Acetylides
Medchemexpress LLC 5-(Boc-amino)-1-pentanol | 75178-90-4 | MFCD01862955 | ≥97.0% | 203.28 g/mol | C10H21NO3 | 25 G
5-(Boc-amino)-1-pentanol is a Boc-protected amino alcohol used as a versatile linker and intermediate in organic synthesis and medicinal chemistry. It features a tert-butoxycarbonyl (Boc) protected amine and a primary hydroxyl group that permit orthogonal functionalization - the hydroxyl can be derivatized or replaced, and the Boc group can be removed under mild acidic conditions to reveal the free amine.
- Contains a Boc-protected amine and a primary hydroxyl.
- Enables orthogonal functionalization for multi-step syntheses.
- Hydroxyl group suitable for derivatization or conjugation reactions.
- Boc group deprotects under mild acidic conditions to yield free amine.
- High purity (≥97%) appropriate for research applications.
- Solid material stable at room temperature with defined solvent storage conditions.
Medchemexpress LLC Bis-propargyl-PEG11 | 1351373-49-3 | 99.79% | 578.69 | 250 MG
Bis-propargyl-PEG11 is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- PEG-based PROTAC linker.
- Can be used in the synthesis of PROTACs.
- Click chemistry reagent with an Alkyne group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide groups.
Medchemexpress LLC Bis-propargyl-PEG1 | 40842-04-4 | 98.0% | 138.16 | 100 MG
Bis-propargyl-PEG1 is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs. This click chemistry reagent contains an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- PEG-based PROTAC linker
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Suitable for PROTAC synthesis
Medchemexpress LLC Propargyl-PEG6-NHS ester | 2093153-99-0 | 98.0% | 445.46 g/mol | C20H31NO10 | 250 MG
Propargyl-PEG6-NHS ester is an alkyne-functionalized polyethylene glycol (PEG6) N-hydroxysuccinimide (NHS) ester used for bioconjugation and linker synthesis. It reacts with primary amines to form stable amide bonds and provides an alkyne handle suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
- Amine-reactive NHS ester for stable amide bond formation.
- Alkyne handle for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Peg6 spacer to improve solubility and reduce steric hindrance.
- High purity suitable for synthetic bioconjugation workflows.
- Available in small pack sizes for laboratory-scale synthesis.