Heptane
![Medchemexpress LLC Acetamide, N-[3-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl] | 1401731-54-1 | 99.8% | 266.30 g·mol⁻¹ | C15H14N4O | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000227822.png-250.jpg)
Medchemexpress LLC Acetamide, N-[3-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl] | 1401731-54-1 | 99.8% | 266.30 g·mol⁻¹ | C15H14N4O | 50 MG
N-(3-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl)acetamide is a research-grade small-molecule inhibitor of casein kinase 1 (CK1) and checkpoint kinase 1 (CHK1), supplied as a solid for laboratory research use. It has CAS 1401731-54-1, molecular formula C15H14N4O, molecular weight 266.30 g·mol⁻¹, and reported purity of 99.77%.
- High chemical purity suitable for biochemical and cellular assays.
- Solid form enables straightforward handling and storage.
- Targets CK1 and CHK1 for kinase pathway studies.
- Available in small research quantities for assay development.
Medchemexpress LLC Zanzalintinib | 2367004-54-2 | 99.91% | 528.53 | 50 MG
Zanzalintinib (XL092) is an orally active, ATP-competitive inhibitor of multiple receptor tyrosine kinases (RTKs) including MET, VEGFR2, AXL, and MER. It exhibits anti-tumor activity and has potential for research in kinase-dependent diseases and conditions.
- Orally active, ATP-competitive inhibitor
- Targets MET, VEGFR2, AXL, and MER
- Exhibits anti-tumor activity
- Potential for kinase-dependent diseases and conditions research
Medchemexpress LLC Cyclosomatostatin | 84211-54-1 | 99.8% | 779.97 | 1 MG
Cyclosomatostatin is a potent somatostatin (SST) receptor antagonist. It can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size, and sphere-formation in colorectal cancer (CRC) cells.
- Potent somatostatin (SST) receptor antagonist
- Inhibits somatostatin receptor type 1 (SSTR1) signaling
- Decreases cell proliferation
- Decreases ALDH+ cell population size
- Decreases sphere-formation in colorectal cancer (CRC) cells
- Target for somatostatin receptor
- Involved in GPCR/G protein and neuronal signaling pathways
Medchemexpress LLC Cyclosomatostatin | 84211-54-1 | 99.76% | 779.97 | 5 MG
Cyclosomatostatin is a potent somatostatin (SST) receptor antagonist that inhibits somatostatin receptor type 1 (SSTR1) signaling. It has been shown to decrease cell proliferation, ALDH+ cell population size, and sphere-formation in colorectal cancer (CRC) cells.
- Potent somatostatin receptor antagonist
- Inhibits somatostatin receptor type 1 (SSTR1) signaling
- Decreases cell proliferation
- Reduces ALDH+ cell population size
- Reduces sphere-formation in colorectal cancer (CRC) cells
Medchemexpress LLC Sappanchalcone | 94344-54-4 | 99.5% | C16H14O5 | 5 MG
Sappanchalcone is a flavonoid isolated from *Caesalpinia sappan L.*, which induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells. It is intended for research use only.
- Flavonoid isolated from *Caesalpinia sappan L.*
- Induces caspase-dependent and AIF-dependent apoptosis
- Shows statistically significant effect on HCT116 cells
- Reduces MMP with significant increase in ROS levels
- Triggers phosphorylation of p53
- Inhibits LPS stimulated TNF alpha production in Balb/c mouse peritoneal macrophages
Medchemexpress LLC 3'-Hydroxypuerarin | 117060-54-5 | 432.38 | 20 MG
3'-Hydroxypuerarin is an isoflavone isolated from the roots of Pueraria lobata (Willd.) Ohwi. It acts as an antioxidant, exhibiting marked ONOO(-), NO•, and total ROS scavenging activities.
- Isolated from Pueraria lobata (Willd.) Ohwi.
- Acts as an antioxidant.
- Exhibits marked ONOO(-) scavenging activity.
- Exhibits marked NO• scavenging activity.
- Exhibits marked total ROS scavenging activities.
Medchemexpress LLC SR15006 | 2505001-54-5 | 99.90% | 385.87 | 100 MG
SR15006 is an inhibitor of Krüppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells. In vitro studies demonstrated that SR15006 (1 μM or 10 μM) causes a significant reduction in the levels of tested cyclins over 72 hours in DLD-1 CRC cells. This product is for research use only.
- Inhibits Krüppel-like factor 5 (KLF5)
- Exhibits IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells
- Reduces cyclin levels in DLD-1 CRC cells
- For research use only
Medchemexpress LLC 2-Propenamide, 3-(3-chlorophenyl)-N-[2-[4-(methylsulfonyl)-1-piperazinyl]-2-oxoethyl]-, (2E)- | 2505001-54-5 | 99.9% | 385.87 | 50 MG
SR15006 is an inhibitor of Krüppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells. It causes a significant reduction in the levels of tested cyclins over 72 hours in DLD-1 CRC cells at concentrations of 1 μM or 10 μM. This product is for research use only.
- Inhibits Krüppel-like factor 5 (KLF5)
- IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells
- Causes a significant reduction in cyclin levels over 72 hours
- Appearance: solid, white to off-white
eMolecules AstaTech / 2-ETHYNYLTETRAHYDROFURAN / 0.1g / 503283468 / AT10094 / 95.000 / 76928-54-6 / MFCD26853295 / 96.129 / C6H8O
AstaTech / 2-ETHYNYLTETRAHYDROFURAN / 0.1g / 503283468 / AT10094 / 95.000 / 76928-54-6 / MFCD26853295 / 96.129 / C6H8O
Sigma Aldrich Fine Chemicals Biosciences Heptane biotech. grade, >=99% | 142-82-5 | MFCD00009544 | 1L
Heptane biotech. grade, >=99% | Purity: >=99% | Mol Wt: 100.2 | 142-82-5 | MFCD00009544 | 1L
Medchemexpress LLC Isocolumbin | 471-54-5 | 1 MG
Isocolumbin is a diterpenoid isolated from Jateorhiza palmate Miers (Colombo root).
- Diterpenoid isolated from Colombo root.
- Acts as an endogenous metabolite.
- Involves the metabolic enzyme/protease pathway.
![Medchemexpress LLC 2-cyano-N-{[(3,4-dichlorophenyl)carbamothioyl]amino}acetamide | 656222-54-7 | MFCD00119122 | 99.8% | 303.17 | C10H8Cl2N4OS | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237141.png-250.jpg)
Medchemexpress LLC 2-cyano-N-{[(3,4-dichlorophenyl)carbamothioyl]amino}acetamide | 656222-54-7 | MFCD00119122 | 99.8% | 303.17 | C10H8Cl2N4OS | 25MG
iKIX1 is a small-molecule antifungal research compound that disrupts the interaction between the KIX domain of the mediator subunit CgGal11A and the activation domain of CgPdr1, and it resensitizes azole-resistant Candida glabrata in vitro. The compound has formula C10H8Cl2N4OS and a molecular weight of 303.17 g·mol⁻¹; it is supplied for research use only.
- Inhibits KIX-activation domain interaction (IC50 190.2 μM; Ki 18 μM).
- Resensitizes azole-resistant Candida glabrata in vitro.
- Supplied for research use only; not for clinical use.
- High purity (99.8% as reported by manufacturer).
- Stable as powder at -20°C for up to 3 years; in solvent stored at -80°C (6 months) or -20°C (1 month).
- Available as solid and as DMSO solution formulations for convenient handling.
Medchemexpress LLC rel-Zotatifin | 2098191-54-7 | 97.3% | 487.56 g/mol | C28H29N3O5 | 5 MG
rel-Zotatifin is a research-grade small-molecule inhibitor of the eukaryotic initiation factor eIF4A, supplied as the racemic isomer for laboratory studies. It is characterized by a molecular formula of C28H29N3O5, molecular weight of 487.56 g/mol, and high purity suitable for biochemical and cellular assays.
- Racemic isomer with eIF4A inhibitory activity.
- High supplied purity for research applications.
- Supplied as a small, convenient 5 mg package for screening and assay development.
- Suitable for biochemical and cell-based translation studies.
- Molecular weight and formula provided for analytical confirmation.