Hydrochlorides
Medchemexpress LLC DANP dihydrochloride | 761401-89-2 | 99.3% | 25 MG
DANP dihydrochloride is a bulge base recognition probe that strongly and specifically binds to single cytosine and thymine bulges. It can stabilize both single cytosine and thymine bulges in duplex DNA.
- Bulge base recognition probe
- Strongly and specifically binds to single cytosine and thymine bulges
- Stabilizes both single cytosine and thymine bulges in duplex DNA
- Fluorescent dye
Medchemexpress LLC Tirofiban hydrochloride monohydrate | 150915-40-5 | 99.9% | 495.07 | 50 MG
Tirofiban hydrochloride monohydrate is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and possesses antithrombotic activity. It induces proliferation and migration of endothelial cells by stimulating VEGF production, and can significantly reduce myocardial no-reflow and ischemia-reperfusion injury.
- Inhibits fibrinogen binding to platelet integrin receptor (Gp IIb/IIIa).
- Possesses antithrombotic activity.
- Induces proliferation and migration of endothelial cells.
- Reduces myocardial no-reflow and ischemia-reperfusion injury.
- Increases contraction force and improves heart function in rats.
- Demonstrates anticoagulant effect after microvascular anastomosis.
Medchemexpress LLC Mln120b dihydrochloride | 1782573-78-7 | C19H17Cl3N4O2 | 50 MG
MLN120B dihydrochloride is a potent, orally active IKKβ inhibitor (IC50 60 nM) that inhibits multiple myeloma cell growth in vitro and in vivo. It is also used for rheumatoid arthritis research. In vitro, it blocks IκB phosphorylation/degradation and TNF-a-induced p65 NF-κB phosphorylation, reducing proliferation in various multiple myeloma cell lines. In vivo, oral administration reduces tumor growth markers and protects against bone and cartilage destruction in rheumatoid arthritis models.
- Potent, ATP competitive, orally active IKKβ inhibitor.
- Inhibits IκB phosphorylation and degradation.
- Blocks TNF-a-induced p65 NF-κB phosphorylation.
- Reduces proliferation of multiple myeloma cells.
- Inhibits IL-6 secretion from BMSCs.
- Protects against bone and cartilage destruction in rheumatoid arthritis models.
- Prolongs survival in treated animals.
Medchemexpress LLC MRT68921 dihydrochloride | 2080306-21-2 | 99.7% | 507.50 g·mol^-1 | C25H36Cl2N6O | 1 MG
MRT68921 dihydrochloride is a potent dual NUAK1/ULK1 kinase inhibitor used in cancer and autophagy research. It inhibits ULK1 and ULK2 at low nanomolar concentrations, disrupts autophagy, and promotes apoptosis; the compound is supplied as a solid with documented solubility and storage recommendations for research use.
- Inhibits ULK1 and ULK2 at low nanomolar potency.
- Blocks cellular autophagy and promotes apoptosis.
- High reported purity suitable for biochemical assays.
- Soluble in water and DMSO with specified preparation conditions.
- Stable when stored sealed at recommended temperatures.
- Supplied in small solid package sizes for research use.
Medchemexpress LLC Duloxetine hydrochloride | 136434-34-9 | 99.97% | 1 ML
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depressive disorder and generalized anxiety disorder (GAD). This product is for research use only and not sold to patients.
- Serotonin-norepinephrine reuptake inhibitor (SNRI)
- Used for major depressive disorder and generalized anxiety disorder
- For research use only
Medchemexpress LLC HY-107994 500mg Medchemexpress, Aminooxyacetic acid hemihydrochloride CAS:2921-14-4 Purity:>98%
Medchemexpress, HY-107994 500mg Aminooxyacetic acid hemiHCl CAS:2921-14-4 Aminooxyacetic acid hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Amastatin hydrochlor 1mg | 100938-10-1 | 511.01 g/mol | C21H39ClN4O8 | 1 MG
Amastatin hydrochloride is a research-grade, slow, tight-binding competitive inhibitor of aminopeptidases, used in enzymology and biochemical assays to probe aminopeptidase activity. It is supplied as the hydrochloride salt and is provided in small quantities for laboratory research.
- Inhibits multiple aminopeptidases with low-nanomolar Ki values.
- Suitable for enzymology and biochemical research applications.
- Provided as hydrochloride salt for improved handling and solubility.
- High purity (98.0%).
- Molecular weight 511.01 g/mol.
- Available in small pack sizes (1 mg, 5 mg, 10 mg, 50 mg).
Medchemexpress LLC Tirofiban | 144494-65-5 | 440.60 | 5 MG
Tirofiban is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist. It inhibits fibrinogen binding to this receptor, providing antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cells by stimulating VEGF production. It can significantly reduce myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.
- Selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist
- Inhibits fibrinogen binding
- Provides antithrombotic activity
- Induces endothelial cell proliferation and migration
- Stimulates vascular endothelial growth factor (VEGF) production
- Reduces myocardial no-reflow
- Alleviates myocardial microvascular structural and endothelial dysfunction
- Targets integrin
- Affects cytoskeleton pathway
Medchemexpress LLC Piperoxan hydrochloride | 135-87-5 | MFCD00079224 | 99.7% | 269.77 | C14H20ClNO2 | 5 MG
Piperoxan hydrochloride is a small-molecule research reagent described as an α2 adrenoceptor antagonist and a first-generation antihistamine. Supplied as the hydrochloride salt (CAS 135-87-5), it is used in pharmacology and receptor-binding studies to probe adrenergic and histaminergic mechanisms.
- High purity research-grade small molecule (molecular weight 269.77).
- Acts as an α2 adrenoceptor antagonist for receptor pharmacology studies.
- Exhibits first-generation antihistamine properties relevant to histamine assays.
- Available in milligram-scale quantities suitable for in vitro research.
- Provided with SDS and COA documentation for handling and quality assurance.
Medchemexpress LLC 3-Pyridylacetic acid hydrochloride | 6419-36-9 | 173.60 | 1 ML
3-Pyridylacetic acid hydrochloride is a high homolog of nicotinic acid and a decomposition product of nicotine (and other tobacco alkaloids). It can be used to synthesize anti-inflammatory agents or as a precursor for the preparation of herbicides.
- Used to synthesize anti-inflammatory agents
- Precursor for the preparation of herbicides
Medchemexpress LLC Prodipine hydrochloride | 31314-39-3 | 99.8% | 315.9 g/mol | C20H26ClN | 10 MG
Prodipine hydrochloride is a diphenyl-phosphonate derivative used as a research DPP-IV inhibitor. It has been characterized in vitro and in vivo for inhibition of dipeptidyl peptidase IV and is supplied for laboratory research use.
- Inhibits dipeptidyl peptidase IV (DPP-IV) in vitro and in vivo.
- Reported IC50 values: purified rabbit DPP-IV 4.5 μM; rabbit plasma DPP-IV 30 μM.
- High reported purity (99.8%).
- Molecular formula C20H26ClN; molecular weight 315.9 g/mol.
- Intended for biochemical and pharmacological research use only.
- Available in small research pack sizes suitable for assay work.
![Medchemexpress LLC 1-[1-(4-methoxyphenyl)-2-(methylamino)ethyl]cyclohexan-1-ol hydrochloride | 93413-90-2 | 99.6% | 299.83 g/mol | C16H26ClNO2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000263991.png-250.jpg)
Medchemexpress LLC 1-[1-(4-methoxyphenyl)-2-(methylamino)ethyl]cyclohexan-1-ol hydrochloride | 93413-90-2 | 99.6% | 299.83 g/mol | C16H26ClNO2 | 5 MG
High-purity hydrochloride salt of N-desmethyl venlafaxine used as a reference standard for analytical chemistry, impurity profiling, and method development in research laboratories.
- Purity ~99.6%.
- Molecular weight 299.83 g/mol.
- Chemical formula C16H26ClNO2.
- CAS number 93413-90-2.
- Supplied in small-quantity vials suitable for reference standard use.
- Intended for analytical and impurity identification applications.
Medchemexpress LLC VU 0364439 | 1246086-78-1 | C18H13Cl2N3O3S | 1 MG
VU 0364439 is a mGlu4 positive allosteric modulator (PAM) with an EC50 of 19.8 nM. It is for research use only. The compound shows better stability in HLM (63% remaining) than RLM (2% remaining). It is a positive allosteric modulator of human mGlu4 receptor expressed in CHO cells, assessed as potentiation of glutamate-induced calcium mobilization. The appearance is a solid, white to off-white.
- Positive allosteric modulator of human mGlu4 receptor
- EC50 of 19.8 nM
- Better stability in HLM (63% remaining) than RLM (2% remaining)
- Appearance: Solid, white to off-white
- For research use only
Medchemexpress LLC Nylidrin hydrochloride | 849-55-8 | 98.7% | 335.87 g·mol⁻¹ | C19H26ClNO2 | 10 MG
Nylidrin hydrochloride is the hydrochloride salt of buphenine, a research-grade β-adrenergic agonist with reported NMDA NR1A/2B antagonism and antiviral activity against H1N1 influenza. It is used in receptor pharmacology and preclinical models of hemorrhagic shock and allergic responses.
- Orally active β-adrenergic agonist for receptor pharmacology studies.
- Reported NMDA NR1A/2B antagonist activity.
- Demonstrated antiviral activity against multiple H1N1 influenza A subtypes.
- Used in hemorrhagic shock and anti-allergic research models.
- High-purity research reagent suitable for analytical and in vivo studies.
Medchemexpress LLC BAY-6672 hydrochloride | 2247520-31-4 | 98.0% | C26H28BrCl2N3O3 | 25 MG
BAY-6672 hydrochloride is a potent and selective human Prostaglandin F (FP) receptor antagonist with an IC50 value of 11 nM. It is suitable for use as a laboratory chemical for the manufacture of substances.
- Potent and selective human Prostaglandin F (FP) receptor antagonist
- IC50 value of 11 nM
- Stable under recommended storage conditions
- Appears as a white to off-white solid
- Identified for laboratory chemical use