Hydrochlorides
Medchemexpress LLC Icotinib hydrochloride | 1204313-51-8 | C22H22ClN3O4 | 25 MG
Icotinib hydrochloride is a potent and specific EGFR inhibitor that is CNS-penetrant. It is effective against wild-type and various mutant EGFR forms, including EGFRL858R, EGFRL858R/T790M, EGFRT790M, and EGFRL861Q. This compound also functions as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Potent and specific EGFR inhibitor
- CNS-penetrant
- Inhibits mutant EGFR forms: EGFRL858R, EGFRL858R/T790M, EGFRT790M, and EGFRL861Q
- Click chemistry reagent with an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Cayman Chemical Terbinafine hydrochloride
A broad-spectrum antifungal agent; has activity against T. rubrum, T. metagrophytes, T. verrucosum, E. floccosum, M. canis, A. fumigatus, and S. schenckii (MIC50s = 0.003-0.8 μg/ml); selectively inhibits C. albicans squalene epoxidase over rat liver epoxidase (IC50s = 0.03 and 77 μM, respectively); induces cell cycle arrest at the G0/G1 phase in COLO 205 tumor cells and HUVECs from 90-120 μM
eMolecules 5407-57-8 | 1,2-ETHANEDIAMINE,N1-(7-CHLORO-4-QUINOLINYL) | AstaTech | MFCD02179802 | 221.690 | C11H12ClN3 | 95.000 | NCCNc1ccnc2cc(Cl)ccc12 | 1g | 282982525
1,2-ETHANEDIAMINE,N1-(7-CHLORO-4-QUINOLINYL) | AstaTech | 5407-57-8 | MFCD02179802 | 221.690 | C11H12ClN3 | 95.000 | NCCNc1ccnc2cc(Cl)ccc12 | 1g | 282982525
Medchemexpress LLC VU-1545 | 890764-63-3 | 99.0% | 402.38 | 100 MG
VU-1545 is a metabotropic glutamate receptor 5 positive allosteric modulator (mGluR5 PAM) with a Ki of 156 nM and an EC50 of 9.6 nM.
- Promotes AKT activation at concentrations of 0.1 and 1.0 μM.
- Neuroprotective in a mouse model of Huntington's disease.
- For research use only, not for sale to patients.
Medchemexpress LLC SB-399885 hydrochloride | 402713-81-9 | 98.3% | 482.81 g/mol | C18H22Cl3N3O4S | 100 MG
SB-399885 hydrochloride is a research-grade small molecule that functions as a selective 5-HT6 receptor antagonist for laboratory pharmacology and neuroscience studies. It is supplied as a solid reagent and should be handled and stored according to standard laboratory safety practices.
- Acts as a selective 5-HT6 receptor antagonist
- Suitable for in vitro and in vivo pharmacology studies
- Supplied as a solid with reported purity of 98.3%
- Molecular weight 482.81 g/mol; CAS 402713-81-9
- Available in multiple pack sizes for dose-ranging experiments
- For research use only; not for human or clinical use
Medchemexpress LLC ZT 52656A hydrochloride | 115730-24-0 | 100.0% | 390.87 g/mol | C19H26ClF3N2O | 1 MG
ZT 52656A hydrochloride is the hydrochloride salt of a selective kappa opioid receptor agonist supplied for laboratory research. It is used to investigate kappa-mediated analgesia, including prevention or alleviation of ocular pain, and is intended for preclinical in vitro and in vivo studies. Not for human or clinical use.
- Selective kappa opioid receptor agonist.
- Used in ocular pain models to assess analgesic effects.
- High purity (99.98%) suitable for research applications.
- Solid, white to off-white physical form.
- Hydrochloride salt for improved stability and solubility.
- Available in small research pack sizes for preclinical work.
![Medchemexpress LLC N-cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide, monohydrochloride | 1309976-62-2 | 98.9% | 330.78 g·mol⁻¹ | C18H16ClFN2O | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241376.png-250.jpg)
Medchemexpress LLC N-cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide, monohydrochloride | 1309976-62-2 | 98.9% | 330.78 g·mol⁻¹ | C18H16ClFN2O | 50 MG
VU0360172 hydrochloride is a research-grade small molecule and a potent, selective positive allosteric modulator of the metabotropic glutamate receptor 5 (mGlu5). Supplied as a solid for in vitro and in vivo pharmacology studies, it is characterized by nanomolar potency and high chemical purity.
- Selective mGlu5 PAM with EC50 = 16 nM and Ki = 195 nM.
- High purity suitable for research use (≈98.9%).
- Solid form, convenient for storage and formulation.
- Molecular weight 330.78 g·mol⁻¹; formula C18H16ClFN2O.
- Recommended sealed storage away from moisture at low temperature.
Medchemexpress LLC Co 101244 hydrochloride | 193356-17-1 | 99.9% | 377.90 g·mol⁻1 | C21H28ClNO3 | 1 ML
Co 101244 hydrochloride is a research-grade NMDA receptor antagonist selective for NR2B-containing receptor subtypes. It is used as a pharmacological tool in electrophysiology and biochemical studies to probe NMDA receptor function. The compound is available as a solid and as a 10 mM solution in DMSO for experimental use.
- Selective antagonist of NR2B-containing NMDA receptors.
- Provided as 10 mM solution in DMSO (1 mL) for immediate use.
- High reported purity suitable for research applications.
- Light yellow solid form for storage and handling.
- Useful in preclinical electrophysiology and pharmacology studies.
![Medchemexpress LLC N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide | 1135243-19-4 | MFCD18086889 | 99.8% | 432.52 | C18H20N6O3S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242004.png-250.jpg)
Medchemexpress LLC N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide | 1135243-19-4 | MFCD18086889 | 99.8% | 432.52 | C18H20N6O3S2 | 10 MG
VU 0255035 is a selective, competitive antagonist of the M1 muscarinic acetylcholine receptor used in preclinical research on central nervous system disorders. The compound (CAS 1135243-19-4) has molecular formula C18H20N6O3S2 and is supplied as a high-purity research-grade material for in vitro and in vivo pharmacology.
- Selective M1 receptor antagonism for pharmacological and mechanistic studies.
- High chemical purity suitable for analytical and biological assays.
- Available in multiple small-quantity formats for flexibility in dosing and screening.
- Suitable for both in vitro and in vivo experimental applications.
- Stable when stored under recommended conditions for research use.
Medchemexpress LLC T-3775440 hydrochloride | 1422535-52-1 | 99.1% | 346.85 g/mol | C18H23ClN4O | 10 MG
T-3775440 hydrochloride is the hydrochloride salt of T-3775440, an irreversible lysine-specific demethylase 1 (LSD1) inhibitor used in biochemical and cellular research. It has a reported IC50 of 2.1 nM and is supplied as a solid salt for assay and mechanistic studies.
- Irreversible LSD1 inhibitor with reported IC50 = 2.1 nM.
- Hydrochloride salt form suitable for biochemical and cell-based assays.
- High purity suitable for research use (reported purity 99.13%).
- Molecular formula C18H23ClN4O; molecular weight 346.85 g/mol.
- Packaged in small research quantities for assay development and validation.
Medchemexpress LLC T-3775440 hydrochloride | 1422535-52-1 | 99.1% | 346.85 g/mol | C18H23ClN4O | 50 MG
T-3775440 hydrochloride is an irreversible inhibitor of lysine-specific histone demethylase 1 (LSD1) with low-nanomolar potency. It is provided as a high-purity research reagent for biochemical and cellular studies of epigenetic regulation.
- Irreversible LSD1 inhibition with an IC50 of ~2.1 nM.
- High chemical purity suitable for research use.
- Available in small-scale quantities for screening and mechanistic studies.
- Useful for biochemical assays and cellular models of epigenetic regulation.
- Provided as a hydrochloride salt to improve stability and solubility.
Medchemexpress LLC HBED dihydrochloride | 35369-53-0 | MFCD04113603 | ≥95.0% | 461.34 g·mol⁻¹ | C20H26Cl2N2O6 | 250 MG
HBED dihydrochloride (CAS 35369-53-0) is an orally active, hexadentate phenolic aminocarboxylate iron chelator used in biochemical and pharmacological research to model iron binding and to study iron-overload in preclinical systems. Supplied as a white to off-white solid dihydrochloride salt, it is characterized by formula C20H26Cl2N2O6 and molecular weight 461.34 g·mol⁻¹.
- Orally active hexadentate iron chelator.
- Useful for in vitro and in vivo iron chelation studies.
- White to off-white solid form, easy to handle and weigh.
- Molecular formula C20H26Cl2N2O6; molecular weight 461.34 g·mol⁻¹.
- High purity suitable for research applications (product documentation shows ≥95.0% with a reported 91.66% data-sheet variant).
Sigma Aldrich Fine Chemicals Biosciences 4-Methylmorpholine BioXtra, suitable for protein sequencing, >=99.5% (GC) | 109-02-4 | MFCD00006175 | 500ML
4-Methylmorpholine BioXtra, suitable for protein sequencing, >=99.5% (GC) | Purity: >=99.5% (GC) | Mol Wt: 101.15 | 109-02-4 | MFCD00006175 | 500ML
Medchemexpress LLC Co 101244 hydrochloride (PD 174494) | 193356-17-1 | 99.9% | 377.90 | C21H28ClNO3 | 50 MG
Co 101244 hydrochloride is the hydrochloride salt of a small-molecule NR2B-containing NMDA receptor antagonist supplied for research use. It is a light yellow to yellow solid with high purity and characterized molecular properties and storage/solubility data for in vitro and in vivo applications.
- Selective NR2B NMDA receptor antagonist useful for neuroscience research.
- High purity suitable for analytical and biological assays.
- Well-characterized solubility in DMSO for solution preparation.
- Stable when stored sealed at recommended temperatures.
- Available in multiple small-scale quantities for laboratory use.