Acyl Halides
AdipoGen Methyltrioctadecylammonium Br
Chemical. CAS 18262-86-7. Formula C55H114BrN. MW 869.42. Synthetic. Triple chain lipid. Long chain ionophore used in anion exchange for perchlorate-selective membranes. This is as sensing material with selectivity of chloride-selective polymeric membrane electrode. Organic surfactant. Used as alkylammonium cations for the design of layered chemical sensors.
Medchemexpress LLC Tiotropium Bromide | 136310-93-5 | 99.9% | 472.42 | 5 MG
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and the subsequent opening of the ligand-gated ion channel. This compound stops signaling between neurons, leading to muscle relaxation. It is also a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease and can improve symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.
- mAChR antagonist
- Blocks binding of acetylcholine ligand
- Blocks subsequent opening of ligand-gated ion channel
- Long-acting, 24-hour anticholinergic bronchodilator
- Stops signaling between neurons
- Leads to muscle relaxation
- Used in the management of chronic obstructive pulmonary disease (COPD)
- Improves symptoms of COPD complicated by chronic heart failure
Medchemexpress LLC Mepenzolate bromide | 76-90-4 | 99.9% | 420.34 | 100 MG
Mepenzolate bromide is an orally administered muscarinic receptor antagonist with Kis of 0.68 and 2.6 nM for hM2R and hM3R, respectively. It can be used to suppress gastrointestinal hypermotility associated with irritable bowel syndrome. Mepenzolate bromide is also a GPR109A inhibitor.
- Muscarinic receptor antagonist
- GPR109A inhibitor
- Exerts anti-inflammatory effect via a muscarinic receptor-independent mechanism
- Bronchodilatory effect via a muscarinic receptor-dependent mechanism
- Subtype-non-specific muscarinic antagonist
- Beneficial effects in a mouse model of chronic obstructive pulmonary disease (COPD)
Medchemexpress LLC Ipratropium bromide hydrate | 66985-17-9 | 99.9% | 500 MG
Ipratropium bromide hydrate is a muscarinic receptor antagonist that relaxes smooth muscle. It can be used in research for COPD (chronic obstructive pulmonary disease) and asthma.
- Muscarinic receptor antagonist
- IC50s of 2.9 nM for M1, 2 nM for M2, and 1.7 nM for M3 receptors
- Exerts toxic effects via disruption of mitochondrial membrane potential
- Increases infarct size in isolated perfused heart ischaemia/reperfusion experiments with a dose-responsive manner
- Inhibits adult rat cardiac myocyte growth after hypoxia treatment
Medchemexpress LLC Rapacuronium bromide (Org 9487) | 156137-99-4 | 98.0% | 677.80 | 100 MG
Rapacuronium bromide (Org 9487) is a non-depolarizing neuromuscular blocker and an allosteric modulator of muscarinic acetylcholine receptor (mAChR). It is for research use only.
- Non-depolarizing neuromuscular blocker
- Allosteric modulator of muscarinic acetylcholine receptor (mAChR)
- Binds to all muscarinic receptor subtypes with micromolar affinity and slight selectivity towards M2 receptor
- Exhibits complex effects on the kinetics of ACh binding and subsequent receptor activation
Medchemexpress LLC Pinaverium bromide | 53251-94-8 | 99.7% | 591.42 | 5.9 MG
Pinaverium bromide is an L-type calcium channel blocker that selectively targets the gastrointestinal tract. It is effective in relieving pain, diarrhea, and intestinal discomfort, providing therapeutic benefits for patients with Irritable Bowel Syndrome (IBS) without significant adverse effects.
- L-type calcium channel blocker
- Gastrointestinal selectivity
- Symptom relief for pain, diarrhea, and intestinal discomfort
- Therapeutic for Irritable Bowel Syndrome patients
- Favorable safety profile
Medchemexpress LLC Vecuronium bromide | 50700-72-6 | MFCD00867762 | 99.9% | 100 MG
Vecuronium bromide is a non-depolarizing neuromuscular blocking agent. It also functions as a nicotinic acetylcholine receptor (nAChR) inhibitor and a muscle relaxant. This compound can be used for pre-surgical anesthesia and is intended for research use only.
- Non-depolarizing neuromuscular blocking agent
- Inhibits nicotinic acetylcholine receptors (nAChR)
- Acts as a muscle relaxant
- Can be used for pre-surgical anesthesia
- Suitable for research applications only
Medchemexpress LLC Umeclidinium bromide | 869113-09-7 | MFCD18782614 | 508.49 | 1 G
Umeclidinium bromide is a novel mAChR antagonist, demonstrating high affinity for cloned human M1-M5 mAChRs with Ki values ranging from 0.05 to 0.16 nM. It is a potent agent that exhibits slow functional reversibility at cloned human M3 mAChRs and endogenous mAChRs in isolated human bronchus. This compound is suitable for research in various disease areas including neurological, eye or ear disease, cancer, inflammation or immune system disease, neurodegenerative disease, and Parkinson's disease.
- Novel mAChR antagonist
- High affinity for human M1-M5 mAChRs (Ki 0.05-0.16 nM)
- Inhibits human ether-a-go-go-related gene channel tail current with an IC50 of 9.4 μM
- Demonstrates slow functional reversibility at human M3 mAChRs
- Applicable for research in neurological, ocular, oncological, inflammatory, and neurodegenerative conditions
Medchemexpress LLC Cimetropium Bromide | 51598-60-8 | 438.36 | 5 MG
Cimetropium Bromide (DA-3177) is a mAChR antagonist used for the long-term treatment of irritable bowel syndrome.
Medchemexpress LLC Cimetropium Bromide | 51598-60-8 | 438.36 | 10 MM * 1 ML
Cimetropium Bromide (DA-3177) is an mAChR antagonist developed for the long-term treatment of irritable bowel syndrome. This compound is intended for research use only and functions as a competitive antagonist of muscarinic-mediated contractions in isolated colonic preparations.
- Acts as a competitive antagonist of muscarinic-mediated contractions.
- Exhibits potent antimuscarinic effects on longitudinal muscle preparations.
- Effectively inhibits large bowel motility in vivo.
- Suitable for research applications related to irritable bowel syndrome.
Medchemexpress LLC Rapacuronium bromide (Org 9487) | 156137-99-4 | 98.0% | 677.80 | 25 MG
Rapacuronium bromide (Org 9487) is a non-depolarizing neuromuscular blocker and an allosteric modulator of muscarinic acetylcholine receptor (mAChR). It is for research use only and not sold to patients.
- Non-depolarizing neuromuscular blocker
- Allosteric modulator of muscarinic acetylcholine receptor (mAChR)
Medchemexpress LLC Oleyl bromide ((Z)-1-Bromooctadec-9-ene) | 6110-53-8 | 98.4% | 331.37 | 500 MG
Oleyl bromide ((Z)-1-Bromooctadec-9-ene) is a hydrophobic compound that can carry out ring-opening reactions through a process called "encapsulation." It can also be used as the starting material in the synthesis of oleylphosphonates.
- Hydrophobic compound
- Used in ring-opening reactions
- Starting material for the synthesis of oleylphosphonates
- Appears as a liquid
- Colorless to light yellow in color
Medchemexpress LLC N4-Benzoyl-2'-deoxycytidine | 4836-13-9 | 97.0% | 331.33 | 5 G
N4-Benzoyl-2'-deoxycytidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Medchemexpress LLC N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine | 64325-78-6 | 98.0% | 657.71 | 10 G
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine can be used as an intermediate. It is for research use only and not sold to patients. The product appears as a white to off-white solid.
- Used as an intermediate.
- Solid appearance.
- White to off-white color.
- Available for research purposes.