Hydrobromides
Medchemexpress LLC Burixafor hydrobromide | 1191450-19-7 | 98.0% | 769.01 | 500 MG
Burixafor (TG-0054) hydrobromide is a potent CXCR4 antagonist with a pIC50 of 7.4. It inhibits the binding of CXCL12 to CXCR4, antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2, and blocks the downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction. Burixafor hydrobromide mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) from the bone marrow to the peripheral blood.
- Can be used for research on autologous hematopoietic stem cell transplantation (ASCT).
- Potent CXCR4 antagonist.
- Inhibits CXCL12 binding to CXCR4.
- Blocks Gαᵢ-mediated inhibitory effect on cAMP signal transduction.
- Mobilizes CD34+ hematopoietic stem/progenitor cells.
TARGETMOL CHEMICALS INC Galanthamine hydrobromide
Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors. Purity 99.19%
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 50 MG
Eletriptan hydrobromide (Eletriptan HBr) is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity, with Ki values of 0.92 nM and 3.14 nM, respectively. It is for research use only and not sold to patients.
- 5-HT1B and 5-HT1D receptor agonist
- Antimigraine activity
Medchemexpress LLC Arecoline | 63-75-2 | 50 MG
Arecoline is a naturally occurring, brain-penetrant, and orally active psychoactive alkaloid. It acts as a partial agonist of both nicotinic and muscarinic acetylcholine receptors. It has been observed to induce stimulation, alertness, anxiolysis, and anti-parasitic effects, and can also induce oxidative stress.
- Naturally brain-penetrant and orally active psychoactive alkaloid.
- Partial agonist of nicotinic and muscarinic acetylcholine receptors.
- Exhibits stimulation, alertness, anxiolysis, and anti-parasitic effects.
- High purity: 99.84%.
Medchemexpress LLC Galanthamine hydrobromide | 1953-04-4 | 99.9% | C17H22BrNO3 | 1 ML
Galanthamine hydrobromide is a selective, reversible, competitive, alkaloid AChE inhibitor (IC50 0.35 μM) and a potent allosteric potentiating ligand (APL) for human α3β4, α4β2, α6β4 nicotinic receptors (nAChRs). It is developed for Alzheimer's disease (AD) research.
- Selective, reversible, competitive, alkaloid AChE inhibitor.
- Potent allosteric potentiating ligand (APL) of human nAChRs.
- Developed for Alzheimer's disease (AD) research.
- Demonstrates 53-fold selectivity for AChE over butyrylcholinesterase.
- Inhibits Aβ 1-40 and Aβ 1-42 aggregation (50 μM).
- Protects against Aβ(1-40) and Aβ(1-42) toxicity in SH-SY5Y cells.
- Reduces Aβ(1-40)-induced cellular apoptosis.
- Reduces cognitive deficits in APP23 mice.
Medchemexpress LLC NAN-190 hydrobromide | 115338-32-4 | 99.1% | 474.39 | 10 MG
NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist, specifically a selective antagonist of 5-HT1A receptors. It is primarily used for research purposes and has been shown to reverse the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats.
- Serotonin receptor 5-HT antagonist
- Selective antagonist of 5-HT1A receptor
- Reverses catalepsy-improving effect of fluoxetine
- For research use only
eMolecules 62595-74-8 | 3-Bromopiperidine-2,6-dione | Synthonix - Stock | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 1g | 476497459
3-Bromopiperidine-2,6-dione | Synthonix - Stock | 62595-74-8 | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 1g | 476497459
Medchemexpress LLC S-(2-aminoethyl) methanethiosulfonate hydrobromide | 16599-33-0 | 97.9% | 25 MG
MTSEA hydrobromide is a sulfhydryl-reactive reagent that selectively modifies free cysteine residues to introduce a positively charged side chain roughly the size of lysine. It is used in biochemical and electrophysiological studies to probe cysteine accessibility and to introduce charge at engineered cysteine sites.
- Sulfhydryl-reactive reagent for targeted cysteine modification.
- High supplied purity of 97.9%.
- Molecular weight 236.15 g/mol; formula C3H10BrNO2S2.
- Available in small solid packs suitable for research use.
- Store sealed at -20°C; in solution store at -80°C for long-term stability.
- CAS number 16599-33-0 for unambiguous identification.
Apexbio Technology LLC Imetit dihydrobromide 32385-58-3 10mg
Imetit dihydrobromide (CAS 32385-58-3) is a potent high-affinity agonist of histamine H3 and H4 receptors demonstrating Ki values of 0 3 nM and 2 7 nM respectively Functionally it replicates histaminergic effects by inducing morphological changes in eosinophils with an EC50 of 25 nM Owing to its selective receptor activity Imetit dihydrobromide is widely employed in studies investigating allergic inflammatory processes including asthma as well as in research focused on central nervous system physiology and histamine-related pathways
Medchemexpress LLC Guvacoline hydrobrom 10mg | 17210-51-4 | 222.08 g·mol⁻1 | C7H12BrNO2 | 10 MG
Guvacoline hydrobromide is the hydrobromide salt of guvacoline, a pyridine alkaloid that acts as a weak full agonist at atrial and ileal muscarinic acetylcholine receptors. This research-grade solid is provided for in vitro pharmacology and receptor-binding studies.
- High purity (96.09%) research-grade material.
- Molecular weight 222.08 g·mol⁻1; formula C7H12BrNO2.
- Suitable for muscarinic receptor pharmacology and neuropharmacology assays.
- Supplied as a 10 mg solid for small-scale experimental use.