Hydrochlorides
Medchemexpress LLC PXS-6302 hydrochloride | 2584947-79-3 | C10H11ClF3NO2S | 5 MG
PXS-6302 hydrochloride is an irreversible lysyl oxidase inhibitor that effectively targets multiple LOX enzymes, with IC50 values ranging from 0.3 μM to 3.7 μM. Its excellent skin penetrability facilitates the reduction of collagen deposition and significantly enhances the appearance of scars.
- Acts as an irreversible lysyl oxidase inhibitor
- Effective against various LOX enzyme types
- Exhibits excellent skin penetrability
- Reduces collagen deposition
- Significantly improves scar appearance
- High permeability observed in Caco-2 and MDCKII cell assays
- Inhibits LOX and reduces crosslinking in porcine injury models
- Topical application improves scar appearance in murine and porcine models
Apexbio Technology LLC Duloxetine HCl 136434-34-9 10mg
Duloxetine hydrochloride (CAS 136434-34-9) is a small molecule compound classified as a selective inhibitor of serotonin and norepinephrine reuptake By blocking the reabsorption of these neurotransmitters at the synaptic cleft duloxetine modulates serotonergic and noradrenergic signaling within the central nervous system This pharmacological action has rendered it a valuable tool in research models investigating neurochemical pathways involved in mood regulation pain perception and stress response Duloxetine HCl is commonly utilized in studies of depression anxiety and chronic pain to elucidate monoaminergic mechanisms and to evaluate therapeutic strategies targeting neurotransmitter reuptake
Medchemexpress LLC Erlotinib hydrochloride | 183319-69-9 | 50MG
Erlotinib hydrochloride | 183319-69-9 | 50MG
eMolecules 56440-28-9 | (S)-3-AMINOPYRROLIDIN-2-ONE HCL | MFCD08273939 | 1g
AstaTech | (S)-3-AMINOPYRROLIDIN-2-ONE HCL | 1g | 323601592 | F31053 | 95.000 | 56440-28-9 | MFCD08273939 | 136.580 | C4H9ClN2O
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eMolecules 1402576-61-7 | 7-(TRIFLUOROMETHYL)QUINOLIN-3-AMINE | AstaTech | MFCD28133454 | 212.175 | C10H7F3N2 | 95.000 | Nc1cnc2cc(ccc2c1)C(F)(F)F | 1g | 261435877
7-(TRIFLUOROMETHYL)QUINOLIN-3-AMINE | AstaTech | 1402576-61-7 | MFCD28133454 | 212.175 | C10H7F3N2 | 95.000 | Nc1cnc2cc(ccc2c1)C(F)(F)F | 1g | 261435877
eMolecules 1824276-00-7 | 3-(TRIFLUOROMETHYL)QUINOLIN-7-AMINE | AstaTech | MFCD28133472 | 212.175 | C10H7F3N2 | 95.000 | Nc1ccc2cc(cnc2c1)C(F)(F)F | 1g | 410711973
3-(TRIFLUOROMETHYL)QUINOLIN-7-AMINE | AstaTech | 1824276-00-7 | MFCD28133472 | 212.175 | C10H7F3N2 | 95.000 | Nc1ccc2cc(cnc2c1)C(F)(F)F | 1g | 410711973
Medchemexpress LLC Iso-H7 dihydrochloride | 140663-38-3 | 99.1% | 364.29 | 25 MG
Iso-H7 dihydrochloride is an inhibitor of protein kinase with IC50 values of 22 and 34 μM for PKC and PKA, respectively. It has a negative control effect on PKA in satellite cell myogenesis.
- Protein kinase inhibitor.
- Inhibits PKC (IC50 = 22 μM).
- Inhibits PKA (IC50 = 34 μM).
- Negative control of PKA on satellite cell myogenesis.
Medchemexpress LLC PIM-447 dihydrochloride | 1820565-69-2 | 99.8% | 513.38 | 1 ML
PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor, with K¡ values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects, and induces apoptosis.
- Potent, orally available, and selective pan-PIM kinase inhibitor.
- K¡ values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively.
- Displays dual antimyeloma and bone-protective effects.
- Induces apoptosis.
Medchemexpress LLC Erlotinib (hydrochloride) | 183319-69-9 | 99.9% | 1 G
Erlotinib hydrochloride is the hydrochloride salt of erlotinib, a small-molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase intended for research use. It inhibits purified EGFR kinase with an IC50 of 2 nM and contains an alkyne group enabling copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Inhibits EGFR kinase; IC50 = 2 nM.
- Contains an alkyne group for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- High purity (99.94%) suitable for analytical and research applications.
- Molecular formula C22H24ClN3O4, molecular weight 429.90.
- Solid, melting point 223-225 °C; recommended storage 4 °C (sealed).
- Typically supplied as a 1 g research pack.
Medchemexpress LLC Bay-6672 hydrochloride | 2247520-31-4 | 98.0% | 581.33 | C26H28BrCl2N3O3 | 5 MG
BAY-6672 hydrochloride is a research-grade small molecule antagonist of the human Prostaglandin F (FP) receptor with a reported IC50 of 11 nM. Supplied as the hydrochloride salt and characterized at high purity, it is intended for in vitro pharmacology and biochemical studies and is available as a solid or as a 10 mM solution in DMSO. For research use only; not for human or clinical use.
- Potent FP receptor antagonist (IC50 = 11 nM).
- High purity suitable for pharmacological assays.
- Available as solid mg quantities and as a 10 mM DMSO solution.
- Characterized molecular weight and formula for identification.
- Intended for in vitro research use only.
Medchemexpress LLC Naloxone (hydrochloride) (Standard) | 357-08-4 | 100.0% | 363.84 | 100 MG
Naloxone hydrochloride is an Opioid receptor antagonist that alleviates opioid-overdose-induced respiratory depression and may cause pulmonary edema and cardiac arrhythmias. It has a molecular weight of 363.84 and a chemical formula of C19H22ClNO4.
- Appears as a solid, white to off-white substance
- Soluble in water at 62.5 mg/mL (requires ultrasonic assistance)
- Soluble in DMSO at concentrations of 30 mg/mL or greater
- Typically shipped at room temperature within the continental US
- Store solid product at 4°C in sealed containers, away from moisture
- Store solutions in solvent at -80°C for up to 6 months or -20°C for 1 month
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
Medchemexpress LLC Ecopipam hydrochloride | 190133-94-9 | 99.5% | 350.28 | C19H21Cl2NO | 5 MG
Ecopipam hydrochloride is a potent, selective, orally active antagonist of dopamine D1 and D5 receptors used in biochemical and pharmacological research. It has nanomolar affinity and shows high selectivity versus other monoaminergic receptors, and is supplied in high-purity forms suitable for in vitro and in vivo studies.
- Potent, selective antagonist of dopamine D1 and D5 receptors.
- Nanomolar affinity supports sensitive pharmacological assays.
- Greater than 40-fold selectivity versus D2, D4, 5-HT, and α2a receptors.
- Suitable for preclinical studies of neuropsychiatric and metabolic disorders.
- Available as solid and as DMSO solution; provided at high purity.