Hydrochlorides
Medchemexpress LLC Ynt-185 | 1804978-81-1 | 98.5% | 615.74 | 1 ML
YNT-185 is a nonpeptide, selective orexin type-2 receptor (OX2R) agonist. It has EC50s of 0.028 μM for OX2R and 2.75 μM for OX1R. YNT-185 has been shown to ameliorate narcolepsy-cataplexy symptoms in mouse models. It is for research use only and not sold to patients.
- Selectively activates the orexin type-2 receptor
- Ameliorates narcolepsy-cataplexy symptoms in mouse models
- Increases wakefulness in mice
- Significantly increases wake time in a dose-dependent manner
Medchemexpress LLC Naloxone hydrochloride (standard) | 357-08-4 | 99.7% | 363.84 | 50 MG
Naloxone hydrochloride (Standard) is the analytical standard of Naloxone hydrochloride, intended for research and analytical applications. It functions as an antagonist of the Opioid receptor and is known to alleviate opioid-overdose-induced respiratory depression. This compound is a reference standard supplied for assay and is commonly used in qualitative, quantitative, and methodological research experiments.
- Used for research and analytical applications.
- Functions as an Opioid receptor antagonist.
- Alleviates opioid-overdose-induced respiratory depression.
- Suitable for HPLC, GC, and MS experiments.
- Reference standard grade for assay.
Medchemexpress LLC XE991 dihydrochloride | 122955-13-9 | 99.6% | 449.37 | 10 MG
XE991 dihydrochloride is a Kv7 (KCNQ) channels blocker. It potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current with IC50s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively. This compound is designed for research applications.
- Potent Kv7 (KCNQ) channels blocker
- Inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current
- Enhances [3H]ACh release from rat brain slices with an EC50 of 490 nM
- Demonstrates good in vivo potency and duration of action
- For research use only
Medchemexpress LLC L-368,899 hydrochloride | 160312-62-9 | 100.0% | 591.23 | 10 MG
L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist. It has IC50s of 8.9 nM for rat uterus oxytocin receptor and 26 nM for human uterus oxytocin receptor. It is used as a tocolytic agent.
- Potent oxytocin receptor antagonist
- Selective action
- Orally bioavailable
- Non-peptide structure
- IC50s of 8.9 nM for rat uterus oxytocin receptor and 26 nM for human uterus oxytocin receptor
- Used as a tocolytic agent
- Soluble in DMSO (100 mg/mL)
- Soluble in H2O (5 mg/mL)
- Storage at 4°C sealed, away from moisture
- In solvent storage at -80°C for 2 years or -20°C for 1 year
Medchemexpress LLC Prazosin hydrochloride | 19237-84-4 | 99.89% | 500 MG
Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist, primarily used for research into high blood pressure and alcohol use disorders. It potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC50 of 0.15 nM, and also inhibits organic cation transporters OCT-1 and OCT-3 with IC50s of 1.8 and 13 μM, respectively.
- CNS-active α1-adrenergic receptor antagonist
- Potently inhibits norepinephrine (NE)-stimulated 45Ca efflux
- Inhibits organic cation transporters OCT-1 and OCT-3
- Inhibits proliferation, migration, and invasion of U251 and U87 cells, and promotes apoptosis via the PI3K/AKT/mTOR signaling pathway
- Peripheral administration can suppress central α1-adrenergic-mediated hyperexcitability and stress-induced anxiety
Medchemexpress LLC ZM323881 (hydrochloride) | 193000-39-4 | 99.6% | 411.86 | 10 MG
ZM323881 (hydrochloride) | 193000-39-4 | 99.6% | 411.86 | 10 MG
Medchemexpress LLC Doxepin impurity 1 (hydrochloride) | 4504-96-5 | 25mg
Doxepin impurity 1 hydrochloride is an impurity of Doxepin (HY-B0725A)
![Medchemexpress LLC 4-piperidinamine, N-[(1R,2S)-2-phenylcyclopropyl]-, hydrochloride (1:2), rel- | 2102933-95-7 | 99.5% | 289.24 g/mol | C14H22Cl2N2 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000212683.png-250.jpg)
Medchemexpress LLC 4-piperidinamine, N-[(1R,2S)-2-phenylcyclopropyl]-, hydrochloride (1:2), rel- | 2102933-95-7 | 99.5% | 289.24 g/mol | C14H22Cl2N2 | 1 MG
GSK-LSD1 dihydrochloride is a potent, selective, and irreversible inhibitor of lysine specific demethylase 1 (LSD1) with an IC50 of 16 nM. It is provided for research use in epigenetics and pharmacology studies. Chemical identifiers include CAS 2102933-95-7, formula C14H22Cl2N2, molecular weight 289.24 g/mol, and reported purity ~99.45%.
- Potent, selective, irreversible LSD1 inhibition with low nanomolar potency.
- High chemical purity suitable for research applications.
- Dihydrochloride salt form for improved handling and solubility.
- Well-characterized with supporting certificate of analysis available.
- Intended for epigenetic and pharmacological research use.
Chem-Impex International, Inc. N-Z-1,5-pentanediamine hydrochloride | 18807-74-4 | MFCD00270152 | 5G
N-Z-1,5-pentanediamine hydrochloride, 18807-74-4, MFCD00270152, 5G
eMolecules 6419-36-9 | 3-Pyridylacetic acid hydrochloride | Combi-Blocks | MFCD00012819 | 173.600 | C7H8ClNO2 | 98.000 | Cl.OC(=O)Cc1cccnc1 | 5g | 205392068
3-Pyridylacetic acid hydrochloride | Combi-Blocks | 6419-36-9 | MFCD00012819 | 173.600 | C7H8ClNO2 | 98.000 | Cl.OC(=O)Cc1cccnc1 | 5g | 205392068
Cayman Chemical 1Deoxynojirimycin hydrochlor
An inhibitor of α-glucosidase I and II (IC50s = ~2 µM for both); inhibits virus spread in HIV-infected lymphocyte cultures at 0.4 mM
Chem-Impex International, Inc. Z-1,2-diaminoethane·HCl | 18807-71-1 | MFCD00270150 | 1G
Z-1,2-diaminoethane·HCl, 18807-71-1, MFCD00270150, 1G
Abcam Serotonin hydrochloride (5-HT/5-Hydro x ytryptamine), 5-HT receptor agonist, 1G
MW 212.67 Da, Purity >99%. Endogenous 5-HT receptor agonist. Neurotransmitter involved in diverse physiological functions such as mood, appetite, sleep, sex and temperature in addition to modulating cardiovascular function and the gastrointestinal system. Also a 5-HT transporter substrate.
The product is subject to the following: Abcam Restricted Use Statement
Chem-Impex International, Inc. O-Ethylhydroxylamine hydrochloride | MFCD00012956 | 5G
O-Ethylhydroxylamine hydrochloride, MFCD00012956, 5G
Chem-Impex International, Inc. 2-Iminothiolane hydrochloride | 4781-83-3 | MFCD00039013 | 10G
2-Iminothiolane hydrochloride, 4781-83-3, MFCD00039013, 10G