Lignans and related compounds
Medchemexpress LLC Etoposide (Standard) | 33419-42-0 | 99.6% | 588.56 | 250 MG
Etoposide (Standard) is the analytical standard of Etoposide, intended for research and analytical applications. It functions as an anti-cancer chemotherapy agent by inhibiting topoisomerase II, which stops DNA replication. Additionally, Etoposide induces cell cycle arrest, apoptosis, and autophagy.
- Analytical standard for etoposide
- Intended for research and analytical applications
- Inhibits topoisomerase II
- Stops DNA replication
- Induces cell cycle arrest, apoptosis, and autophagy
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC Etoposide | 33419-42-0 | C29H32O13 | 10MG
Etoposide (Standard) is an analytical reference standard of the antineoplastic agent etoposide (CAS 33419-42-0). It is intended for research and analytical applications such as assay development, method validation, and quality control. The material has confirmed purity of 99.62% by HPLC and is supplied with supporting documentation for traceability.
- High purity reference material, 99.62% by HPLC.
- Intended for assay development and method validation.
- Suitable for quality control and analytical testing.
- Applicable to studies of topoisomerase II inhibition and related pharmacology.
- Provided with a certificate of analysis to support traceability.
Medchemexpress LLC N-demethyl lincomycin hydrochloride | 14600-41-0 | MFCD00008831 | >95.0% | 428.97 | C17H33ClN2O6S | 1 MG
N-demethyl lincomycin hydrochloride is the N-demethylated derivative of lincomycin supplied as the hydrochloride salt for research and analytical applications. It is provided as an impurity reference for impurity profiling and method development in analytical laboratories.
- Hydrochloride salt form for improved handling and solubility.
- Intended for use as an analytical standard and impurity reference.
- Applicable to HPLC and method development workflows.
- Molecular formula C17H33ClN2O6S and molecular weight 428.97 g/mol.
- Available in small-scale quantities suitable for analytical testing.
Medchemexpress LLC O-demethyl lenvatinib hydrochloride | 97.1% | 449.29 g/mol | C20H18Cl2N4O4 | 5 MG
O-demethyl lenvatinib hydrochloride is the O-demethylated metabolite of the kinase inhibitor lenvatinib, provided as a hydrochloride salt for research and analytical applications. It is intended as an analytical standard for in vitro studies, method development, and metabolite identification.
- Metabolite of lenvatinib for metabolite profiling and analytical reference.
- Hydrochloride salt form for improved stability and handling.
- High purity (97.1%) suitable for analytical workflows.
- Small 5 mg pack size ideal for method development and reference use.
- Molecular weight 449.29 g/mol and formula C20H18Cl2N4O4 for accurate calculations.
Medchemexpress LLC Podophyllotoxin glucoside | 16481-54-2 | 576.55 | 1 MG
Podophyllotoxin glucoside is a derivative of podophyllotoxin, exhibiting anti-tumor effects. It is suitable for research use and has been tested for cytotoxicity against human HeLa and KB cells.
- Exhibits anti-tumor effects
- Tested for cytotoxicity against human HeLa cells: ED50 of 21.8 μg/mL (after 4 days by trypan blue assay) and IC50 of 6.65 μM (after 72 hours by MTT assay)
- Tested for cytotoxicity against human KB cells: IC50 of 9.25 μM (after 72 hours by MTT assay)
AdipoGen Podophyllotoxin
Chemical. CAS 518-28-5. Formula C22H22O8. MW 414.4. Isolated from Podophyllum emodi rhizomes. Potent microtubule assembly inhibitor. Anticancer compound. Cell death inducer. DNA topoisomerase II inhibitor. Cell cycle inhibitor at the metaphase. Antiviral and antihelminthic.
Medchemexpress LLC Etoposide (Standard) | 33419-42-0 | 99.6% | 588.56 | 100 MG
Etoposide (Standard) is an analytical standard of Etoposide, intended for research and analytical applications. Etoposide is an anti-cancer chemotherapy agent that inhibits topoisomerase II, thereby stopping DNA replication. It induces cell cycle arrest, apoptosis, and autophagy.
- Serves as a reference standard for assays
- Suitable for qualitative, quantitative, and methodological research experiments (e.g., HPLC, GC, MS)
- Inhibits topoisomerase II
- Induces cell cycle arrest, apoptosis, and autophagy
Medchemexpress LLC Etoposide | 33419-42-0 | 99.9% | 588.56 | 25 MG
Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent that inhibits topoisomerase II, thereby stopping DNA replication. It induces cell cycle arrest, apoptosis, and autophagy, making it a valuable tool in cancer research and related studies.
- Inhibits topoisomerase II
- Stops DNA replication
- Induces cell cycle arrest
- Promotes apoptosis
- Triggers autophagy
- Used as an anti-cancer chemotherapy agent
Medchemexpress LLC Podophyllotoxin glucoside | 16481-54-2 | 576.55 | 5 MG
Podophyllotoxin glucoside is a podophyllotoxin derivative that has anti-tumor effects.
- Podophyllotoxin derivative
- Solid
- White to off-white color
- Has anti-tumor effects
Medchemexpress LLC Etoposide impurity 1 (Standard) | 23363-35-1 | 562.52 | 25 MG
Etoposide impurity 1, also known as Lignan P (Standard), is an analytical standard primarily intended for research and analytical applications. It serves as a reference standard, commonly utilized in various methodological research experiments such as High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), and Mass Spectrometry (MS).
- Intended for research and analytical applications
- Serves as a reference standard
- Commonly used in HPLC, GC and MS experiments
TARGETMOL CHEMICALS INC PICROPODOPHYLLOTOXIN 25MG
Also available in 1 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum) and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential antineoplastic activity. Picropodophyllotoxin (AXL 1717) specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors such as receptors for insulin epidermal growth factor platelet-derived growth factor fibroblast growth factor and mast/stem cell growth factor (KIT). This agent shows potent activity in the suppression o f tumor cell proliferation and the induction of tumor cell apoptosis. IGF1R a receptor tyrosine kinase overexpressed in a variety of human cancers plays a critical role in the growth and survival of many types of cancer cells. purity: 99%