Hydrobromides
Medchemexpress LLC Arecoline | 63-75-2 | 100 MG
Arecoline is a naturally brain-penetrant and orally active psychoactive alkaloid. It functions as a partial agonist of nicotinic and muscarinic acetylcholine receptors. It has been observed to exhibit stimulation, alertness, anxiolysis, and anti-parasitic effects. Research indicates it can also induce oxidative stress.
- Partial agonist of nicotinic and muscarinic acetylcholine receptors
- Exhibits stimulation and alertness
- Demonstrates anxiolysis and anti-parasitic effects
- Induces generation of reactive oxygen species
- Causes cell cycle arrest at G1/G0 phase in HaCaT cells
- Upregulates hemeoxygenase-1, ferritin light chain, glucose-6-phosphate dehydrogenase, glutamate-cysteine ligase catalytic subunit, and glutathione reductase expression
- Alleviates anxiety and depression in CFA-induced mice
Apexbio Technology LLC NAN-190 hydrobromide 115338-32-4 200mg
NAN-190 hydrobromide (CAS 115338-32-4) is a selective antagonist of the serotonin 5-HT1A receptor functioning by inhibiting receptor-mediated signal transduction pathways In receptor binding assays NAN-190 hydrobromide demonstrates high affinity for 5-HT1A receptors and modulates neurotransmitter release This compound is frequently employed in neurobiology and psychiatric disorder studies to investigate 5-HT1A-related mechanisms serving as a valuable tool for elucidating serotonergic signaling and its implications in neural function and pathology
Medchemexpress LLC Guvacoline hydrobrom 25mg | 17210-51-4 | 25 MG
Guvacoline hydrobromide is the hydrobromide salt of guvacoline, a pyridine alkaloid found in Areca triandra. It is used as a research reagent and functions as a weak full agonist of atrial and ileal muscarinic acetylcholine receptors (mAChR).
- Acts as a weak full agonist of atrial and ileal muscarinic receptors.
- White to off-white solid physical form.
- Molecular formula C7H12BrNO2 and molecular weight 222.08.
- Purity typically around 96.09% by HPLC.
- Store sealed at 4°C and protect from moisture and light; in solution store at -80°C for long-term.
- Supplied in small milligram pack sizes for laboratory research.
Medchemexpress LLC (RS)-AMPA hydrobromide | 171259-81-7 | MFCD00055183 | 99.5% | 267.08 g·mol⁻¹ | C7H11BrN2O4 | 5 MG
(RS)-AMPA hydrobromide is a research-grade glutamate analogue that acts as a potent, selective agonist of AMPA-type ionotropic glutamate receptors. Supplied as a solid hydrobromide salt with high purity, it is intended for use in neuropharmacology, electrophysiology, and receptor pharmacology studies. The compound is soluble in DMSO and water (sonication recommended) and should be stored protected from moisture under refrigerated or low-temperature conditions as specified by the supplier.
- Potent, selective agonist of AMPA receptors.
- Hydrobromide salt increases aqueous solubility.
- High purity suitable for research and analytical applications.
- Soluble in DMSO and water; sonication recommended.
- Stable when stored sealed and protected from moisture.
- Provided in small milligram quantities for experimental use.
eMolecules 180695-79-8 | N-Boc-4-bromopiperidine | ChemScene | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 1g | 894452969
N-Boc-4-bromopiperidine | ChemScene | 180695-79-8 | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 1g | 894452969
Medchemexpress LLC 2-iminobiotin hydrobromide | 76985-52-9 | 98.0% | 324.24 g·mol⁻1 | C10H18BrN3O2S | 1 ML
2-Iminobiotin hydrobromide is a biotin analog and a reversible inhibitor of nitric oxide synthases used in research to probe NO signaling and neuroprotection. It is supplied as a 10 mM solution in DMSO (1 mL) and has reported Ki values of 21.8 μM for murine iNOS and 37.5 μM for rat n-cNOS. For research use only; not for human or therapeutic applications.
- Biotin analog that reversibly inhibits nitric oxide synthases (NOS).
- Reported Ki: 21.8 μM (murine iNOS) and 37.5 μM (rat n-cNOS).
- Supplied as 10 mM solution in DMSO, 1 mL vial.
- Molecular weight 324.24 g·mol⁻1; formula C10H18BrN3O2S.
- Purity: 98.0%.
- Suitable for research on NO signaling, immunology, and neuroprotection.
Medchemexpress LLC Fatostatin hydrobromide | 298197-04-3 | MFCD00760867 | 99.52% | C18H19BrN2S | 25 MG
Fatostatin hydrobromide (125B11 hydrobromide) is a specific inhibitor of SREBP activation. It impairs the activation of SREBP-1 and SREBP-2 by binding to SCAP (SREBP cleavage-activating protein), which inhibits the ER-Golgi translocation of SREBPs. This action leads to a decrease in the transcription of lipogenic genes in cells.
- Specific inhibitor of SREBP activation.
- Impairs activation of SREBP-1 and SREBP-2.
- Inhibits ER-Golgi translocation of SREBPs.
- Decreases transcription of lipogenic genes.
- Exhibits antitumor properties.
- Lowers hyperglycemia in ob/ob mice.
Medchemexpress LLC Galanthamine hydrobromide (Galantamine hydrobromide) | 1953-04-4 | 99.9% | C17H22BrNO3 | 500 MG
Galanthamine hydrobromide is a selective, reversible, competitive, alkaloid AChE inhibitor with an IC50 of 0.35 μM. It also acts as a potent allosteric potentiating ligand (APL) for human α3β4, α4β2, and α6β4 nicotinic receptors (nAChRs). This compound is primarily developed for research into Alzheimer's disease (AD).
- Selective, reversible, competitive alkaloid AChE inhibitor
- Potent allosteric potentiating ligand of human α3β4, α4β2, α6β4 nicotinic receptors (nAChRs)
- Developed for Alzheimer's disease (AD) research
- IC50 of 0.35 μM for AChE