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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran inhibitor-
Tetrahydrofuran (THf) is widely employed as a solvent. It constitutes the key fragment of various natural products (polyether antibiotics). THf forms a double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1 4-diol is formed as an intermediate during the synthesis of THf. Hot THf is useful for the disSOLUTIONon of polyvinylidene chloride (PVDV).
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Chemscene ChemScene | (R)-Tetrahydrofuran-2-yl-methylamine | 10G | CS-W011317 | 0.98 | 7202-43-9| MFCD00192476 | 101.15
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ChemScene | (R)-Tetrahydrofuran-2-yl-methylamine | 10G | CS-W011317 | 0.98 | 7202-43-9| MFCD00192476 | 101.15
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Sigma Aldrich Fine Chemicals Biosciences 2-Methyltetrahydrofuran BioRenewable, ReagentPlus(R), >=99.5%, contains 150-400 ppm BHT as stabilizer | 96-47-9 | MFCD00005367 | 4X4L
2-Methyltetrahydrofuran BioRenewable, ReagentPlus(R), >=99.5%, contains 150-400 ppm BHT as stabilizer | Purity: >=99.5% | Mol Wt: 86.13 | 96-47-9 | MFCD00005367 | 4X4L
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Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran | 109-99-9 | MFCD00005356 | 1 L
Tetrahydrofuran | Purity: 99% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 1 L
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SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES TETRAHYDROFURAN 1L LICHROSOLV
NC2025278 TETRAHYDROFURAN 1L LICHROSOLV
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Medchemexpress LLC SU5214 | 186611-04-1 | 251.28 | 100 MG
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SU5214 is a potent VEGFR2 inhibitor. It is extracted from patent US5834504A and is suitable for research use. It acts on Protein Tyrosine Kinase/RTK pathway.
- Potent VEGFR2 inhibitor
- Target for VEGFR
- Inhibits FLK-1 with an IC50 of 14.8 μM
- Inhibits EGFR with an IC50 of 36.7 μM
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Medchemexpress LLC Nerigliatin | 1245603-92-2 | 99.9% | 432.43 g/mol | C22H20N6O4 | 50 MG
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Nerigliatin is an orally active glucokinase activator supplied for research and analytical use. It has been studied for glucose-lowering effects in type 2 diabetes models and is associated with peripheral nerve degeneration in preclinical reports. The compound is provided as a high-purity solid for laboratory experiments.
- Orally active glucokinase activator.
- Intended for research and analytical applications.
- High purity (reported 99.94%).
- Molecular formula C22H20N6O4; molecular weight 432.43 g/mol.
- Available as a 50 mg solid package.
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Medchemexpress LLC CSF1R-IN-1 | 2095849-04-8 | MFCD31813597 | 98.0% | 479.45 g/mol | C25H20F3N5O2 | 100 MG
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CSF1R-IN-1 is a potent small-molecule inhibitor of the colony stimulating factor 1 receptor (CSF1R) with subnanomolar enzymatic potency (IC50 = 0.5 nM). It has demonstrated good intestinal permeability and favorable oral pharmacokinetics in mice, supporting its use in preclinical in vivo pharmacology studies related to tumor-associated macrophage biology, cancer, and inflammation research.
- Potent CSF1R inhibition (IC50 = 0.5 nM).
- Suitable for preclinical in vivo pharmacology studies.
- Demonstrates good intestinal permeability in Caco-2 assays.
- Favorable oral pharmacokinetic profile in mice.
- Available in solid and DMSO solution formats for dosing flexibility.
- High reported purity for research use.
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Medchemexpress LLC Rifalazil 100mg | 129791-92-0 | 100MG
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Rifalazil (KRM-1648 ABI-1648) a rifamycin derivative inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the -subunit in RNA polymerase[1 Rifalazil (KRM-1648 ABI-1648) is an antibiotic exhibits high potency against mycobacteria gram-positive bacteria Helicobacter pylori C pneumoniae and C trachomatis with MIC values from 0 00025 to 0 0025 g/ml[3 Rifalazil (KRM-1648 ABI-1648) has the potential for the treatment of Chlamydia infection Clostridium difficile associated diarrhea (CDAD) and tuberculosis (TB)[2
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Medchemexpress LLC Eya2 phosphatase inhibitor | 352336-36-8 | 99.4% | 341.36 g/mol | C17H12FN3O2S | 5 MG
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MLS000544460 is a research-grade small molecule that selectively and reversibly inhibits the Eya2 phosphatase. It reduces Eya2-mediated cell migration and has reported anti-cancer activity. The compound is supplied as a powder and as DMSO solutions, is characterized by high purity, and is intended for laboratory research use only.
- Selective, reversible inhibition of Eya2 phosphatase.
- Reported Kd ≈ 2.0 μM and IC50 ≈ 4 μM for target engagement.
- High purity (~99.4%) suitable for biochemical and cell-based assays.
- Available as powder and as ready-to-use DMSO solutions.
- Stable when stored under recommended conditions for research reagents.
- Supplied with datasheet, certificate of analysis, and safety data sheet.
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Medchemexpress LLC Remdesivir metabolite | 1911579-04-8 | 99.6% | C15H19N6O8P | 10MG
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GS-704277 is an alanine metabolite of remdesivir used as a research reference standard for antiviral metabolism and analytical studies. It is intended for metabolite identification, pharmacokinetic investigations, and development or validation of chromatographic and mass-spectrometric assays.
- High stated purity suitable for analytical applications.
- Molecular formula and weight provided for confirmation and reporting.
- Available in small research-scale pack sizes for bench studies.
- Useful for metabolite identification and pharmacokinetic work.
- Compatible with LC-MS and HPLC analytical workflows.
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Medchemexpress LLC Tmx-4100 | 2367619-63-2 | 98.2% | C11H10N4O2S | 10MG
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TMX-4100 is a research small-molecule described as a PDE6D degrader. It is supplied as a solid and as a DMSO solution, with molecular formula C11H10N4O2S and a reported purity of 98.18%. Intended for laboratory research use; consult the datasheet and COA for handling, storage, and batch-specific information.
- PDE6D degrader activity useful for protein degradation studies.
- Available as solid powder and as a 10 mM solution in DMSO.
- High reported purity (98.2%) for consistent experimental results.
- Comes with datasheet and certificate of analysis for batch verification.
- White to off-white solid appearance; suitable for standard laboratory handling.
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Medchemexpress LLC (E)-1-(4-methoxyphenyl)-3-(4-morpholin-4-yl-6-nitroquinolin-2-yl)prop-2-en-1-one | 2313528-04-8 | 97.0% | C23H21N3O5 | 10MG
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hnRNPK-IN-1 is a small-molecule ligand that binds heterogeneous nuclear ribonucleoprotein K (hnRNPK), disrupting hnRNPK interaction with the c-myc promoter to inhibit c-myc transcription and induce apoptosis in cell-based assays. Binding affinities were measured by SPR and MST, and the compound is supplied as a solid for research use.
- Binds hnRNPK and disrupts hnRNPK-c-myc promoter interaction.
- Inhibits c-myc transcription and induces apoptosis in HeLa cell assays.
- Measured binding affinities: SPR Kd 4.6 μM, MST Kd 2.6 μM.
- High purity (97.0%) solid, brown to orange in appearance.
- Soluble in DMSO (~5 mg/mL) with warming and sonication.
- Store powder at -20°C (long-term) and solvent solutions at -80°C when possible.
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Sigma Aldrich Fine Chemicals Biosciences Linalool oxide natural, >=95% | 60047-17-8 | MFCD00053543 |
Linalool oxide natural, >=95% | Purity: >=95% | Mol Wt: 170.25 | 60047-17-8 | MFCD00053543 |
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Medchemexpress LLC Ac9-25 | 284040-76-2 | 98.1% | 2183.33 | 1 MG
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Ac9-25 is a N-terminal peptide of Annexin I that functions as a formyl peptide receptor (FPR) agonist. It activates neutrophil NADPH oxidase through FPR.
- N-terminal peptide of Annexin I
- Functions as a formyl peptide receptor (FPR) agonist
- Activates neutrophil NADPH oxidase
- Formula: C99H143N23O33
- Sequence: Ac-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys
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