Tetrahydrofuran
Medchemexpress LLC L-745870 hydrochloride | 1173023-36-3 | 99.9% | C18H20Cl2N4 | 10MG
L-745870 hydrochloride is the hydrochloride salt of a selective dopamine D4 receptor antagonist used in pharmacology research. It is brain-penetrant, orally active, and is employed to investigate D4 receptor activity and related neuropharmacological effects.
- Potent and selective dopamine D4 receptor antagonist (Ki 0.43 nM).
- Brain-penetrant and orally active for in vivo studies.
- High chemical purity suitable for research use (99.9%).
- Available as a solid or as a DMSO solution for flexibility in assays.
- Offered in multiple small-scale package sizes for preclinical experiments.
Medchemexpress LLC Nelonicline | 1026134-63-3 | 99.8% | 313.42 g/mol | C17H19N3OS | 10 MG
Nelonicline is an orally active, selective agonist of the α7 nicotinic acetylcholine receptor supplied as a research reagent for preclinical and in vitro studies. It has molecular formula C17H19N3OS and molecular weight 313.42 g/mol. For research use only; not for clinical or diagnostic applications.
- Selective α7 nicotinic acetylcholine receptor agonist suitable for receptor pharmacology studies.
- Orally active small molecule compatible with in vivo and in vitro experiments.
- Available as a 10 MG solid and as a 10 mM solution in DMSO for assay use.
- High-purity research compound appropriate for preclinical studies.
- Supplied for research use only, not intended for therapeutic use.
Medchemexpress LLC BDP9066 | 2226507-04-4 | 98.2% | 348.44 | 10 MG
BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor. It has an IC50 of 64 nM for MRCKβ in SCC12 cells, and Ki values of 0.0136 nM and 0.0233 nM for MRCKα/β respectively. It demonstrates a therapeutic effect on skin cancer by reducing substrate phosphorylation. This product is for research use only.
- Targets MRCKα (0.0136 nM (Ki)) and MRCKβ (0.0233 nM (Ki))
- Shows antiproliferative effects with greatest activity in hematologic cancer cells
- Inhibits MLC phosphorylation and blocks SCC12 squamous cell carcinoma motility and invasion
- Topical application significantly decreases phosphorylated MRCKα S1003 staining and tumor volumes
Sigma Aldrich Fine Chemicals Biosciences 2 Methyltetrahydrofuran 3 1KG
2 Methyltetrahydrofuran 3 1KG
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran suitable for HPLC, >=99.9%, inhibitor-free | 109-99-9 | MFCD00005356 | 4X4L
Tetrahydrofuran suitable for HPLC, >=99.9%, inhibitor-free | Purity: >=99.9% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 4X4L
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran | 109-99-9 | MFCD00005356 | 2l
Tetrahydrofuran | Purity: 99% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 2l
Medchemexpress LLC MPT0B392 | 1346169-92-3 | 99.6% | 404.44 g/mol | C19H20N2O6S | 100 MG
MPT0B392 is an orally active quinoline-derived microtubule-depolymerizing agent that activates c-Jun N-terminal kinase (JNK) and induces apoptosis. It inhibits tubulin polymerization and causes mitotic arrest, making it useful in cell biology and oncology research investigating microtubule dynamics and drug resistance mechanisms.
- High purity (≈99.6%) suitable for research assays.
- Solid powder, light yellow to yellow appearance.
- Well-characterized molecular properties (C19H20N2O6S, 404.44 g/mol).
- Documented storage stability in powder and solution.
- Biological activity: tubulin depolymerizer, JNK activator, apoptosis inducer.
- Includes CAS number for unambiguous identification.
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran anhydrous1L
Tetrahydrofuran (THf) is a saturated cyclic ether mainly used as an organic solvent. On long term storage it forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation. It constitutes the key fragment of various natural products (polyether antibiotics). THf forms double hydrate with hydrogen sulfide crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies.
Medchemexpress LLC Protogracillin | 54848-30-5 | 1 MG
Protogracillin is a steroidal saponin isolated from the plant Dioscorea zingiberensis Wright. Steroidal saponins found in the rhizomes of this plant have the potential to reduce the risk of cardiovascular diseases through anti-thrombotic action. It is intended for research use only and not for sale to patients.
- It is a steroidal saponin.
- It is isolated from Dioscorea zingiberensis Wright.
- It has potential anti-thrombotic action.
- It has shown cytotoxicity against human CCRF-CEM cells with an IC50 of 1.77 μM.
- Its purity is 99.00%.
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran contains 250 ppm BHT as inhibitor, ACS reagent, >=99.0% | 109-99-9 | MFCD00005356 | 2.5L
Tetrahydrofuran contains 250 ppm BHT as inhibitor, ACS reagent, >=99.0% | Purity: >=99.0% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 2.5L
Medchemexpress LLC GW406108X 10mg | 1644443-92-4 | 10 MG
Small-molecule research inhibitor of Kif15 and ULK1 that blocks autophagic flux and is used in cellular and biochemical studies to probe autophagy and kinesin-related pathways. CAS 1644443-92-4; molecular formula C20H11Cl2NO4; molecular weight 400.21 g/mol.
- Selective Kif15 ATPase inhibitor (IC50 0.82 μM).
- ATP-competitive ULK1 inhibitor (pIC50 6.37; ~427 nM).
- High purity solid for research (98.0% reported by supplier).
- Molecular formula C20H11Cl2NO4; molecular weight 400.21 g/mol.
- Recommended storage: powder at -20 °C for long term or 4 °C for short term; in solution store at -80 °C for extended periods.
Medchemexpress LLC PD-1/PD-L1-in-23 | 2597056-04-5 | C32H30BrCl2N3O6 | 10MG
PD-1/PD-L1-IN-23 is a small-molecule research compound that inhibits the PD-1/PD-L1 immune checkpoint pathway. Supplied as a solid powder in milligram-scale packaging, it is intended for in vitro and preclinical studies to probe PD-1/PD-L1 interactions in biochemical and cellular assays.
- High purity (>98%).
- Chemical formula C32H30BrCl2N3O6; molecular weight 703.41 g/mol.
- Supplied as a solid powder suitable for dissolution in common laboratory solvents.
- Intended for in vitro and preclinical research use; not for clinical or human use.
- Useful for studies of PD-1/PD-L1 interaction and checkpoint inhibition assays.
Medchemexpress LLC Ro5-3335 | 30195-30-3 | 99.5% | 259.69 | 10 MG
Ro5-3335 | 30195-30-3 | 99.5% | 259.69 | 10 MG
eMolecules 89160-04-3 | Ambeed | 21-Hydroxyhenicosanoic acid | 1g | 660582704 | A1195099 | 342.564 | C21H42O3
Ambeed | 21-Hydroxyhenicosanoic acid | 1g | 660582704 | A1195099 | 89160-04-3 | 342.564 | C21H42O3
![eMolecules 959704-59-7 | TERT-BUTYL (1-OXASPIRO[2.5]OCTAN-6-YL)CARBAMATE | MFCD22377855 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502179564.JPG-250.jpg)
eMolecules 959704-59-7 | TERT-BUTYL (1-OXASPIRO[2.5]OCTAN-6-YL)CARBAMATE | MFCD22377855 | 1g
AstaTech | TERT-BUTYL (1-OXASPIRO[2.5]OCTAN-6-YL)CARBAMATE | 1g | 603096395 | W19422 | 95.000 | 959704-59-7 | MFCD22377855 | 227.304 | C12H21NO3
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