Tetrahydrofuran
Medchemexpress LLC PD-1/PD-L1-in-23 | 2597056-04-5 | C32H30BrCl2N3O6 | 10MG
PD-1/PD-L1-IN-23 is a small-molecule research compound that inhibits the PD-1/PD-L1 immune checkpoint pathway. Supplied as a solid powder in milligram-scale packaging, it is intended for in vitro and preclinical studies to probe PD-1/PD-L1 interactions in biochemical and cellular assays.
- High purity (>98%).
- Chemical formula C32H30BrCl2N3O6; molecular weight 703.41 g/mol.
- Supplied as a solid powder suitable for dissolution in common laboratory solvents.
- Intended for in vitro and preclinical research use; not for clinical or human use.
- Useful for studies of PD-1/PD-L1 interaction and checkpoint inhibition assays.
![eMolecules Ambeed / 21-Hydroxyhenicosanoic acid / 1g / 660582704 / A1195099 / / 89160-04-3 / [null] / 342.564 / C21H42O3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502444246.PNG-250.jpg)
eMolecules Ambeed / 21-Hydroxyhenicosanoic acid / 1g / 660582704 / A1195099 / / 89160-04-3 / [null] / 342.564 / C21H42O3
Ambeed / 21-Hydroxyhenicosanoic acid / 1g / 660582704 / A1195099 / / 89160-04-3 / [null] / 342.564 / C21H42O3
![eMolecules TERT-BUTYL (1-OXASPIRO[2.5]OCTAN-6-YL)CARBAMATE | 959704-59-7 | MFCD22377855 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502179564.JPG-250.jpg)
eMolecules TERT-BUTYL (1-OXASPIRO[2.5]OCTAN-6-YL)CARBAMATE | 959704-59-7 | MFCD22377855 | 1g
AstaTech | TERT-BUTYL (1-OXASPIRO[2.5]OCTAN-6-YL)CARBAMATE | 1g | 603096395 | W19422 | 95.000 | 959704-59-7 | MFCD22377855 | 227.304 | C12H21NO3
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Medchemexpress LLC 2-((5-((4-fluorophenyl)carbamoyl)pyrimidinyl)sulfanylmethyl)-4-(trifluoromethoxy)phenyl boronic acid | 1648843-04-2 | 98.7% | 25 MG
SX-682 (CAS 1648843-04-2) is an orally bioavailable small-molecule allosteric inhibitor of CXCR1 and CXCR2 investigated for oncology research. It blocks recruitment of immunosuppressive myeloid-derived suppressor cells to the tumor microenvironment and can enhance the activity of checkpoint inhibitors.
- Oral bioavailability and potent CXCR1/2 antagonism
- Useful for preclinical and clinical oncology research
- Blocks myeloid-derived suppressor cell recruitment to tumors
- Well-characterized chemical identity: CAS 1648843-04-2, C19H14BF4N3O4S
- Analytical purity typically >98% and supplied as a 25 MG vial
eMolecules Medchem Express / AZD5423 / 5mg / 506403637 / HY-108243 / / 1034148-04-3 / MFCD26142626 / 487.455 / C25H21F4N3O3
Medchem Express / AZD5423 / 5mg / 506403637 / HY-108243 / / 1034148-04-3 / MFCD26142626 / 487.455 / C25H21F4N3O3
Medchemexpress LLC Vebicorvir | 2090064-66-5 | 99.7% | 467.44 | 50 MG
Vebicorvir is a first-generation inhibitor of the hepatitis B virus (HBV) core protein. It effectively suppresses the formation of covalently closed circular DNA (cccDNA) in de novo infection models, with EC50 values ranging from 1.84 μM to 7.3 μM. This compound inhibits pgRNA, HBeAg, and HBsAg production.
- First-generation hepatitis B virus (HBV) core protein inhibitor.
- Suppresses cccDNA formation in de novo infection models.
- Inhibits pgRNA, HBeAg, and HBsAg production.
![Medchemexpress LLC 3-fluoro-N-[(E)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]benzamide | 352336-36-8 | 99.4% | C17H12FN3O2S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000258367.png-250.jpg)
Medchemexpress LLC 3-fluoro-N-[(E)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]benzamide | 352336-36-8 | 99.4% | C17H12FN3O2S | 10MG
HY-133511 (MLS000544460) is a selective, reversible inhibitor of Eya2 phosphatase used in biochemical and cellular research. It is supplied as a white to off-white solid (C17H12FN3O2S) with high reported purity and characterized potency for use in mechanism and preclinical studies.
- selective, reversible inhibition of Eya2 phosphatase
- high reported purity (99.42%) suitable for research assays
- characterized potency: Kd 2.0 μM and IC50 4 μM
- high solubility in DMSO (125 mg/mL) and formulatable for animal dosing
- powder storage stability: -20°C for up to 3 years
- white to off-white solid with molecular weight 341.36 g/mol
Medchemexpress LLC Bifenthrin | 82657-04-3 | 99.8% | 50 MG
Bifenthrin is a synthetic pyrethroid insecticide that prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, which disrupts neural function.
- Effective against *A. gambiae* and *C. quinquefasciatus*
- Demonstrates good lethality against susceptible and resistant mosquitoes
- Effectively inhibits blood sucking
- Suitable for development as a mosquito-removal netting material
Medchemexpress LLC Otaplimastat (SP-8203) | 1176758-04-5 | 98.1% | 534.61 | 100 MG
Otaplimastat (SP-8203) is a matrix metalloproteinase (MMP) inhibitor that competitively blocks N-methyl-D-aspartate (NMDA) receptor-mediated excitotoxicity. It also exhibits anti-oxidant activity and can be used for the research of brain ischemic injury.
- Protects neuronal cells against NMDA-induced cell death.
- Inhibits Ca2+ influx following activation of NMDA receptors.
- Suppresses H2O2-induced cell death and reactive oxygen species production.
- Prevents ischemic neuronal death in an occlusion model of MCA.
- Attenuates impairment of stroke-induced motor function.
Medchemexpress LLC Linzagolix | 935283-04-8 | 99.7% | 508.42 | 50 MG
Linzagolix is a potent, non-peptide, and orally active GnRH antagonist. It can be used for uterine fibroids, endometriosis, and adenomyosis research. For research use only.
- Potent, non-peptide, and orally active GnRH antagonist
- Used for uterine fibroids, endometriosis, and adenomyosis research
Medchemexpress LLC Ceftaroline | 189345-04-8 | 98.5% | 604.70 | C22H20N8O5S4 | 5 MG
Ceftaroline is an N-phosphono-type cephalosporin, the active metabolite form used in research to evaluate antibacterial activity against gram-positive and gram-negative organisms. It is supplied as a white to yellow solid for laboratory use and is suitable for in vitro and preclinical assays.
- Antibacterial cephalosporin active metabolite.
- Suitable for in vitro and preclinical research.
- Supplied as a solid, white to yellow appearance.
- Available in small vial sizes for assay work.
- High reported purity (98.5%).
- Molecular weight 604.70.
Medchemexpress LLC Pelcitoclax | 1619923-36-2 | 99.7% | 1281.85 | 1 ML
Pelcitoclax (APG-1252) is a potent Bcl-2/Bcl-xl inhibitor with antineoplastic and pro-apoptotic effects. In vitro, APG-1252 changes to the reactive metabolite named APG-1252-M1, which has remarkable antitumor effects in acute myeloid leukemia. Pelcitoclax treatment inhibits xenograft tumor growth more obviously than other groups. In an animal model using BALB/c athymic nude mice, intravenous injection of Pelcitoclax once a day for 10 days inhibited xenograft tumor growth.
Medchemexpress LLC AZ12601011 | 2748337-86-0 | 99.8% | 100 MG
AZ12601011 is an orally active, selective TGFBR1 (ALK5) kinase inhibitor intended for laboratory research. It inhibits SMAD2 phosphorylation (IC50 = 18 nM; Kd = 2.9 nM), has demonstrated antitumor activity in preclinical models, and is provided with high analytical purity for biochemical assays.
- Selective TGFBR1 inhibition with low-nanomolar potency.
- Inhibits SMAD2 phosphorylation in signaling assays.
- High analytical purity suitable for biochemical studies.
- Supplied as a 100 mg solid for convenient dosing.
- For research use only; not for human or clinical use.
Medchemexpress LLC MPT0B392 | 1346169-92-3 | MFCD32174244 | 99.6% | 404.44 | C19H20N2O6S | 50 MG
MPT0B392 is an orally active quinoline-derived microtubule-depolymerizing agent that inhibits tubulin polymerization, activates c-Jun N-terminal kinase (JNK), and induces apoptosis. It is used in cellular assays and preclinical models to study microtubule dynamics and apoptosis signaling pathways.
- Inhibits tubulin polymerization and induces mitotic arrest.
- Activates c-Jun N-terminal kinase (JNK) and promotes apoptosis.
- High purity (99.6%) for reliable experimental results.
- Soluble in DMSO (≈100 mg/mL) for convenient formulation.
- Solid, light yellow appearance for easy inspection.
- Stable as powder at -20°C for up to 3 years.
Medchemexpress LLC N-vanillyldecanamide | 31078-36-1 | MFCD01233545 | 99.9% | 307.43 g·mol⁻¹ | C18H29NO3 | 10 MG
N-Vanillyldecanamide is a capsaicinoid research chemical (CAS 31078-36-1) isolated from the fruits of Capsicum annuum. It has been reported to reduce the radical length of Lactuca sativa seedlings in a dose-dependent manner. The compound is supplied for laboratory research use with supporting documentation for handling and analysis.
- High purity (99.86%) suitable for analytical and biological studies.
- Molecular formula C18H29NO3 and molecular weight 307.43 g·mol⁻¹.
- Supplied in small laboratory quantities, including a 10 mg pack size.
- Available as a solid and as 10 mM solutions in DMSO for convenience.
- Storage: keep at 4°C and protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
- Typical applications include capsaicinoid activity studies, plant physiology research, and structure-activity investigations.
- Product documentation includes datasheet, COA, and SDS for quality and safety reference.