Hydrobromides
Medchemexpress LLC (RS)-AMPA hydrobromide | 171259-81-7 | MFCD00055183 | 99.5% | 267.08 g/mol | C7H11BrN2O4 | 1 MG
(RS)-AMPA hydrobromide is the racemic hydrobromide salt of AMPA, a selective agonist of AMPA-type ionotropic glutamate receptors. It is intended for research use in receptor pharmacology, electrophysiology, and biochemical assays that require a water-soluble AMPA agonist.
- Selective AMPA receptor agonist for glutamatergic signaling studies.
- Hydrobromide salt form improves water solubility.
- High purity suitable for analytical and biological experiments.
- Available in small milligram pack sizes for laboratory use.
- Applicable to electrophysiology, pharmacology, and biochemical assays.
Medchemexpress LLC NAN-190 hydrobromide | 115338-32-4 | 99.1% | 474.39 | 100 MG
NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist and a selective antagonist of 5-HT1A. It is intended for research use only.
- Appearance: Solid
- Color: Light yellow to yellow
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month
Medchemexpress LLC Pifithrin-α hydrobromide | 63208-82-2 | C16H19BrN2OS | 100 MG
Pifithrin-α hydrobromide is a p53 inhibitor that blocks its transcriptional activity and prevents cells from apoptosis. It also acts as an aryl hydrocarbon receptor (AhR) agonist. It is a water-soluble compound that can suppress p53 protein transcription and block glucose oxidase (GOX)-induced Bcl-2 protein reduction and Bax increase.
- Blocks transcriptional activity of p53
- Prevents cells from apoptosis
- Acts as an aryl hydrocarbon receptor (AhR) agonist
- Suppresses p53 protein transcription
- Blocks GOX-induced Bcl-2 protein reduction and Bax increase
- Induces AhR DNA binding complex formation
- Activates reporter activity
- Up-regulates the classic AhR target gene CYP1A1
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 100 MG
Eletriptan hydrobromide is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity, exhibiting Ki values of 0.92 nM and 3.14 nM, respectively. It is intended for research use only. In vivo studies have shown that eletriptan hydrobromide dose-dependently reduces carotid blood flow in anesthetized dogs and inhibits dural plasma protein extravasation in anesthetized rats.
- Functions as a 5-HT1B and 5-HT1D receptor agonist.
- Exhibits Ki values of 0.92 nM for 5-HT1B receptor.
- Exhibits Ki values of 3.14 nM for 5-HT1D receptor.
- Dose-dependently reduces carotid blood flow in anesthetized dogs.
- Inhibits dural plasma protein extravasation in anesthetized rats.
- Completely inhibits plasma protein extravasation from the dura mater at 100 μg/kg.
Medchemexpress LLC Burixafor (hydrobromide) | 1191450-19-7 | 98.0% | 769.01 | 50 MG
Burixafor hydrobromide is a potent CXCR4 antagonist with a pIC50 of 7.4. It inhibits CXCL12 binding to CXCR4, antagonizes Gαᵢ and β-arrestin2 recruitment, and blocks downstream Gαᵢ-mediated effects on cAMP signal transduction. This compound mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) for research on autologous hematopoietic stem cell transplantation (ASCT).
- Potent CXCR4 antagonist with a pIC50 of 7.4.
- Inhibits CXCL12 binding to CXCR4.
- Antagonizes CXCL12-induced Gαᵢ and β-arrestin2 recruitment.
- Blocks downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction.
- Mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC).
- Useful for research on autologous hematopoietic stem cell transplantation (ASCT).
Medchemexpress LLC Dihydro-β-erythroidine hydrobromide | 29734-68-7 | >98.0% | 356.25 g·mol⁻¹ | C16H22BrNO3 | 5 MG
Dihydro-β-erythroidine hydrobromide is a research reagent that acts as a competitive antagonist of neuronal nicotinic acetylcholine receptors, with preferential activity at α4β2 and α4β4 subtypes. Supplied as the hydrobromide salt, it is used in electrophysiology, receptor pharmacology, and in vivo studies to selectively inhibit nAChR-mediated responses.
- High purity (≥98% by HPLC).
- Selective antagonist for α4β2 and α4β4 nicotinic receptors.
- Suitable for in vitro and in vivo pharmacology studies.
- Supplied as hydrobromide salt for improved stability and solubility.
- Available in small research package sizes (1 mg, 5 mg, 10 mg).
- Documented identifiers include CAS 29734-68-7 and molecular weight 356.25 g·mol⁻¹.
eMolecules 180695-79-8 | N-Boc-4-bromopiperidine | ChemScene | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 100g | 536842064
N-Boc-4-bromopiperidine | ChemScene | 180695-79-8 | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 100g | 536842064
Medchemexpress LLC Oxidopamine (hydrobromide) | 636-00-0 | 99.4% | 200 MG
Oxidopamine (hydrobromide) | 636-00-0 | 99.4% | 200 MG
eMolecules 180695-79-8 | 1-Boc-4-bromopiperidine | Accela ChemBio (ASD) | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 5g | 452412445
1-Boc-4-bromopiperidine | Accela ChemBio (ASD) | 180695-79-8 | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 5g | 452412445
Apexbio Technology LLC A 61603 hydrobromide 107756-30-9 5mg
A 61603 hydrobromide (CAS 107756-30-9) is a potent and highly selective agonist of the 1A-adrenergic receptor one of the 1-adrenergic receptor subtypes involved in cellular growth and proliferation Compared to its activity at 1B- and 1D-adrenergic receptors A 61603 demonstrates approximately 35-fold higher potency for 1A-AR In cellular assays it robustly induces phosphoinositide hydrolysis in 1A-AR-expressing fibroblasts (pEC50 8 24) and in neonatal rat cardiomyocytes it increases calcium transient frequency in a dose-dependent manner (EC50 6 9 nM) In vascular models A 61603 markedly elevates perfusion pressure demonstrating significantly greater efficacy than noradrenaline This compound serves as a valuable tool for delineating 1A-AR-mediated signaling and vascular regulation
eMolecules 62595-74-8 | 3-Bromopiperidine-2,6-dione | ChemScene | MFCD11053059 | 192.012 | C5H6BrNO2 | 95.000 | BrC1CCC(=O)NC1=O | 250mg | 791178655
3-Bromopiperidine-2,6-dione | ChemScene | 62595-74-8 | MFCD11053059 | 192.012 | C5H6BrNO2 | 95.000 | BrC1CCC(=O)NC1=O | 250mg | 791178655
Medchemexpress LLC Halofuginone hydrobromide | 64924-67-0 | 495.59 | 25 MG
Halofuginone (hydrobromide) (Standard) is the analytical standard of Halofuginone (hydrobromide). It is a Febrifugine derivative and a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. This product is intended for research and analytical applications.
- Analytical standard for Halofuginone (hydrobromide)
- Competitive prolyl-tRNA synthetase inhibitor (Ki of 18.3 nM)
- Specific inhibitor of type-I collagen synthesis
- Attenuates osteoarthritis (OA) by inhibiting TGF-β activity
- Potent pulmonary vasodilator (activates Kv channels and blocks voltage-gated, receptor-operated and store-operated Ca2+ channels)
- Anti-malaria, anti-inflammatory, anti-cancer, and anti-fibrosis effects
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC Guvacoline hydrobrom 50mg | 17210-51-4 | 222.08 g·mol⁻¹ | C7H12BrNO2 | 50 MG
Guvacoline hydrobromide is a research-grade pyridine alkaloid that acts as a weak full agonist of atrial and ileal muscarinic acetylcholine receptors (mAChR). Supplied as a white to off-white solid with reported purity of 96.09%, it is used in receptor pharmacology and biochemical studies and is available in small laboratory pack sizes.
- White to off-white solid suitable for laboratory use.
- Reported purity of 96.09%.
- Molecular weight 222.08 g·mol⁻¹.
- Available in small pack sizes including 50 MG for bench-scale experiments.
- Store sealed at 4°C away from moisture and light; in solvent keep at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC SCH-202676 hydrobromide | 265980-25-4 | 96.81% | 348.26 | 1 MG
SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors (GPCRs) and adenosine receptor (AR). It exhibits antiviral activity and inhibits 3CLpro in a time-dependent manner with an IC50 value of 0.655 μM.
- Allosteric modulator of G protein-coupled receptors (GPCRs)
- Allosteric modulator of adenosine receptor (AR)
- Antiviral activity
- Inhibits 3CLpro in a time-dependent manner
- IC50 value of 0.655 μM against 3CLpro
Medchemexpress LLC BC-11 hydrobromide | 443776-49-6 | 99.0% | 290.97 | 50 MG
BC-11 hydrobromide is a selective TMPRSS2 inhibitor, which is a crucial host cellular factor for viral entry and SARS-CoV-2 pathogenesis. It also acts as a selective urokinase (uPA) inhibitor with an IC50 of 8.2 μM. This compound exhibits cytotoxicity towards triple-negative MDA-MB231 breast cancer cells, making it relevant for research on viral infections and cancer.
- A selective TMPRSS2 inhibitor.
- A selective urokinase inhibitor.
- Cytotoxic to triple-negative MDA-MB231 breast cancer cells.
- Used in research on viral infections and cancer.