress LLC Propargyl-peg3-bromide | 203740-63-0 | 97.66% | 251.12 | 100 MG
Propargyl-PEG3-bromide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Peg-based protac linker
- Used in the synthesis of protacs
- Click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (Cuaac)
- Reacts with molecules containing azide groups
eMolecules 86256-18-0 | 4-Fluoro-3-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | MFCD06660255 | 210.128 | C8H6F4O2 | 98.000 | OCc1ccc(F)c(OC(F)(F)F)c1 | 1g | 562452484
4-Fluoro-3-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | 86256-18-0 | MFCD06660255 | 210.128 | C8H6F4O2 | 98.000 | OCc1ccc(F)c(OC(F)(F)F)c1 | 1g | 562452484
eMolecules 886501-26-4 | 4-Fluoro-3-(trifluoromethoxy)phenol | Apollo Scientific | MFCD06660257 | 196.101 | C7H4F4O2 | 95.000 | Oc1ccc(F)c(OC(F)(F)F)c1 | 1g | 562453217
4-Fluoro-3-(trifluoromethoxy)phenol | Apollo Scientific | 886501-26-4 | MFCD06660257 | 196.101 | C7H4F4O2 | 95.000 | Oc1ccc(F)c(OC(F)(F)F)c1 | 1g | 562453217
Medchemexpress LLC N-(Propargyl-PEG4)-biocytin | 2055042-71-0 | 98.0% | C28H46N4O9S | 250 MG
N-(Propargyl-PEG4)-biocytin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs consist of two different ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other the protein of interest, utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Supports targeted protein degradation
Medchemexpress LLC Propargyl-PEG6-alcohol | 944560-99-0 | 97.0% | 250 MG
Propargyl-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. This makes it suitable for various chemical synthesis applications.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Alkyne group for CuAAc reactions
- Used in the synthesis of PROTACs