Hydrochlorides
Medchemexpress LLC Vu 0255035 | 1135243-19-4 | 99.8% | 432.52 | C18H20N6O3S2 | 5 MG
VU 0255035 is a selective M1 muscarinic receptor antagonist used as a research tool to probe M1-mediated signaling and synaptic responses in neuronal preparations. It is supplied as a solid with high purity and is characterized by its molecular formula and weight; handle under recommended storage conditions for best stability.
- Selective M1 muscarinic receptor antagonist with demonstrated neuronal activity.
- High purity: 99.8%.
- Molecular weight 432.52; formula C18H20N6O3S2.
- Available in small research quantities, such as 5 mg.
- Supplied as a solid; store at 4°C and protect from light (in solvent: -80°C for long-term storage).
- Suitable as a pharmacological probe for electrophysiology and signaling assays.
Medchemexpress LLC N-(1,3-diphenylpyrazol-5-yl)-4-nitrobenzamide | 890764-36-0 | MFCD12546140 | 99.6% | 384.39 g/mol | C22H16N4O3 | 5 MG
VU-29 is a research small molecule that acts as a positive allosteric modulator of the metabotropic glutamate 5 (mGlu5) receptor. It potentiates mGlu5 signaling with high potency and selectivity, and is supplied for laboratory research in solid or solution formats.
- Positive allosteric modulator of mGlu5 with high potency (EC50 ≈ 9 nM).
- Selective for mGlu5 versus other metabotropic glutamate receptors.
- Reported high purity suitable for biochemical and cellular assays.
- Available as small solid quantities or as 10 mM solutions in DMSO for convenience.
- Chemical formula C22H16N4O3; molecular weight 384.39 g/mol.
Medchemexpress LLC GR 55562 hydrochloride | 172854-55-6 | 98.0% | 411.92 | 10 MG
GR 55562 hydrochloride is a selective 5-HT1B receptor antagonist. It can be used for the research of nerve disease. This product is for research use only and not sold to patients.
- Selective 5-HT1B receptor antagonist.
- Applicable for research on nerve disease.
Medchemexpress LLC Nitrocaramiphen (hydrochloride) | 98636-73-8 | MFCD00673872 | 99.6% | 370.87 | C18H27ClN2O4 | 10 MG
Nitrocaramiphen hydrochloride is a selective muscarinic M1 receptor antagonist for research use, commonly applied in pharmacology and neuroscience to probe cholinergic signaling. It blocks muscarine-induced hyperpolarization in muscle fibers and is supplied as a purified solid for in vitro assays.
- Selective muscarinic M1 receptor antagonist (Ki 5.5 nM).
- Inhibits muscarine-induced hyperpolarization in muscle fibers.
- High purity solid suitable for in vitro research (purity 99.6%).
- Compact supply size for small-scale studies (10 mg).
- Stable when stored sealed and protected from moisture.
Medchemexpress LLC CP 93129 dihydrochloride | 879089-64-2 | 99.0% | 288.17 g·mol⁻1 | C12H15Cl2N3O | 1 MG
CP 93129 dihydrochloride is a selective 5-HT1B receptor agonist supplied for research use. It is used in pharmacology and neuroscience studies, including investigations related to Parkinson's disease, and is provided as a high-purity solid suitable for analytical, in vitro, and in vivo applications.
- Selective 5-HT1B receptor agonist suitable for receptor pharmacology studies.
- High purity (99.0%) for consistent experimental results.
- Molecular weight 288.17 g·mol⁻1 and formula C12H15Cl2N3O for precise calculations.
- Off-white to light yellow solid for convenient handling and storage.
- Recommended storage at 4°C, sealed and protected from moisture and light.
- Available in small, accurately weighed milligram quantities for dosing and assays.
Apexbio Technology LLC Tirofiban hydrochloride monohydrate 150915-40-5 5mg
Tirofiban hydrochloride monohydrate (CAS 150915-40-5) is a small-molecule inhibitor targeting platelet glycoprotein IIb/IIIa receptors It is designed to reversibly antagonize the binding of fibrinogen to these receptors thereby inhibiting platelet aggregation and thrombus formation Tirofiban hydrochloride monohydrate exerts its biological activity primarily through selective reversible inhibition of glycoprotein IIb/IIIa-mediated platelet aggregation Based on these pharmacological properties tirofiban hydrochloride monohydrate holds research potential in antithrombotic therapy and the investigation of unstable angina and thrombus-associated cardiovascular conditions
Medchemexpress LLC Zm323881 hydrochloride | 193000-39-4 | C22H19ClFN3O2 | 25 MG
ZM323881 hydrochloride is a potent and selective VEGFR2 inhibitor with an IC50 of less than 2 nM. This anilinoquinazoline potently inhibits VEGFR2 (KDR) tyrosine kinase activity, showing excellent selectivity over other receptor tyrosine kinases. It inhibits VEGF-A-induced endothelial cell proliferation and VEGFR2 tyrosine phosphorylation.
- Potent and selective VEGFR2 inhibitor (IC50 < 2 nM)
- Inhibits VEGFR2 (KDR) tyrosine kinase activity
- Excellent selectivity over other receptor tyrosine kinases
- Inhibits VEGF-A-induced endothelial cell proliferation (IC50 = 8 nM)
- Inhibits VEGFR2 tyrosine phosphorylation
- Blocks activation of VEGFR-2, while sparing VEGFR-1, EGFR, PDGFR, and HGF receptor
- For research use only
Medchemexpress LLC IACS-9571 hydrochloride | 2319611-93-1 | 98.3% | 679.22 g/mol | C32H43ClN4O8S | 1 ML
IACS-9571 hydrochloride is a potent, selective small-molecule inhibitor of the bromodomain proteins TRIM24 and BRPF1. It is used in biochemical and cellular research to probe bromodomain function, assess target engagement, and study downstream epigenetic regulation in vitro and in cells.
- Potent TRIM24 inhibition (IC50 = 8 nM) and strong BRPF1 binding (Kd = 14 nM).
- Demonstrates cellular activity (EC50 ≈ 50 nM).
- High purity suitable for research applications (>98% reported by supplier).
- Available as a 10 mM solution in DMSO (1 mL) and as solid quantities for custom preparation.
- Molecular formula C32H43ClN4O8S; molecular weight 679.22 g/mol.
Medchemexpress LLC CCT365623 hydrochloride | 2126136-98-7 | 98.1% | 443.99 | C18H18ClNO4S3 | 10MM 1ML
CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor supplied as a high-purity research reagent. It is available as solids and as a 10 mM solution in DMSO for use in biochemical and cellular assays, with molecular weight 443.99 g/mol and chemical formula C18H18ClNO4S3. Typical applications include LOX inhibition studies, signaling pathway research, and preclinical investigations.
- High purity, 98.1%.
- Available as 10 mM solution in DMSO (1 mL) and as solids (5-100 mg).
- Soluble in DMSO; ultrasonic agitation may improve dissolution.
- Molecular weight 443.99 g/mol.
- Suitable for biochemical and cellular LOX inhibition assays.
- Provided with certificate of analysis for batch verification.
- CAS number 2126136-98-7 for unambiguous identification.
Medchemexpress LLC T-3775440 hydrochloride | 1422535-52-1 | 99.1% | 346.85 g/mol | C18H23ClN4O | 10 MG
T-3775440 hydrochloride is the hydrochloride salt of T-3775440, an irreversible lysine-specific demethylase 1 (LSD1) inhibitor used in biochemical and cellular research. It has a reported IC50 of 2.1 nM and is supplied as a solid salt for assay and mechanistic studies.
- Irreversible LSD1 inhibitor with reported IC50 = 2.1 nM.
- Hydrochloride salt form suitable for biochemical and cell-based assays.
- High purity suitable for research use (reported purity 99.13%).
- Molecular formula C18H23ClN4O; molecular weight 346.85 g/mol.
- Packaged in small research quantities for assay development and validation.
eMolecules 5407-57-8 | 1,2-ETHANEDIAMINE,N1-(7-CHLORO-4-QUINOLINYL) | AstaTech | MFCD02179802 | 221.690 | C11H12ClN3 | 95.000 | NCCNc1ccnc2cc(Cl)ccc12 | 1g | 282982525
1,2-ETHANEDIAMINE,N1-(7-CHLORO-4-QUINOLINYL) | AstaTech | 5407-57-8 | MFCD02179802 | 221.690 | C11H12ClN3 | 95.000 | NCCNc1ccnc2cc(Cl)ccc12 | 1g | 282982525
Medchemexpress LLC Cyclohexylpiperazine derivative | 172907-03-8 | 99.6% | 443.49 | 100 MG
Cyclohexylpiperazine derivative | 172907-03-8 | 99.6% | 443.49 | 100 MG
Medchemexpress LLC Zt 52656a hydrochloride | 115730-24-0 | MFCD00673899 | 100.0% | 390.87 g·mol⁻¹ | C19H26ClF3N2O | 100 MG
ZT 52656A hydrochloride is the hydrochloride salt of a selective kappa opioid receptor agonist used in research to investigate kappa-mediated analgesia and the prevention or alleviation of ocular pain. Supplied as a white to off-white solid for laboratory applications, it is intended for research use only and not for clinical or human use.
- Selective kappa opioid receptor agonist.
- High reported purity (99.98%).
- Molecular weight 390.87 g·mol⁻¹.
- White to off-white solid suitable for analytical and in vivo studies.
- Recommended storage: 4°C sealed; in solvent: -80°C up to 6 months, -20°C up to 1 month.
- Available in multiple package sizes, including 100 mg.
Medchemexpress LLC L-368,899 hydrochloride | 160312-62-9 | 99.97% | 591.23 | 100 MG
L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist. It has IC50s of 8.9 nM for rat uterus and 26 nM for human uterus oxytocin receptor. This compound is used as a tocolytic agent.
- Potent oxytocin receptor antagonist.
- Selective for oxytocin receptor.
- Orally bioavailable.
- Non-peptide structure.
- Used as a tocolytic agent.
- Less active on VP receptor in human liver and kidney, and rat liver and kidney.
- Exhibits similar pharmacokinetics in rats and dogs with a t1/2 of 2 hours after a single IV injection.
- Plasma clearance between 23 and 36 ml/min/kg in rats or dogs.
- Vdss values of 2.0 and 2.6 liters/kg for rats and 3.4 to 4.9 liters/kg for dogs.
- Oral bioavailabilities in rats: 14% (female) and 18% (male) at 5 mg/kg; 17% (female) and 41% (male) at 25 mg/kg.