Organic sodium salts
Medchemexpress LLC CNQX disodium | 479347-85-8 | C9H2N4Na2O4 | 5 MG
CNQX disodium (FG9065 disodium) is a potent and competitive AMPA/kainate receptor antagonist. It blocks the expression of fear-potentiated startle in rats and is a competitive non-NMDA receptor antagonist. It is suitable for in vitro and in vivo research.
- Potent and competitive AMPA/kainate receptor antagonist
- Blocks expression of fear-potentiated startle
- Competitive non-NMDA receptor antagonist
- Suitable for neurological disease research
- Inhibitor of ionotropic glutamate receptors
Medchemexpress LLC CNQX disodium | 479347-85-8 | C9H2N4Na2O4 | 25 MG
CNQX disodium is a potent and competitive antagonist for AMPA/kainate receptors, with IC50s of 0.3 μM and 1.5 μM respectively. It also acts as a competitive non-NMDA receptor antagonist and has been shown to block the expression of fear-potentiated startle in rats.
- Potent and competitive AMPA/kainate receptor antagonist
- IC50 values of 0.3 μM for AMPA and 1.5 μM for kainate receptors
- Competitive non-NMDA receptor antagonist
- Demonstrated activity in in vitro studies, including reversible blockade of Schaffer collateral and mossy fibre excitatory postsynaptic potential (EPSP)
- Demonstrated activity in in vivo studies, showing decreased cocaine responses and partial blockade of stepdown inhibitory avoidance
Medchemexpress LLC CNQX disodium | 479347-85-8 | C9H2N4Na2O4 | 50 MG
CNQX disodium (FG9065 disodium) is a potent and competitive antagonist of AMPA/kainate receptors, exhibiting IC50s of 0.3 μM and 1.5 μM respectively. It also functions as a competitive non-NMDA receptor antagonist and has been observed to block the expression of fear-potentiated startle in rats. This compound is primarily utilized in research focused on neurological diseases and iGluR targets.
- Potent and competitive AMPA/kainate receptor antagonist
- Competitive non-NMDA receptor antagonist
- Blocks expression of fear-potentiated startle in rats
- Used in neurological disease research
- Targets iGluR
Medchemexpress LLC CNQX disodium | 479347-85-8 | C9H2N4Na2O4 | 100 MG
CNQX disodium is a potent and competitive AMPA/kainate receptor antagonist. It acts as a competitive non-NMDA receptor antagonist and has demonstrated effectiveness in blocking the expression of fear-potentiated startle in rats.
- Potent and competitive AMPA/kainate receptor antagonist.
- Competitive non-NMDA receptor antagonist.
- Blocks the expression of fear-potentiated startle in rats.
- Reversibly blocks Schaffer collateral and mossy fibre excitatory postsynaptic potential (EPSP) in hippocampal slices.
- Produces a selective and dose-dependent reduction in the amplitude of the monosynaptic component of the DR-VRR.
Apexbio Technology LLC CNQX disodium salt 479347-85-8 10mg
CNQX disodium salt (CAS 479347-85-8) is a competitive antagonist of non-NMDA glutamate receptors specifically targeting AMPA and kainate subtypes with IC50 values of 0 3 M and 1 5 M respectively By inhibiting these receptors CNQX blocks fast excitatory synaptic transmission in the central nervous system In thalamic reticular neurons CNQX induces sustained depolarization while showing minimal effect on ventrobasal neurons In vivo administration of CNQX in rats reduces capsaicin-induced c-fos expression in the trigeminal nucleus caudalis without influencing other reticular regions CNQX is widely used to delineate non-NMDA receptor functions in neurophysiological and behavioral studies
Apexbio Technology LLC CNQX disodium salt 479347-85-8 50mg
CNQX disodium salt (CAS 479347-85-8) is a competitive antagonist of non-NMDA glutamate receptors specifically targeting AMPA and kainate subtypes with IC50 values of 0 3 M and 1 5 M respectively By inhibiting these receptors CNQX blocks fast excitatory synaptic transmission in the central nervous system In thalamic reticular neurons CNQX induces sustained depolarization while showing minimal effect on ventrobasal neurons In vivo administration of CNQX in rats reduces capsaicin-induced c-fos expression in the trigeminal nucleus caudalis without influencing other reticular regions CNQX is widely used to delineate non-NMDA receptor functions in neurophysiological and behavioral studies
Medchemexpress LLC CNQX disodium (FG9065 disodium) | 479347-85-8 | 100.0% | 276.12 g·mol⁻¹ | C9H2N4Na2O4 | 10 MG
CNQX disodium is the disodium salt of 6-cyano-7-nitroquinoxaline-2,3-dione, a potent and competitive AMPA/kainate (non-NMDA) ionotropic glutamate receptor antagonist used as a research reagent in electrophysiology and neuropharmacology. The disodium form is more water-soluble, facilitating preparation of aqueous solutions for in vitro and ex vivo assays.
- Potent AMPA and kainate receptor antagonist with low-micromolar IC50s.
- Water-soluble disodium salt for easy aqueous preparation.
- High purity suitable for research applications.
- Commonly used in electrophysiology and receptor pharmacology studies.
- Supplied in small quantities appropriate for lab-scale experiments.
![eMolecules Medchem Express / CNQX (disodium) / 5mg / 761738560 / HY-15066A / / 479347-85-8 / [null] / 276.119 / C9H2N4Na2O4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502482018.JPG-250.jpg)
eMolecules Medchem Express / CNQX (disodium) / 5mg / 761738560 / HY-15066A / / 479347-85-8 / [null] / 276.119 / C9H2N4Na2O4
Medchem Express / CNQX (disodium) / 5mg / 761738560 / HY-15066A / / 479347-85-8 / [null] / 276.119 / C9H2N4Na2O4