Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Tri(Amino-PEG3-amide)-amine | 2523025-40-1 | MFCD28142446 | 98.0% | C33H69N7O12 | 25 MG
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Tri(Amino-PEG3-amide)-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Apexbio Technology LLC OSI-930 728033-96-3 5mg
OSI-930 (CAS 728033-96-3) is a small molecule inhibitor targeting multiple receptor tyrosine kinases including Flt1 (IC 8 nM) KDR/VEGFR2 (IC 9 nM) CSF-1R (IC 15 nM) Lck c-Raf and Kit (IC 80 nM) In cellular studies OSI-930 inhibits proliferation and induces apoptosis in HMC-1 cells whose survival is dependent on Kit signaling while exhibiting minimal effects on COLO-205 cells under standard conditions Additionally OSI-930 inactivates cytochrome P450 3A4 in a time- and concentration-dependent manner and alters its spectral properties These characteristics make OSI-930 a valuable tool compound for investigating receptor tyrosine kinase signaling pathways and related cellular processes in cancer research
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Medchemexpress LLC GSK2807 trifluoroacetate | 2245255-66-5 | 99.8% | 566.53 g/mol | C21H33F3N8O7 | 50 MG
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GSK2807 trifluoroacetate is a selective, SAM-competitive inhibitor of the protein methyltransferase SMYD3 with potent biochemical activity (Ki = 14 nM; IC50 = 130 nM). Supplied as the trifluoroacetate salt and formulated for research applications, it is intended for biochemical and cellular studies of SMYD3-mediated methylation and epigenetic regulation.
- Provided as a trifluoroacetate salt for improved handling
- Potent SMYD3 inhibition (Ki 14 nM; IC50 130 nM)
- High purity suitable for research use
- Compact 50 mg package size for assay development
- Well characterized for biochemical and cellular studies
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CAMPBELL SCIENCE BSTFA + 1% TMCS | 25561-30-2 | MFCD00008269 | 100 g
BSTFA + 1% TMCS | Purity: 98% | Mol Wt: 257.40 | 25561-30-2 | MFCD00008269 | 100 g
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Medchemexpress LLC Tri(Amino-PEG5-amide)-amine | 2055013-52-8 | 99.9% | C45H93N7O18 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Tri(Amino-PEG5-amide)-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other to the target protein. This mechanism allows PROTACs to effectively degrade specific proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Chlorotriethylsilane | 994-30-9 | MFCD00000507 | ≥97.0% | 150.72 g/mol | C6H15ClSi | 25 G
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Chlorotriethylsilane (triethylsilyl chloride) is an organosilicon reagent used in organic synthesis, commonly employed as a silylating agent and protecting group. It is supplied as a colorless to light yellow liquid with documented purity and storage recommendations for research use.
- Used as a silylating reagent and protecting group in organic synthesis.
- Supplied as a colorless to light yellow liquid; available in 25 g and larger sizes.
- Molecular formula C6H15ClSi; CAS number 994-30-9.
- Purity ≥97.0% (NMR) as verified by certificate of analysis.
- Intended for research use only; not for clinical, diagnostic, or food use.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC NH-bis(C2-PEG2-NH-Boc) | 2182601-69-8 | 250 MG
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NH-bis(C2-PEG2-NH-Boc) | 2182601-69-8 | 250 MG
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Apexbio Technology LLC Endothelin-1 (1-15), amide, human 1mg
Endothelin-1 1-15 amide human is a peptide fragment derived from the N-terminus of Endothelin-1 which targets endothelin receptor subtypes ETA and ETB It is designed to modulate vascular tone through activation of G protein-coupled receptor signaling thereby influencing blood pressure regulation and vascular function Endothelin-1 1-15 amide human exerts its biological activity primarily through receptor activation and signal transduction mechanisms involving endothelin receptors Based on these pharmacological properties Endothelin-1 1-15 amide human holds research potential in the investigation of receptor-ligand interactions receptor selectivity and the pathophysiology of hypertension cancer diabetes pain modulation and cerebral vasospasm
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Apexbio Technology LLC OSI-420 free base 183321-86-0 5mg
OSI-420 free base (CAS 183321-86-0) is an active metabolite of erlotinib (OSI-774) exhibiting inhibitory activity against epidermal growth factor receptor (EGFR) tyrosine kinase Mechanistically OSI-420 inhibits EGFR by binding competitively to the ATP-binding site within the intracellular kinase domain thus preventing receptor autophosphorylation and subsequent signaling Additionally through EGFR inhibition it can trigger apoptosis via mitochondrial disruption including loss of mitochondrial membrane potential and cytochrome c release OSI-420 is utilized in biomedical research for studying EGFR-related signaling pathways and apoptosis mechanisms
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Medchemexpress LLC LL-37 amide | 597562-32-8 | 99.9% | 4492.28 | 5 MG
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LL-37 amide is a selective agonist of formyl peptide receptor-like FPRL1. It effectively inhibits periodontal pathogens by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. This compound also regulates inflammatory responses and promotes angiogenesis. The amidation modification reduces its sensitivity to serum inhibition and improves its stability. It is primarily used in research on infection-related diseases and wound healing due to its key activities in bactericidal action, immunomodulation, and wound healing.
- Selective FPRL1 agonist
- Effectively inhibits periodontal pathogens
- Disrupts bacterial cell membranes
- Regulates inflammation and promotes angiogenesis
- Amidation enhances stability and reduces serum inhibition
- Used in research for infection and wound healing
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Apexbio Technology LLC Epidermal growth factor receptor (994-1002) acetyl/amide 5mg
Epidermal growth factor receptor 994-1002 acetyl amide is a peptide fragment derived from the epidermal growth factor receptor (EGFR) acetylated and amidated at its termini It is designed to serve as a tool for investigating receptor-ligand interactions and receptor activation mechanisms associated with EGFR-mediated signaling pathways Epidermal growth factor receptor 994-1002 acetyl amide acts by enabling the study of EGFR activation particularly receptor dimerization and autophosphorylation processes Based on its biological characteristics this peptide has research potential in evaluating therapeutic strategies targeting EGFR-mediated oncogenesis including studies of proliferation differentiation migration and survival in malignancies such as glioblastoma and lung cancers
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![eMolecules 58201-66-4 | (Bromodifluoromethyl)triphenylphosphonium bromide | Combi-Blocks | MFCD00191843 | 472.108 | C19H15Br2F2P | 95.000 | [Br-].FC(F)(Br)[P+](c1ccccc1)(c1ccccc1)c1ccccc1 | 1g | 495746774](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502185039.JPG-250.jpg)
eMolecules 58201-66-4 | (Bromodifluoromethyl)triphenylphosphonium bromide | Combi-Blocks | MFCD00191843 | 472.108 | C19H15Br2F2P | 95.000 | [Br-].FC(F)(Br)[P+](c1ccccc1)(c1ccccc1)c1ccccc1 | 1g | 495746774
(Bromodifluoromethyl)triphenylphosphonium bromide | Combi-Blocks | 58201-66-4 | MFCD00191843 | 472.108 | C19H15Br2F2P | 95.000 | [Br-].FC(F)(Br)[P+](c1ccccc1)(c1ccccc1)c1ccccc1 | 1g | 495746774
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 3-METHYL-2-CYCLOPENT 25G | 25G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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3-METHYL-2-CYCLOPENT 25G | 25G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 65094-22-6 | Bromodifluoromethyl diethylphosphonate | Oakwood Chemical | MFCD00069118 | 267.007 | C5H10BrF2O3P | 97.000 | CCOP(=O)(OCC)C(F)(F)Br | 100g | 537671593
Bromodifluoromethyl diethylphosphonate | Oakwood Chemical | 65094-22-6 | MFCD00069118 | 267.007 | C5H10BrF2O3P | 97.000 | CCOP(=O)(OCC)C(F)(F)Br | 100g | 537671593
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![Medchemexpress LLC 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol | 1374639-77-6 | 99.0% | 251.72 | 100 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000404382-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol | 1374639-77-6 | 99.0% | 251.72 | 100 G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
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2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol is a drug intermediate used in the synthesis of various active compounds. This product is intended for research purposes only and is not suitable for patient use.
- Drug intermediate for synthesis of various active compounds.
- Intended for research use only.
- Available in multiple quantities.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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