Organo-Metalloid Compounds
- (1)
- (19)
- (139)
- (2)
- (10)
- (1)
- (1)
- (27)
- (20)
- (4)
- (62)
- (96)
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- (1)
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- (206)
- (153)
- (1)
- (25)
- (23)
- (11)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (251)
- (85)
- (1)
- (1)
- (20)
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- (9)
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- (54)
- (3)
- (10)
- (1)
- (8)
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- (8)
- (4)
- (2)
- (21)
- (2)
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- (5)
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- (1)
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- (1)
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- (5)
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- (1)
- (1)
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- (2)
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- (18)
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- (2)
- (2)
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- (4)
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- (2)
- (1)
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- (1)
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- (3)
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- (1)
- (1)
- (7)
- (3)
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- (9)
- (1)
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- (4)
- (1)
- (7)
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- (1)
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- (1)
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- (1)
- (10)
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- (2)
- (2)
- (4)
- (7)
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- (2)
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- (5)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (5)
- (9)
- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (2)
- (2)
- (1)
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- (6)
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- (1)
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- (10)
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- (1)
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- (1)
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- (1)
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- (1)
- (8)
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- (1)
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- (1)
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- (8)
- (6)
- (1)
- (3)
- (9)
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- (1)
- (3)
- (1)
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- (1)
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- (1)
- (10)
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- (1)
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- (15)
- (1)
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Filtered Search Results
Aobchem AOBCHEM
5001059969 TETRAETHYL DIMETHYLAMINO MET
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Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 TFA (cereblon ligand-linker conjugates 5 TFA) | 2414913-97-4 | 99.0% | 500 MG
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Pomalidomide-PEG3-C2-NH2 TFA is a synthetic E3 ligase ligand-linker conjugate. It is composed of a pomalidomide-based cereblon ligand and a 3-unit PEG linker.
- Comprises a pomalidomide-based cereblon ligand.
- Includes a 3-unit PEG linker.
- Can be used for the synthesis of PROTACs.
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eMolecules 2247367-07-1 | 4,4,5,5-tetraethyl-2-(4,4,5,5-tetraethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane | Pharmablock366.160 | C20H40B2O4 | 97.000 | CCC1(CC)OB(OC1(CC)CC)B1OC(CC)(CC)C(CC)(CC)O1 | 5g | 783662447
4,4,5,5-tetraethyl-2-(4,4,5,5-tetraethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane | Pharmablock | 2247367-07-1366.160 | C20H40B2O4 | 97.000 | CCC1(CC)OB(OC1(CC)CC)B1OC(CC)(CC)C(CC)(CC)O1 | 5g | 783662447
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eMolecules 2247367-07-1 | 4,4,5,5-tetraethyl-2-(4,4,5,5-tetraethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane | Pharmablock366.160 | C20H40B2O4 | 97.000 | CCC1(CC)OB(OC1(CC)CC)B1OC(CC)(CC)C(CC)(CC)O1 | 25g | 783664274
4,4,5,5-tetraethyl-2-(4,4,5,5-tetraethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane | Pharmablock | 2247367-07-1366.160 | C20H40B2O4 | 97.000 | CCC1(CC)OB(OC1(CC)CC)B1OC(CC)(CC)C(CC)(CC)O1 | 25g | 783664274
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Medchemexpress LLC Azido-PEG5-acid | 1425973-16-5 | >98.0% | 335.35 g/mol | C13H25N3O7 | 250 MG
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Azido-PEG5-acid is an azide-functional, five-unit polyethylene glycol (PEG5) linker used for conjugation chemistry, including PROTAC and antibody-drug conjugate synthesis, and for click-chemistry applications. Supplied for research use only.
- Peg5 linker with azide functionality for click chemistry.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Compatible with strain-promoted azide-alkyne cycloaddition (SPAAC) using DBCO or BCN reagents.
- Purity ≥98.0%.
- Appearance: colorless to light yellow liquid.
- Storage: pure form stable at -20°C for 3 years and 4°C for 2 years.
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Medchemexpress LLC 2-(2-(2-Bromoethoxy)ethoxy)ethyl methanesulfonate | 2702323-73-5 | 95.0% | 291.16 | 25 MG
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Br-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Protacs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase.
- The other ligand is for the target protein.
- Protacs exploit the intracellular ubiquitin-proteasome system.
- Selectively degrade target proteins.
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Medchemexpress LLC 1,11-Bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 50 MG
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BM-PEG3 is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). PROTACs are molecules that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This compound has a molecular weight of 352.34 and a chemical formula of C16H20N2O7, appearing as a white to light yellow solid. It is soluble in DMSO, with recommendations for proper storage and handling for both powder and solvent forms.
- It is a polyethylene glycol-based linker.
- It is used in the synthesis of proteolysis-targeting chimeras.
- It aids in the degradation of target proteins.
- It has a high purity of 98.0%.
- It is available as a white to light yellow solid.
- It can be dissolved in DMSO for in vitro experiments.
- It can be formulated for in vivo studies using specific co-solvents like DMSO and corn oil.
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Medchemexpress LLC N-Boc-C1-PEG3-C3-NH2 | 194920-62-2 | 320.42 | 5 G
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N-Boc-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is for research use only.
- This product is a PEG-based PROTAC linker.
- PROTACs are composed of two different ligands linked together; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein.
- PROTACs function by utilizing the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
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Medchemexpress LLC TFP-PEG3-TFP 50mg
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TFP-PEG3-TFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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eMolecules 867062-95-1 | Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 25g | 596090330
Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | 867062-95-1 | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 25g | 596090330
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Medchemexpress LLC Folate-PEG3-C2-acid | 97.6% | 644.63 g/mol | C28H36N8O10 | 10 MG
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Folate-PEG3-C2-acid is the acid fragment of a folate-PEG3-based NHS ester and serves as a PEG-type PROTAC linker building block used in the synthesis of PROTAC molecules and folate-conjugated ligands for receptor-targeting studies.
- Purity: 97.6%.
- Molecular weight: 644.63 g/mol.
- Solubility: soluble in DMSO at 33.33 mg/mL (51.70 mM); ultrasonication and heating may aid dissolution.
- Storage: store at 4°C protected from light; in solvent keep at -80°C (6 months) or -20°C (1 month), protected from light.
- Physical state: light yellow to yellow solid.
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Medchemexpress LLC BIOTIN-PEG3-IODOACET | 5MG
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BIOTIN-PEG3-IODOACET | 5MG
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Medchemexpress LLC 5,8,11-Trioxa-2-azatetradecanedioic acid, 1-(4-cycloocten-1-yl) ester | 2141981-86-2 | MFCD31811538 | 96.0% | 373.44 | 25 MG
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TCO-PEG3-acid is a click chemistry reagent that contains a TCO group, which can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. It is also a click chemistry PEG linker with a terminal carboxylic acid group. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators to form a stable amide bond.
- Contains a TCO group for inverse electron demand Diels-Alder reaction (iEDDA)
- Reacts with molecules containing Tetrazine groups
- Functions as a click chemistry PEG linker
- Terminal carboxylic acid group
- Forms stable amide bonds with primary amine groups in the presence of activators
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Medchemexpress LLC VH032-PEG5-C6-Cl (HaloPROTAC 2) | 1799506-06-1 | 99.9% | 783.41 | 100 MG
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VH032-PEG5-C6-Cl (HaloPROTAC 2) is a conjugate that combines ligands for E3 ligase with a 21-atom-length linker. The linker's connector features a Halogen group, and the compound integrates a VH032-based VHL ligand with a 5-unit PEG linker. This product is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. It is intended for research use only and is not sold to patients.
- Conjugate of ligands for E3 and a 21-atom-length linker.
- Connector of the linker is a Halogen group.
- Incorporates a VH032 based VHL ligand and a 5-unit PEG linker.
- Capable of inducing the degradation of GFP-HaloTag7 in cell-based assays.
- Treatment for 24 hours leads to nearly 70% degradation of GFP-Halotag7 at 2.5 μM.
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Medchemexpress LLC Fmoc-NH-PEG3-CH2CH2COOH | 867062-95-1 | 99.8% | 443.49 g/mol | C24H29NO7 | 10 G
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Fmoc-NH-PEG3-CH2CH2COOH is an Fmoc-protected, PEG3-based linker used as a cleavable ADC linker and as a PEG-based PROTAC linker in synthetic and bioconjugation applications.
- Fmoc-protected amino-PEG3 linker suitable for conjugation.
- Used in ADC and PROTAC synthesis applications.
- Molecular formula C24H29NO7 and molecular weight 443.49 g/mol.
- High purity (99.8%) appropriate for research use.
- Available in multiple pack sizes including 10 G.
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