Succinic acid is a dicarboxylic acid which takes the form of succinate in living organisms. Succinate is produced in inflammatory conditions, may be associated with rheumatoid arthritis, and its accumulation is associated with tumorigenesis. It acts through the succinate receptor, SUCNR1 (or GPR91), leading to enhanced IL-1β production. Provided as 10 mg of dry powder. These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter, PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.