Prenol lipids
Medchemexpress LLC (rel)-AR234960 | 1408311-94-3 | HY-120006A | 98.95% | 555.62 | 10 MG
(rel)-AR234960 is a selective and competitive agonist of the G protein-coupled receptor MAS. It activates the downstream ERK1/2 signaling pathway, leading to the expression of connective tissue growth factor (CTGF) and its downstream collagen subtype genes. This compound promotes collagen synthesis in cardiac fibroblasts via the MAS-ERK1/2-CTGF pathway and exacerbates extracellular matrix remodeling. It regulates the expression of cardiac fibrosis-related genes and can be utilized in heart failure research.
- Selective and competitive MAS receptor agonist
- Activates ERK1/2 signaling pathway
- Induces CTGF and collagen gene expression
- Promotes collagen synthesis in cardiac fibroblasts
- Regulates cardiac fibrosis-related genes
- Useful in heart failure research
TARGETMOL CHEMICALS INC BETA-TOCOPHEROL 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Beta-Tocopherol shows effect on human erythroleukemia cell (HEL) adhesion induced by phorbol 12-myristate 13-acetate (PMA). purity: 99%
Medchemexpress LLC Vitamin K1 (Standard) | 84-80-0 | MFCD00214063 | 450.70 | 50 MG
Vitamin K1 (Standard) is the analytical standard of Vitamin K1, intended for research and analytical applications. It is a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
- Analytical standard, reference standard supplied assay.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Endogenous metabolite.
- Initial source: Plants, other families, Human gut microbiota, Microorganisms.
- Structure classification: Quinones, Naphthalene quinones.
Medchemexpress LLC Pyridoxine | 8059-24-3 | MFCD00006335 | 100.0% | 169.18 g/mol | C8H11NO3 | 10 MG
Pyridoxine (vitamin B6) is a water-soluble vitamin and enzymatic cofactor involved in amino acid, lipid, and neurotransmitter metabolism. Supplied as a high-purity research reagent, this material is intended for laboratory and analytical use and is not for human or clinical applications.
- High-purity reagent suitable for biochemical assays and analytical methods.
- Water-soluble vitamin and cofactor in metabolic reactions.
- Suitable for cell studies and enzymology experiments.
- Supplied in a 10 mg package for small-scale laboratory use.
- Not for human consumption; intended for research use only.
Medchemexpress LLC Vitamin D Receptor/V 10ug
Vitamin D receptor (VDR) protein is the nuclear receptor of calcitriol which translocates to the nucleus after binding vitamin D3 thereby coordinating cellular activities VDR forms a heterodimer with RXR binds to DNA response elements and initiates the transcription of vitamin D3-responsive genes Vitamin D Receptor/VDR Protein Mouse (sf9 His) is the recombinant mouse-derived Vitamin D Receptor/VDR protein expressed by Sf9 insect cells with C-His labeled tag
Medchemexpress LLC Vosoritide (acetate) | 99.89% | 4162.78 | 25 MG
Vosoritide acetate is a natriuretic peptide receptor 2 (NPR2) agonist that promotes bone growth by acting on the proliferation and differentiation of chondrocytes. It is for research use only.
- Decreases NPR2 phosphorylation in chondrocytes.
- Improves chondrocyte differentiation and increases growth plate area.
- Reduces ERK1/2 activation in growth-plate chondrocytes.
- Improves skeletal parameters in Fgfr3 gain-of-function mutation mouse model.
Apexbio Technology LLC L-NMMA acetate 53308-83-1 25mg
L-NMMA acetate (CAS 53308-83-1) is a broad-spectrum inhibitor of nitric oxide synthases (NOS) exerting inhibitory effects on neuronal (nNOS) endothelial (eNOS) and inducible (iNOS) isoforms It demonstrates submicromolar to low micromolar inhibitory activity against rat nNOS human eNOS and mouse iNOS By selectively blocking NOS-mediated nitric oxide production L-NMMA acetate is widely utilized for dissecting nitric oxide-dependent signaling pathways with research applications spanning studies of tissue injury inflammatory responses and cardiovascular system functions
Medchemexpress LLC Rel-ACPT-I | 194918-76-8 | MFCD06795869 | 99.0% | 217.18 g·mol⁻1 | C8H11NO6 | 1 MG
rel-ACPT-I is a selective agonist of group III metabotropic glutamate receptors (mGluRs) with reported neuroprotective, anticonvulsant, and anxiolytic-like effects in preclinical studies. It is supplied as a high-purity research chemical for in vitro and in vivo pharmacology applications.
- Selective agonist of group III metabotropic glutamate receptors.
- Exhibits neuroprotective, anticonvulsant, and anxiolytic-like effects in preclinical models.
- High purity (≥99.0%), suitable for pharmacological studies.
- CAS number 194918-76-8 for unambiguous identification.
- Molecular weight 217.18 g·mol⁻¹; formula C8H11NO6.
- Soluble in water (~2 mg/mL) with sonication and warming.
- Recommended storage: -20°C dry; solutions at -80°C (long term) or -20°C (short term).
- Available in small research quantities, facilitating dose-response and in vivo dosing.
Cayman Chemical LayIlIn Isoform 2 EXrAClul
Source: Recombinant C-terminal human IgG1 Fc-tagged layilin isoform 2 extracellular domain expressed in HEK293 cells • Amino acids: 22-220 • MW: 49.5 kDa
Medchemexpress LLC S961 (acetate) | 99.83% | 4802.12 | 25 MG
S961 acetate is a high-affinity and selective insulin receptor (IR) antagonist. It exhibits IC50s of 0.048 nM for HIR-A, 0.027 nM for HIR-B, and 630 nM for human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay. It also shows high-affinity to Rat IR and Pig IR in PEG-assay.
- High-affinity and selective insulin receptor antagonist
- Exhibits high affinity for human, rat, and pig IR
- Solid, white to off-white appearance
- Soluble in DMSO and water
- Stable under recommended storage conditions