Organic sodium salts
![eMolecules 865-47-4 | Potassium tert-butoxide, Trace metals grade 99.8% | Oakwood Chemical | MFCD00012162 | 112.213 | C4H9KO | 99.000 | [K+].CC(C)(C)[O-] | 25g | 537709487](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000488340.jpg-250.jpg)
eMolecules 865-47-4 | Potassium tert-butoxide, Trace metals grade 99.8% | Oakwood Chemical | MFCD00012162 | 112.213 | C4H9KO | 99.000 | [K+].CC(C)(C)[O-] | 25g | 537709487
Potassium tert-butoxide, Trace metals grade 99.8% | Oakwood Chemical | 865-47-4 | MFCD00012162 | 112.213 | C4H9KO | 99.000 | [K+].CC(C)(C)[O-] | 25g | 537709487
![eMolecules 865-47-4 | Potassium tert-butoxide 20% solution in tetrahydrofuran | Oakwood Chemical | MFCD00012162 | 112.213 | C4H9KO | 0.000 | [K+].CC(C)(C)[O-] | 500g | 537708082](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000488490.jpg-250.jpg)
eMolecules 865-47-4 | Potassium tert-butoxide 20% solution in tetrahydrofuran | Oakwood Chemical | MFCD00012162 | 112.213 | C4H9KO | 0.000 | [K+].CC(C)(C)[O-] | 500g | 537708082
Potassium tert-butoxide 20% solution in tetrahydrofuran | Oakwood Chemical | 865-47-4 | MFCD00012162 | 112.213 | C4H9KO | 0.000 | [K+].CC(C)(C)[O-] | 500g | 537708082
Medchemexpress LLC NBQX disodium | 479347-86-9 | C12H6N4Na2O6S | 1 ML
NBQX disodium is a highly selective and competitive AMPA receptor antagonist, known for its neuroprotective and anticonvulsant activities. It displays high affinity for AMPA and kainate binding sites.
- Highly selective and competitive AMPA receptor antagonist
- Exhibits neuroprotective activity
- Demonstrates anticonvulsant activity
- Targets AMPA receptors
- Decreases seizures induced by PTZ in animal models
- Neuroprotective in focal ischaemia models
![eMolecules 1907-33-1 | Lithium tert-butoxide | Oakwood Chemical | MFCD00050479 | 80.060 | C4H9LiO | 0.000 | [Li+].CC(C)(C)[O-] | 100g | 713093105](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000223612.jpg-250.jpg)
eMolecules 1907-33-1 | Lithium tert-butoxide | Oakwood Chemical | MFCD00050479 | 80.060 | C4H9LiO | 0.000 | [Li+].CC(C)(C)[O-] | 100g | 713093105
Lithium tert-butoxide | Oakwood Chemical | 1907-33-1 | MFCD00050479 | 80.060 | C4H9LiO | 0.000 | [Li+].CC(C)(C)[O-] | 100g | 713093105
Apexbio Technology LLC NBQX 118876-58-7 50mg
NBQX (CAS 118876-58-7) is a potent and selective antagonist of AMPA-type ionotropic glutamate receptors By inhibiting AMPA-mediated excitatory synaptic transmission NBQX disrupts glutamate-induced neuronal signaling thereby attenuating neuronal injury associated with excessive neurotransmitter release This compound has been widely utilized in preclinical studies to investigate neuroprotective and anticonvulsant mechanisms as well as to model and analyze the pathophysiology of neurodegenerative diseases epilepsy and other central nervous system disorders
Apexbio Technology LLC DIBUTYRYL-CAMP SODI. SALT 50MG
DIBUTYRYL-CAMP SODI. SALT 50MG APEXBIO TECHNOLOGIES
Medchemexpress LLC Glycerophosphoric acid (disodium salt hydrate) (α and β mixture) | 98.0% | 500 MG
Glycerophosphoric acid (disodium salt hydrate) (α and β mixture) is a complex that contains both alpha and beta glycerophosphoric acid isomers.
- Is a complex mixture of isomers.
- Suitable for biochemical assay applications.
Medchemexpress LLC CNQX | 115066-14-3 | C9H4N4O4 | 1 ML
CNQX (FG9065) is a potent and competitive AMPA/kainate receptor antagonist with IC50s of 0.3 μM and 1.5 μM, respectively. It is also a competitive non-NMDA receptor antagonist, capable of blocking the expression of fear-potentiated startle in rats. This product is for research use only.
- Potent and competitive AMPA/kainate receptor antagonist
- IC50s of 0.3 μM for AMPA and 1.5 μM for kainate receptors
- Competitive non-NMDA receptor antagonist
- Blocks expression of fear-potentiated startle in rats
- Purity of 99.38%
- Appears as a white to yellow solid
- Soluble in DMSO at 20 mg/mL
Medchemexpress LLC NBQX | 118876-58-7 | C12H8N4O6S | 50 MG
NBQX (FG9202) is a highly selective and competitive antagonist of the AMPA receptor, exhibiting both neuroprotective and anticonvulsant properties.
- Acts as a highly selective and competitive AMPA receptor antagonist.
- Possesses neuroprotective activity.
- Demonstrates anticonvulsant activity.
- Shows high affinity for AMPA and kainate binding sites.
- Exhibits minimal or no affinity for the glutamate recognition site within the NMDA receptor complex.
Medchemexpress LLC DNQX | 2379-57-9 | C8H4N4O6 | 50 MG
DNQX (FG 9041) is a quinoxaline derivative that acts as a selective, potent competitive non-NMDA glutamate receptor antagonist. It exhibits IC50 values of 0.5 μM for AMPA receptors, 2 μM for kainate receptors, and 40 μM for NMDA receptors.
- Selective non-NMDA glutamate receptor antagonist
- Potent competitive antagonist
- IC50s: 0.5 μM (AMPA), 2 μM (kainate), 40 μM (NMDA)
- High purity (99.67%)
- Available as solid and solution
- In vivo dissolution protocols provided
- In vitro, depolarizes thalamic reticular nucleus (TRN) neurons
- In vivo, diminishes phencyclidine (PCP) hsp70 induction
Apexbio Technology LLC CNQX disodium salt 479347-85-8 10mg
CNQX disodium salt (CAS 479347-85-8) is a competitive antagonist of non-NMDA glutamate receptors specifically targeting AMPA and kainate subtypes with IC50 values of 0 3 M and 1 5 M respectively By inhibiting these receptors CNQX blocks fast excitatory synaptic transmission in the central nervous system In thalamic reticular neurons CNQX induces sustained depolarization while showing minimal effect on ventrobasal neurons In vivo administration of CNQX in rats reduces capsaicin-induced c-fos expression in the trigeminal nucleus caudalis without influencing other reticular regions CNQX is widely used to delineate non-NMDA receptor functions in neurophysiological and behavioral studies
Medchemexpress LLC CNQX disodium (FG9065 disodium) | 479347-85-8 | 100.0% | 276.12 g·mol⁻¹ | C9H2N4Na2O4 | 10 MG
CNQX disodium is the disodium salt of 6-cyano-7-nitroquinoxaline-2,3-dione, a potent and competitive AMPA/kainate (non-NMDA) ionotropic glutamate receptor antagonist used as a research reagent in electrophysiology and neuropharmacology. The disodium form is more water-soluble, facilitating preparation of aqueous solutions for in vitro and ex vivo assays.
- Potent AMPA and kainate receptor antagonist with low-micromolar IC50s.
- Water-soluble disodium salt for easy aqueous preparation.
- High purity suitable for research applications.
- Commonly used in electrophysiology and receptor pharmacology studies.
- Supplied in small quantities appropriate for lab-scale experiments.
Apexbio Technology LLC CNQX disodium salt 479347-85-8 50mg
CNQX disodium salt (CAS 479347-85-8) is a competitive antagonist of non-NMDA glutamate receptors specifically targeting AMPA and kainate subtypes with IC50 values of 0 3 M and 1 5 M respectively By inhibiting these receptors CNQX blocks fast excitatory synaptic transmission in the central nervous system In thalamic reticular neurons CNQX induces sustained depolarization while showing minimal effect on ventrobasal neurons In vivo administration of CNQX in rats reduces capsaicin-induced c-fos expression in the trigeminal nucleus caudalis without influencing other reticular regions CNQX is widely used to delineate non-NMDA receptor functions in neurophysiological and behavioral studies
Medchemexpress LLC Benzo[f]quinoxaline-7-sulfonamide, 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo- | 118876-58-7 | C12H8N4O6S | 100 MG
NBQX is a highly selective and competitive AMPA receptor antagonist with demonstrated neuroprotective and anticonvulsant activity.
- Highly selective and competitive AMPA receptor antagonist.
- Exhibits high affinity for AMPA and kainate binding sites.
- Minimal or no affinity for the glutamate recognition site on the NMDA receptor complex.
- Decreases seizures induced by PTZ.
- Neuroprotective in a focal ischaemia model.
Medchemexpress LLC Sodium orthovanadate | 13721-39-6 | 99.4% | 500 MG
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases, and ATPases, acting as a phosphate analogue. It can alter phosphorylation status and inhibit activation pathways during cerebral ischemia. For maximum phosphatase inhibitory activity, it requires a specific activation protocol involving dissolution, pH adjustment, and heating.
- Inhibits protein tyrosine phosphatases, alkaline phosphatases, and ATPases.
- Acts as a phosphate analogue.
- Can alter phosphorylation status of ASK1 and PTEN.
- Inhibits ASK1 activation via PI3-K/Akt.
- Requires specific activation protocol for maximum phosphatase inhibitory activity.