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Organofluorides

Organic compounds that contain one or more fluorine atoms.

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1

Medchemexpress LLC KJ Pyr 9 | 581073-80-5 | 99.6% | 385.37 | 50 MG
SDP

KJ Pyr 9 is an inhibitor of MYC with a Kd of 6.5 nM in in vitro assay. It interferes with MYC-MAX complex formation in cells and specifically inhibits MYC-induced oncogenic transformation in cell culture. It also preferentially interferes with the proliferation of MYC-overexpressing human and avian cells.

  • Inhibits MYC-MAX complex formation
  • Inhibits MYC-induced oncogenic transformation
  • Reduces MYC-driven transcriptional signature
  • Inhibits proliferation of NCI-H460, MDA-MB-231, and SUM-159PT cell lines
  • Halts tumor growth in vivo

ENCOMPASS_PREFERRED
2

Medchemexpress LLC KJ Pyr 9 | 581073-80-5 | 99.6% | 385.37 | 5 MG
SDP

KJ Pyr 9 is an inhibitor of MYC, interfering with MYC-MAX complex formation and inhibiting oncogenic transformation. It reduces the MYC-driven transcriptional signature and inhibits the proliferation of various cell lines, with higher sensitivity for Burkitt lymphoma cell lines. In vivo, it demonstrates the ability to halt tumor growth.

  • Interferes with MYC-MAX complex formation
  • Inhibits MYC-induced oncogenic transformation in cell culture
  • Reduces the MYC-driven transcriptional signature
  • Inhibits proliferation of NCI-H460, MDA-MB-231, and SUM-159PT cell lines
  • More sensitive for Burkitt lymphoma cell lines with high c-MYC expression
  • Halts tumor growth in vivo at 10 mg/kg

ENCOMPASS_PREFERRED
3

Medchemexpress LLC 9-Bromonon-1-ene | 89359-54-6 | 205.14 | 50 G
SDP

9-Bromonon-1-ene is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is sold for research purposes only and not for patient use.

  • Biochemical reagent for life science research.
  • Pure form storage: -20°C for 3 years, 4°C for 2 years.
  • In solvent storage: -80°C for 6 months, -20°C for 1 month.

ENCOMPASS_PREFERRED
4

Medchemexpress LLC 8-Quinolinecarboxylic acid | 86-59-9 | 173.17 | 1 ML
SDP

Quinoline-8-carboxylic acid is a herbicide supplied as a 10 mM solution in 1 mL of DMSO. This chemical compound has a molecular weight of 173.17 and a purity exceeding 99.7%. It is intended for research use only.

  • Supplied as a 10 mM solution in 1 mL DMSO
  • Purity >99.7%
  • Molecular weight: 173.17
  • CAS number: 86-59-9
  • Functions as a herbicide
  • Solution storage at -80°C for 6 months or -20°C for 1 month

ENCOMPASS_PREFERRED
5

Medchemexpress LLC 4-[4-[(2-thiiranylmethyl)sulfonyl]phenoxy]-benzenemethanamine monohydrochloride | 1807453-83-3 | MFCD34469331 | 97.2% | 371.90 | C16H18ClNO3S2 | 1MG
SDP

ND-336 is a small-molecule selective inhibitor of matrix metalloproteinases MMP-2, MMP-9, and MMP-14 used in biochemical and in vivo research; it exhibits low-nanomolar to sub-micromolar potency and has been reported to accelerate diabetic wound healing in mice by reducing inflammation and promoting angiogenesis and re-epithelialization. The compound is supplied as a white to off-white solid, with high purity and recommended cold storage for long-term stability.

  • Selective inhibitor of MMP-2, MMP-9, and MMP-14.
  • Potency: Ki = 85 nM (MMP-2), 150 nM (MMP-9), 120 nM (MMP-14).
  • Shown to accelerate wound healing in diabetic mouse models.
  • High purity (97.2%) and white to off-white solid appearance.
  • Soluble in DMSO at 30 mg/mL (requires ultrasonic and warming).
  • Storage: solid at -20°C; in solvent -80°C for 6 months, -20°C for 1 month.
  • Suitable for biochemical assays and topical in vivo studies.

ENCOMPASS_PREFERRED
6

Medchemexpress LLC Nd-336 | 1807453-83-3 | MFCD34469331 | 97.2% | 371.90 g·mol⁻¹ | C16H18ClNO3S2 | 500UG
SDP

ND-336 is a small-molecule matrix metalloproteinase (MMP) inhibitor (CAS 1807453-83-3) used for preclinical research. It selectively inhibits MMP-2, MMP-9, and MMP-14 and has been reported to accelerate diabetic wound healing in animal models. The compound has molecular formula C16H18ClNO3S2, molecular weight ~371.90 g·mol⁻¹, and listed purity around 97.2%.

  • Selective inhibitor of MMP-2, MMP-9, and MMP-14.
  • Reported to accelerate diabetic wound healing in vivo.
  • Molecular formula C16H18ClNO3S2 and molecular weight ~371.90 g·mol⁻¹.
  • High listed purity of approximately 97.2% suitable for research use.
  • Long-term storage recommended at -20°C; in solution store at -80°C for extended stability.
  • Intended for in vitro and in vivo research applications; not for human use.

ENCOMPASS_PREFERRED