Hydrobromides
Medchemexpress LLC Fatostatin hydrobromide | 298197-04-3 | MFCD00760867 | 99.52% | C18H19BrN2S | 25 MG
Fatostatin hydrobromide (125B11 hydrobromide) is a specific inhibitor of SREBP activation. It impairs the activation of SREBP-1 and SREBP-2 by binding to SCAP (SREBP cleavage-activating protein), which inhibits the ER-Golgi translocation of SREBPs. This action leads to a decrease in the transcription of lipogenic genes in cells.
- Specific inhibitor of SREBP activation.
- Impairs activation of SREBP-1 and SREBP-2.
- Inhibits ER-Golgi translocation of SREBPs.
- Decreases transcription of lipogenic genes.
- Exhibits antitumor properties.
- Lowers hyperglycemia in ob/ob mice.
Medchemexpress LLC Galanthamine hydrobromide (Galantamine hydrobromide) | 1953-04-4 | 99.9% | C17H22BrNO3 | 500 MG
Galanthamine hydrobromide is a selective, reversible, competitive, alkaloid AChE inhibitor with an IC50 of 0.35 μM. It also acts as a potent allosteric potentiating ligand (APL) for human α3β4, α4β2, and α6β4 nicotinic receptors (nAChRs). This compound is primarily developed for research into Alzheimer's disease (AD).
- Selective, reversible, competitive alkaloid AChE inhibitor
- Potent allosteric potentiating ligand of human α3β4, α4β2, α6β4 nicotinic receptors (nAChRs)
- Developed for Alzheimer's disease (AD) research
- IC50 of 0.35 μM for AChE
eMolecules 31582-45-3 | 2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL METHACRYLATE | AstaTech | MFCD06200811 | 225.332 | C13H23NO2 | 95.000 | CC(=C)C(=O)OC1CC(C)(C)NC(C)(C)C1 | 5g | 818504081
2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL METHACRYLATE | AstaTech | 31582-45-3 | MFCD06200811 | 225.332 | C13H23NO2 | 95.000 | CC(=C)C(=O)OC1CC(C)(C)NC(C)(C)C1 | 5g | 818504081
eMolecules 180695-79-8 | N-Boc-4-bromopiperidine | ChemScene | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 100g | 536842064
N-Boc-4-bromopiperidine | ChemScene | 180695-79-8 | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 100g | 536842064
eMolecules 62595-74-8 | 3-bromopiperidine-2,6-dione | Pharmablock | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 25g | 642185380
3-bromopiperidine-2,6-dione | Pharmablock | 62595-74-8 | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 25g | 642185380
Apexbio Technology LLC 6-Hydroxydopamine hydrobromide(Synonyms: Oxidopamine hydrobromide, 6-OHDA hydrobromide, 6-Hydroxydopamine HBr), 50mg, CAS: 636-00-0.
6-Hydroxydopamine hydrobromide (CAS 636-00-0) commonly referred to as 6-OHDA hydrobromide is a catecholamine-derived neurotoxin frequently used in neuroscience research to induce selective dopaminergic neuronal degeneration Upon administration it generates intracellular reactive oxygen species (ROS) activating apoptotic pathways via caspase-3 -8 and -9 as demonstrated in PC12 cell studies In rodent models targeted injection into substantia nigra striatum or medial forebrain bundle leads to loss of tyrosine hydroxylase-positive neurons and resultant locomotor dysfunction resembling symptoms observed in Parkinson s disease Consequently it serves as a valuable tool for elucidating dopaminergic dysfunction mechanisms and evaluating therapeutic candidates
Medchemexpress LLC Pyrithiamine hydrobromide | 534-64-5 | 96.6% | 10MG
Pyrithiamine hydrobromide | 534-64-5 | 96.6% | 10MG
Medchemexpress LLC Dihydro-β-erythroidine hydrobromide | 29734-68-7 | >98.0% | 356.25 g·mol⁻¹ | C16H22BrNO3 | 5 MG
Dihydro-β-erythroidine hydrobromide is a research reagent that acts as a competitive antagonist of neuronal nicotinic acetylcholine receptors, with preferential activity at α4β2 and α4β4 subtypes. Supplied as the hydrobromide salt, it is used in electrophysiology, receptor pharmacology, and in vivo studies to selectively inhibit nAChR-mediated responses.
- High purity (≥98% by HPLC).
- Selective antagonist for α4β2 and α4β4 nicotinic receptors.
- Suitable for in vitro and in vivo pharmacology studies.
- Supplied as hydrobromide salt for improved stability and solubility.
- Available in small research package sizes (1 mg, 5 mg, 10 mg).
- Documented identifiers include CAS 29734-68-7 and molecular weight 356.25 g·mol⁻¹.
Abcam Arecoline hydrobromide, Muscarinic receptor agonist, 250MG
MW 236.11 Da, Purity >98%. Muscarinic receptor agonist (EC₅₀ values are 7 (M₁), 95 (M₂), 11 (M₃), 410 (M₄) and 69 nM (M₅)). Natural alkaloid. Induces decreased blood-brain barrier permeability.
The product is subject to the following: Abcam Restricted Use Statement
Hyoscyamine HBr, MP Biomedicals
CAS: 306-03-6 Molecular Formula: C17H24BrNO3 Molecular Weight (g/mol): 370.287 InChI Key: VZDNSFSBCMCXSK-BXSBZORQSA-N Synonym: hyoscyamine hydrobromide,daturine hydrobromide,unii-iwt50p9s79,l-hyoscyamine hydrobromide,hyoscyamine hydrobromide usp,--atropine hydrobromide,c17h23no3.hbr,1alphah,5alphah-tropan-3alpha-ol--tropate ester hydrobromide,unii-6vkw7r97zu component vzdnsfsbcmcxsk-pgqienjjsa-n PubChem CID: 9929278 IUPAC Name: [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate;hydrobromide SMILES: CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.Br