Tetrahydrofuran
Medchemexpress LLC SU5214 | 186611-04-1 | 98.0% | 251.28 | 5 MG
SU5214 is a potent VEGFR2 inhibitor. It has been extracted from patent US5834504A and exhibits IC50s of 14.8 μM for FLK-1 and 36.7 μM for EGFR.
- Potent VEGFR2 inhibitor.
- Targets VEGFR.
- Acts on the Protein Tyrosine Kinase/RTK pathway.
- Soluble in DMSO at 100 mg/mL.
- Suitable for research purposes.
Medchemexpress LLC Rhodojaponin III | 26342-66-5 | 5 MG
Rhodojaponin III is a diterpenoid extracted from the leaves of Rhododendron molle. It exhibits anti-inflammatory activity, demonstrated by its IC50 of 7 μM against LPS-induced nitric oxide production in mouse RAW264.7 cells. This compound has a molecular weight of 368.46 and a chemical formula of C20H32O6. It typically appears as a white to off-white solid.
- Extracted from the leaves of Rhododendron molle
- Exhibits anti-inflammatory activity
- Has an IC50 of 7 μM against LPS-induced nitric oxide production in mouse RAW264.7 cells
- Molecular weight is 368.46
- Chemical formula is C20H32O6
- Appears as a white to off-white solid
- Intended for research use only
Medchemexpress LLC Deacylmetaplexigenin | 3513-04-0 | 1 MG
Deacylmetaplexigenin is a natural product and steroid, specifically a pregnane glycoside. This compound has been isolated from plants such as Asclepias incarnata, Cynanchum viminale, and Cynanchum rostellatum.
- Molecular weight: 380.5 g/mol
- XLogP3-AA: -0.4
- Hydrogen bond donors: 5
- Hydrogen bond acceptors: 6
- Rotatable bond: 1
- Topological polar surface area: 118 Ų
Medchemexpress LLC Specnuezhenide ((8E)-Nuezhenide) | 39011-92-2 | 686.66 | 5 MG
Specnuezhenide ((8E)-Nuezhenide) is a compound isolated from the fruits of *Ligustrum lucidum*. It demonstrates the ability to inhibit IL-1β-induced inflammation in chondrocytes by suppressing NF-κB and wnt/β-catenin signaling pathways. Additionally, Specnuezhenide exhibits anti-inflammatory effects in a rat model of osteoarthritis (OA).
- Isolated from *Ligustrum lucidum* fruits.
- Inhibits IL-1β-induced inflammation in chondrocytes.
- Exerts anti-inflammatory effects in osteoarthritis rat models.
- For research use only.
- Purity of 99.52%.
- Appears as a solid.
- Color is white to off-white.
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran ReagentPlu1L
Tetrahydrofuran (THf) is a saturated cyclic ether mainly used as an organic solvent. On long term storage it forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation. THf constitutes the key fragment of various natural products (polyether antibiotics). THf can form a double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1 4-diol is formed as an intermediate during the synthesis of THf. Hot THf is useful for the disSOLUTIONon of polyvinylidene chloride (PVDV).
Medchemexpress LLC Su 5214 | 186611-04-1 | MFCD01595259 | >98.0% | 10 MG
SU5214 is a small-molecule tyrosine kinase inhibitor reported to inhibit vascular endothelial growth factor receptor 2 (VEGFR2/FLK-1) and epidermal growth factor receptor (EGFR) in cell-free assays. It is used for biochemical studies and target validation involving VEGFR2/EGFR signaling pathways.
- Reported IC50 of 14.8 μM for VEGFR2 (cell-free assay).
- Reported IC50 of 36.7 μM for EGFR (cell-free assay).
- CAS number 186611-04-1.
- Molecular weight 251.285 g·mol⁻¹.
- Purity greater than 98% (HPLC) as supplied by chemical vendors.
- Supplied in small milligram quantities suitable for in vitro assays.
![Medchemexpress LLC N,N'-1,3-phenylenebis[2,3-dihydroxy-benzamide] | 368449-04-1 | 98.6% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000232665.png-250.jpg)
Medchemexpress LLC N,N'-1,3-phenylenebis[2,3-dihydroxy-benzamide] | 368449-04-1 | 98.6% | 50 MG
MST-312 (Telomerase Inhibitor IX) is a small-molecule telomerase inhibitor derived from epigallocatechin gallate (EGCG). It is supplied as a white to off-white solid for laboratory research in oncology and telomerase studies.
- Telomerase inhibitor for cancer research.
- Chemically modified derivative of epigallocatechin gallate (EGCG).
- Molecular formula C20H16N2O6 and molecular weight 380.35 g·mol⁻1.
- Purity 98.6%.
- Supplied as a solid with common solubility in DMSO for solution preparation.
eMolecules 24808-04-6 | Medchem Express | (-)-Epiafzelechin | 5mg | 713705081 | HY-N0943 | MFCD20260428 | 274.272 | C15H14O5
Ambeed | 9-(4-Bromophenyl)-36-di-tert-butyl-9H-carbazole | 1g | 525197143 | A363941 | 601454-33-5 | MFCD11617971 | 434.421 | C26H28BrN
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Medchemexpress LLC PF-00446687 free base | 862281-92-3 | 98.0% | 470.59 g/mol | C28H36F2N2O2 | 50 MG
PF-00446687 free base is a non-peptide, brain-penetrant small-molecule agonist of the melanocortin-4 receptor (MC4R) used in research on melanocortin signaling and central nervous system pharmacology. It is supplied as a powder for in vitro and in vivo studies and demonstrates low-nanomolar potency and selectivity.
- Selective melanocortin-4 receptor agonist with EC50 12 ± 1 nM.
- Binding affinity (Ki) approximately 27 ± 4 nM.
- Brain-penetrant, suitable for central nervous system studies.
- Provided as a powder with solubility in DMSO 62.5 mg/mL (ultrasonic recommended).
- Molecular formula C28H36F2N2O2 and molecular weight 470.59 g/mol.
- High purity by HPLC (≈98.0% per COA).
- Storage: powder -20°C (long-term) or 4°C (short-term).
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran inhibitor-free, suitable for HPLC, >=99.9% | 109-99-9 | MFCD00005356 | 100ML
Tetrahydrofuran inhibitor-free, suitable for HPLC, >=99.9% | Purity: >=99.9% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 100ML
eMolecules 1192-30-9 | TETRAHYDROFURFURYL BROMIDE | AstaTech | MFCD00016894 | 165.030 | C5H9BrO | 95.000 | BrCC1CCCO1 | 100g | 449775922
TETRAHYDROFURFURYL BROMIDE | AstaTech | 1192-30-9 | MFCD00016894 | 165.030 | C5H9BrO | 95.000 | BrCC1CCCO1 | 100g | 449775922
Medchemexpress LLC Naz2329 | 2809469-05-2 | 99.0% | 501.56 g/mol | C21H18F3NO4S3 | 25 MG
NAZ2329 is a small-molecule inhibitor of PTPRZ and PTPRG intended for research use. It is supplied as a 25 mg research sample and is characterized by high purity and defined physicochemical properties suitable for biochemical and in vivo studies.
- Inhibits PTPRZ and PTPRG activity.
- High purity: 99.02%.
- Molecular formula: C21H18F3NO4S3; molecular weight: 501.56 g/mol.
- Soluble in DMSO; in vitro solubility reported at 100 mg/mL.
- Provided as a 25 mg sample suitable for preliminary biochemical and in vivo assays.
Medchemexpress LLC L-Alanine, N-phosphono-, P→6-ester with 2-C-(4-aminopyrrolo[2,1-f]triazin-7-yl)... | 1911579-04-8 | 97.86% | 442.32 | 1 MG
GS-704277 is an alanine metabolite of Remdesivir. It is further hydrolyzed to GA-441524, a compound with antiviral activity. Remdesivir, a nucleoside analogue, is effective against SARS-CoV-2 (COVID-19) infection.
- Alanine metabolite of Remdesivir
- Further metabolized to GA-441524, which exhibits antiviral activity
- Related to Remdesivir, a nucleoside analogue effective against SARS-CoV-2 (COVID-19) infection
- Functions as a drug metabolite
- Involves the metabolic enzyme/protease pathway
eMolecules 805243-04-3 | Ambeed | 3-(Bis(benzyloxy)phosphoryl)propanoic acid | 1g | 525098833 | A181500 | MFCD08064320 | 334.308 | C17H19O5P
Ambeed | 3-(Bis(benzyloxy)phosphoryl)propanoic acid | 1g | 525098833 | A181500 | 805243-04-3 | MFCD08064320 | 334.308 | C17H19O5P
Medchemexpress LLC Onjisaponin B | 35906-36-6 | 99.1% | 10 MG
Onjisaponin B is a natural triterpenoid saponin isolated from Polygala tenuifolia with reported neuroprotective and autophagy-enhancing activity. It is used in cell-based and preclinical studies investigating protein aggregation, neurodegeneration, and inflammatory signaling.
- Natural triterpenoid saponin derived from Polygala tenuifolia.
- Inhibits NF-κB p65 and modulates inflammatory signaling.
- Enhances autophagy and promotes degradation of mutant α-synuclein and huntingtin.
- High purity solid powder (99.1%).
- Supplied as a 10 mg quantity suitable for research-scale assays.
- Intended for mechanistic studies and preclinical pharmacology models.