Organo-Metalloid Compounds
![Medchemexpress LLC Ethanol, 2-[2-(2-aminoethoxy)ethoxy]- | 6338-55-2 | 149.19 | 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000446591.png-250.jpg)
Medchemexpress LLC Ethanol, 2-[2-(2-aminoethoxy)ethoxy]- | 6338-55-2 | 149.19 | 10 G
NH2-PEG3, also known as PROTAC Linker 35, is a polyethylene glycol (PEG) linker used in the synthesis of PROTACs, including PROTAC (β-NF-JQ1). PROTACs are compounds designed to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Polyethylene glycol (PEG) linker
- Used in the synthesis of PROTACs
- Facilitates the synthesis of PROTAC (β-NF-JQ1)
- Enables targeted protein degradation via the ubiquitin-proteasome system
Medchemexpress LLC 2',3'-O-Isopropylideneadenosine | 362-75-4 | 307.31 | 10 MM 1 ML
2',3'-O-Isopropylideneadenosine is an adenosine analog primarily functioning as a smooth muscle vasodilator. It has also been observed to hinder cancer progression. Intended for research use only.
- Acts as a smooth muscle vasodilator
- Inhibits cancer progression
- White to off-white solid appearance
- Purity of 99.97%
Medchemexpress LLC Bis(1-chloro-2-propyl) phosphate (BCIPP) | 789440-10-4 | C6H13Cl2O4P | 1 MG
Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone.
- Holds potential for research on metabolism-related diseases caused by environmental exposure.
Medchemexpress LLC (E)-Cyclooct-2-en-1-yl (2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)carbamate | 98.4% | 344.45 | C17H32N2O5 | 10 MG
TCO-PEG3-NH2 is a click-chemistry reagent composed of a trans-cyclooctene (TCO) group linked to a three-unit polyethylene glycol spacer terminating in a primary amine. It enables fast bioorthogonal inverse-electron-demand Diels-Alder (iEDDA) reactions with tetrazine-functionalized partners and amine-mediated conjugation for site-specific labeling of biomolecules.
- Enables rapid iEDDA bioorthogonal chemistry for fast conjugation.
- Terminal primary amine allows amide bond formation with carboxyl groups.
- Three-unit PEG spacer improves aqueous solubility and reduces steric hindrance.
- Suitable for site-specific labeling and bioconjugation workflows.
- Typically supplied as a small solid quantity for laboratory use.
Medchemexpress LLC M-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 10 G
m-PEG5-Br is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, with one ligand targeting an E3 ubiquitin ligase and the other targeting the protein of interest. These compounds function by exploiting the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
Medchemexpress LLC M-PEG3-SH | 31521-83-2 | 98.95% | 180.27 | 10 G
m-PEG3-SH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are molecules designed to degrade target proteins by leveraging the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Designed to selectively degrade target proteins
![Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | MFCD28505530 | 95.0% | 234.25 g/mol | C8H18N4O4 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202088.png-250.jpg)
Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | MFCD28505530 | 95.0% | 234.25 g/mol | C8H18N4O4 | 10 MG
Aminooxy-PEG3-azide is a PEG-based bifunctional linker containing an aminooxy (oxyamine) group and an azide group. It is used as a non-cleavable three-unit PEG spacer for antibody-drug conjugate (ADC) and PROTAC synthesis, and as an azide reagent for click chemistry reactions such as CuAAC and SPAAC.
- Bifunctional aminooxy and azide groups for oxime ligation and click chemistry.
- Non-cleavable three-unit PEG spacer suitable for ADC and PROTAC linker installation.
- Purity 95.0% and molecular weight 234.25 g/mol.
- Appearance colorless to light yellow liquid for easy handling.
- Storage: pure form -20°C (stable 3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Available in small pack sizes, including 10 mg for small-scale synthesis.
Medchemexpress LLC Bis(1-chloro-2-propyl) phosphate | 789440-10-4 | MFCD31579781 | 251.04 g/mol | C6H13Cl2O4P | 1 MG
Bis(1-chloro-2-propyl) phosphate is an organophosphate research chemical and a metabolite reference standard used in studies of organophosphate flame retardants and their metabolites. It is supplied as a small laboratory quantity for analytical and toxicological research.
- Chemical identifiers: CAS 789440-10-4; formula C6H13Cl2O4P; molecular weight 251.04 g/mol.
- Used as an analytical standard for metabolite identification and biomonitoring studies.
- Provided as a 1 mg laboratory sample suitable for analytical assays and method development.
- Intended for laboratory research use; consult the safety data sheet for handling and hazard information.
Medchemexpress LLC Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH | 2351103-63-2 | 93.9% | 10 MG
Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. It is for research use only.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide based cereblon ligand
- Linker used in PROTAC technology
- Targets Cereblon
- For research use only
Medchemexpress LLC 2',3'-O-Isopropylideneuridine | 362-43-6 | 99.9% | 284.27 | 10 G
2',3'-O-Isopropylideneuridine is a modified uridine. It can be used in the research of viral diseases such as cytomegalovirus and varicella-zoster virus.
- Modified uridine
- Can be used in the research of viral diseases
- Effective against cytomegalovirus
- Effective against varicella-zoster virus
Medchemexpress LLC 5-Bromo-2-trifluoromethylpyridine | 436799-32-5 | 99.7% | C6H3BrF3N | 10 G
5-Bromo-2-trifluoromethylpyridine is a biochemical reagent suitable for life science research. It can be used as a biological material or organic compound. This product appears as a white to off-white solid.
- For research use only
- Not sold to patients
- Solid, white to off-white appearance
- High purity (99.7%)
Medchemexpress LLC Perfluorophenyl 3-(2-(2-(2-(1,3-dioxoisoindolin-2-yloxy)ethoxy)ethoxy)ethoxy)propanoate | 2101206-87-3 | >96.0% | 533.4 g/mol | C23H20F5NO8 | 10 MG
NHPI-PEG3-C2-Pfp ester is a noncleavable, trifunctional 3-unit polyethylene glycol (PEG) linker bearing an N-hydroxyphthalimide (NHPI) group and a perfluorophenyl (Pfp) activated ester. It is used for bioconjugation and in the synthesis of antibody-drug conjugates (ADCs). Intended for research use only.
- Noncleavable 3-unit PEG linker
- NHPI functional group for site-specific conjugation
- Perfluorophenyl activated ester for amine coupling
- Molecular weight about 533.4 g/mol; formula C23H20F5NO8
- Purity greater than 96%
- Intended for research use only, not for human or animal use
Medchemexpress LLC N-Boc-C1-PEG3-C3-NH2 | 194920-62-2 | 320.42 | 10 G
N-Boc-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC 2-Cyclopenten-1-one, 3-methyl- | 2758-18-1 | 99.12% | 96.13 | 10 G
3-Methyl-2-cyclopenten-1-one is an endogenous metabolite provided for research use. It is a light yellow to brown liquid with a molecular weight of 96.13.
- Intended for research and analytical use.
- Available in various quantities including 10 gram.
- Stored at -20°C for 3 years or 4°C for 2 years in pure form.
- Stored at -80°C for 6 months or -20°C for 1 month in solvent.
- Appearance is a light yellow to brown liquid.
Medchemexpress LLC SB290157 trifluoroacetate | 1140525-25-2 | MFCD04974198 | 99.8% | 526.51 g/mol | C24H29F3N4O6 | 10 MG
SB290157 trifluoroacetate is a selective antagonist of the complement C3a receptor (C3aR) used in research to probe C3a-mediated signaling. The compound is supplied as the trifluoroacetate salt, with reported in vitro potency (IC50 200 nM) and high chemical purity for laboratory studies.
- Selective C3a receptor antagonist with reported IC50 of 200 nM.
- Supplied as the trifluoroacetate salt.
- Molecular formula C24H29F3N4O6; molecular weight 526.51 g/mol.
- High purity (≈99.8%).
- Available in milligram-scale packages for laboratory use.
- For research use only; not for human or veterinary use.
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