Organofluorides

TARGETMOL CHEMICALS INC ML-335 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ML-335 is a u-(delta) isomer-targeted agonist a uOR-(delta)OR-biased ligand that can serve as a scaffold for the development of unique types of (isomer-biased) drugs.ML-335 is a MOR (u-opioid receptor)/DOR ((delta)-opioid receptor) heterodimer with anti-injury sensory activity and pain inhibitory activity. purity: 98%

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Medchemexpress LLC GUCY2C/Guanylyl cycl 10ug

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Recombinant rat Guanylyl Cyclase C (GUCY2C) produced in HEK293 cells with N-terminal His and C-terminal Myc tags. Supplied in small pack sizes (10 μg available) for use in biochemical and cell-based assays to study receptor activation, cGMP production, and toxin-receptor interactions. For research use only.

• Expressed in HEK293 cells for mammalian-like post-translational modifications.
• Includes N-terminal His tag and C-terminal Myc tag for purification and detection.
• Suitable for studies of receptor activation and cGMP signaling.
• Available in small 10 μg pack sizes for assay development.
• Provided for research use only; not for human or diagnostic use.

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eMolecules​ 344591-91-9 | (1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)boronic acid | ChemScene | MFCD08701785 | 193.920 | C5H6BF3N2O2 | 97.000 | Cn1nc(cc1B(O)O)C(F)(F)F | 1g | 572233746

(1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)boronic acid | ChemScene | 344591-91-9 | MFCD08701785 | 193.920 | C5H6BF3N2O2 | 97.000 | Cn1nc(cc1B(O)O)C(F)(F)F | 1g | 572233746

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Medchemexpress LLC Cyclo(CLLFVY) | 1446322-73-1 | 99.37% | 738.94 | 10 MG

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cyclo(CLLFVY) is an inhibitor for hypoxia inducible factor-1 (HIF-1), with IC50 values of 19 μM (in U2OS) and 16 μM (in MCF-7). It binds to the PAS-B domain of HIF-1α, thereby inhibiting HIF-1 dimerization and transcriptional activity. This compound also downregulates the expression of hypoxia response genes, such as VEGF and CAIX, demonstrating antitumor properties against HIF-1 associated cancers.

• Inhibitor for hypoxia inducible factor-1 (HIF-1)
• Binds to the PAS-B domain of HIF-1α
• Inhibits HIF-1 dimerization and transcriptional activity
• Downregulates the expression of hypoxia response genes (e.g., VEGF and CAIX)
• Exhibits antitumor activity against HIF-1 associated cancers

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Medchemexpress LLC Dl-α-(difluoromethyl)arginine | 69955-43-7 | MFCD18252556 | 95.0% | 224.21 | C7H14F2N4O2 | 5 MG

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DL-α-(Difluoromethyl)arginine is a small-molecule, enzyme-activated, irreversible inhibitor of arginine decarboxylases used for biochemical and microbiological research. It has documented activity blocking arginine decarboxylase in organisms such as E. coli and Pseudomonas aeruginosa and is supplied as a solid suitable for in vitro studies.

• Irreversible arginine decarboxylase inhibition suitable for mechanistic studies.
• Documented activity in bacterial systems such as E. coli and Pseudomonas aeruginosa.
• Solid, white to off-white appearance simplifies handling and weighing.
• Solubility: insoluble or slightly soluble in DMSO (< 1 mg/mL); plan appropriate solvents.
• Purity approximately 95.0% as supplied.
• Store sealed, away from moisture at -20°C; in solution store at -80°C for long-term stability.

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Medchemexpress LLC Cyclo(phe-phe) | 2862-51-3 | MFCD00190985 | 98.8% | 294.35 g/mol | C18H18N2O2 | 50 MG

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Cyclo(Phe-Phe) is a cyclic dipeptide (cyclo-phenylalanyl-phenylalanine) used as a research reagent in peptide screening and biochemical assays. It is supplied as a white to off-white solid with high purity; handle according to the safety data sheet guidance.

• High purity: 98.8%.
• Molecular weight: 294.35 g/mol.
• Chemical formula: C18H18N2O2.
• Physical state: Solid, white to off-white.
• Recommended storage: Powder at -80°C (up to 2 years) or -20°C (up to 1 year), sealed.
• Documentation: Datasheet, certificate of analysis, and SDS available.

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eMolecules​ 2639960-45-3 | (3S)-3-(2,2,2-trifluoroethyl)pyrrolidine;hydrochloride | 1g

Ambeed | Isopropyldiphenylphosphine | 250mg | 534580692 | A343809 | 6372-40-3 | MFCD00015028 | 228.275 | C15H17P

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Medchemexpress LLC Potassium 2-((6-chloro-dodecafluorohexyl)oxy)-tetrafluoroethane-1-sulfonate | 73606-19-6 | MFCD11975311 | 98.0% | 570.67 g/mol | C8ClF16KO4S | 25 MG

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6:2 Cl-PFAES (potassium salt) is a chlorinated perfluoroalkyl ethane sulfonate supplied for laboratory research. It is used in environmental, toxicological, and analytical studies of fluorinated surfactants and as a reference standard. The compound is a high-purity material provided in small quantities; consult the safety data sheet before handling due to specific hazard information.

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eMolecules​ 2416056-30-7 | Potassium (2,2-difluorocyclopropyl)trifluoroborate | ChemScene183.960 | C3H3BF5K | 97.000 | [K+].F[B-](F)(F)C1CC1(F)F | 250mg | 714105099

Potassium (2,2-difluorocyclopropyl)trifluoroborate | ChemScene | 2416056-30-7183.960 | C3H3BF5K | 97.000 | [K+].F[B-](F)(F)C1CC1(F)F | 250mg | 714105099

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eMolecules​ 248274-16-0 | 1-(5-Trifluoromethyl-pyridin-2-yl)-ethanone | J & W PharmLab, LLC | MFCD10696269 | 189.137 | C8H6F3NO | 96.000 | CC(=O)c1ccc(cn1)C(F)(F)F | 5g | 249991410

1-(5-Trifluoromethyl-pyridin-2-yl)-ethanone | J & W PharmLab, LLC | 248274-16-0 | MFCD10696269 | 189.137 | C8H6F3NO | 96.000 | CC(=O)c1ccc(cn1)C(F)(F)F | 5g | 249991410

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eMolecules​ 6674-22-2 | 1,8-Diazabicyclo[5.4.0]undec-7-ene | Synthonix | MFCD00006930 | 152.241 | C9H16N2 | 95.000 | C1CN=C2CCCCCN2C1 | 5g | 767156199

1,8-Diazabicyclo[5.4.0]undec-7-ene | Synthonix | 6674-22-2 | MFCD00006930 | 152.241 | C9H16N2 | 95.000 | C1CN=C2CCCCCN2C1 | 5g | 767156199

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Medchemexpress LLC Trans-1,2-cyclohexanediaminetetraacetic acid | 13291-61-7 | 97.0% | C14H22N2O8 | 1 ML

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trans-1,2-Cyclohexanediaminetetraacetic acid is a commonly used aminopolycarboxylic acid and a strong chelator of heavy metal ions.

• Strong chelator of heavy metal ions
• Available as a solid or in solution (10 mM in DMSO)

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eMolecules​ 5222-73-1 | dimethoxycyclobut-3-ene-1,2-dione | Pharmablock | MFCD00101316 | 142.110 | C6H6O4 | 97.000 | COc1c(OC)c(=O)c1=O | 1g | 784549583

dimethoxycyclobut-3-ene-1,2-dione | Pharmablock | 5222-73-1 | MFCD00101316 | 142.110 | C6H6O4 | 97.000 | COc1c(OC)c(=O)c1=O | 1g | 784549583

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eMolecules​ 420-37-1 | Trimethyloxonium tetrafluoroborate | Oakwood Chemicals | MFCD00011798 | 147.910 | C3H9BF4O | 95.000 | C[O+](C)C.F[B-](F)(F)F | 5g | 480134986

Trimethyloxonium tetrafluoroborate | Oakwood Chemicals | 420-37-1 | MFCD00011798 | 147.910 | C3H9BF4O | 95.000 | C[O+](C)C.F[B-](F)(F)F | 5g | 480134986

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eMolecules​ 5470-96-2 | Quinoline-2-carboxaldehyde | ChemScene | MFCD00075032 | 157.172 | C10H7NO | 98.000 | O=Cc1ccc2ccccc2n1 | 25g | 536852228

Quinoline-2-carboxaldehyde | ChemScene | 5470-96-2 | MFCD00075032 | 157.172 | C10H7NO | 98.000 | O=Cc1ccc2ccccc2n1 | 25g | 536852228

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