Tetrahydrofuran
Medchemexpress LLC Az12601011 | 2748337-86-0 | 99.8% | 50 MG
AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor (also inhibits ALK4 and ALK7) used as a research reagent to study TGF-β signaling and tumor models. It inhibits SMAD2 phosphorylation with reported potency (IC50 18 nM; Kd 2.9 nM) and has shown antitumor activity in vivo. High-purity powder and DMSO stock solutions are available.
- Selective TGFBR1, ALK4, and ALK7 inhibition.
- Biochemical potency: IC50 18 nM; Kd 2.9 nM.
- High purity (99.78%).
- Available as powder and DMSO solution for in vitro studies.
- Recommended storage: powder -20°C for long term, and solutions -80°C.
Medchemexpress LLC Tmx-4100 | 2367619-63-2 | 98.2% | C11H10N4O2S | 10MG
TMX-4100 is a research small-molecule described as a PDE6D degrader. It is supplied as a solid and as a DMSO solution, with molecular formula C11H10N4O2S and a reported purity of 98.18%. Intended for laboratory research use; consult the datasheet and COA for handling, storage, and batch-specific information.
- PDE6D degrader activity useful for protein degradation studies.
- Available as solid powder and as a 10 mM solution in DMSO.
- High reported purity (98.2%) for consistent experimental results.
- Comes with datasheet and certificate of analysis for batch verification.
- White to off-white solid appearance; suitable for standard laboratory handling.
Medchemexpress LLC BMS-1001 hydrochloride | 2113650-04-5 | 98.0% | 10 MG
BMS-1001 hydrochloride is a small-molecule PD-L1/PD-1 immune checkpoint inhibitor supplied for research use. It binds human PD-L1 and blocks PD-1/PD-L1 interaction, and is used in immunology and cancer research assays.
- Small-molecule PD-L1/PD-1 inhibitor for research use.
- Reported IC50 of 2.25 nM in HTRF binding assay.
- Available as solid and solution forms; common solid sizes include 5 mg-100 mg.
- Typical purity approximately 98.0% by supplier assay.
- Molecular weight 631.11 g/mol and formula C35H35ClN2O7.
Medchemexpress LLC L-745870 hydrochloride | 1173023-36-3 | 99.9% | C18H20Cl2N4 | 10MG
L-745870 hydrochloride is the hydrochloride salt of a selective dopamine D4 receptor antagonist used in pharmacology research. It is brain-penetrant, orally active, and is employed to investigate D4 receptor activity and related neuropharmacological effects.
- Potent and selective dopamine D4 receptor antagonist (Ki 0.43 nM).
- Brain-penetrant and orally active for in vivo studies.
- High chemical purity suitable for research use (99.9%).
- Available as a solid or as a DMSO solution for flexibility in assays.
- Offered in multiple small-scale package sizes for preclinical experiments.
Medchemexpress LLC Arotinolol | 68377-92-4 | 99.9% | 10 MG
Arotinolol (CAS 68377-92-4) is a nonselective alpha and beta adrenergic receptor blocker used in research to study cardiovascular pharmacology and receptor binding. It is supplied as a research-grade chemical with defined purity and chemical identifiers.
- Nonselective alpha/beta-adrenergic receptor blocker
- Used in cardiovascular and receptor pharmacology research
- Chemical formula C15H21N3O2S3 and molecular weight 371.54 g/mol
- Reported high purity of 99.93%
- Provided as a 10 mg research-grade solid for analytical studies