Benzenoids
Apexbio Technology LLC EZ Cap Mouse IL-36γ mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Mouse IL-36 mRNA encodes cytokine interleukin-36 (IL-36)Gamma primarily involved in inflammatory responses and immune regulation IL-36 acts through binding to the IL-36 receptor activating downstream signaling pathways like NF- B and MAPK promoting the release of inflammatory cytokines and activation of immune cells IL-36 is involved in multiple inflammatory disorders including psoriasis inflammatory bowel diseases and rheumatoid arthritis IL-36 may have pro-inflammatory functions in the pathological processes of these diseases making it a potential therapeutic target EZ Cap Mouse IL-36 mRNA (m1 HA tag) is supplied at 1 mg/mL It expresses mouse IL-36 cytokine fused with an HA tag facilitating subsequent detection With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
BIOHIPPO h/m ACSL4-sh-RFP/Luc
h/m ACSL4-sh-RFP/Luc shRNA lentiviral vector expressing RFP/Luc with selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated h/m ACSL4 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse acyl-CoA synthetase long chain family member 4 (ACSL4) The shRNA has been validated to meet or exceed 70% knockdown of ACSL4 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC M-MLV Reverse transcriptase | 9068-38-6 | 5 KU
M-MLV Reverse transcriptase is a colorless to light yellow liquid with an activity of 200 U/μL. One unit is defined as the amount of enzyme required to incorporate 1 nmol of dTTP into an acid-insoluble fraction using poly(rA)•oligo(dT) as the template-primer under 37 °C for 10 min.
- Source: E.coli
- Store at -20°C for 2 years
- For research use only
Medchemexpress LLC Recombinant human apolipoprotein M (His-tag) | 100 UG
Recombinant human apolipoprotein M (APOM) is a His-tagged protein expressed in HEK293 mammalian cells and supplied as a lyophilized powder formulated in PBS (pH 7.4). It is intended for research applications including biochemical and binding assays, and is characterized by low endotoxin levels and defined molecular weight.
Medchemexpress LLC Metalaxyl-M | 70630-17-0 | 98.1% | 10 MM * 1 ML
Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase. It exhibits fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. It can also be utilized to induce inflammation in hepatocytes, regulate tryptophan metabolism, and for ecotoxicology studies.
- Orally active
- Selective inhibitor of fungal RNA polymerase
- Exhibits fungicidal activity
- Interferes with fungal ribosomal RNA synthesis
- Induces inflammation in hepatocytes
- Regulates tryptophan metabolism
- Used for ecotoxicology studies
Medchemexpress LLC M-PEG2-acid | 149577-05-9 | 25 G
m-PEG2-acid is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These molecules function by harnessing the intracellular ubiquitin-proteeasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Consists of two distinct ligands connected by a linker
- Targets an E3 ubiquitin ligase
- Targets a specific protein
- Harnesses the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC Rspo2/r-spondin-2 protein, mouse (HEK293, Fc) | 92.0% | 100 UG
Recombinant mouse R-spondin-2 Fc-tagged protein produced in HEK293 cells for research on Wnt/β-catenin signaling. The Fc fusion enhances stability and facilitates detection or affinity purification. Supplied as a filtered PBS solution, formulated for storage at low temperature.
Selleck Chemical LLC Pifithrin-μ S2930-50mg
Pifithrin- (NSC 303580 PFT 2-Phenylethynesulfonamide) is a specific p53 inhibitor by reducing its affinity to Bcl-xL and Bcl-2 and also inhibits HSP70 function and autophagy
BIOHIPPO h/m KLF5-sh-GFP-Puro
h/m KLF5-sh-GFP-Puro shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m KLF5 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse KLF transcription factor 5 (KLF5) The shRNA has been validated to meet or exceed 70% knockdown of KLF5 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC Interleukin-21 (mouse), recombinant, His-tagged | >95.0% | 10UG
Animal-Free IL-21 Protein, Mouse (His) is a recombinant murine interleukin-21 produced in E. coli and supplied as a His-tagged, lyophilized protein for research applications in immunology and cytokine signaling. It offers low endotoxin and high specific activity for reliable bioassays.
- Recombinant mouse IL-21 covering residues H18-S146.
- His-tagged for easy detection and purification.
- Expressed in E. coli; non-glycosylated form.
- Purity >95% by reducing SDS-PAGE.
- Endotoxin <0.1 EU per μg (LAL).
- High biological activity: specific activity >1.6x10^5 IU/mg; ED50 <6 ng/mL.
- Lyophilized from PBS with trehalose for stability.
- Store at -20°C; reconstitute and aliquot to avoid freeze-thaw.
Ambeed 3 4Amino2methylpyrimidin5yl m
3-((4-Amino-2-methylpyrimidin-5-yl)methyl)-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride, 59-43-8, 98%
Medchemexpress LLC (2,4,6-trimethyl-phenoxy)-acetic acid | 13333-81-8 | MFCD00224887 | 99.5% | 194.23 g/mol | C11H14O3 | 1 G
(2,4,6-Trimethyl-phenoxy)-acetic acid is a small-molecule herbicide research reagent provided as a powder for laboratory use. It is suitable for biochemical screening, synthesis, and herbicide development studies, and is supplied with analytical and safety documentation for quality control and safe handling.
- High purity (99.5%).
- Powder form, convenient for synthesis and assay preparation.
- Available in multiple laboratory sizes, including 1 G.
- Molecular formula C11H14O3; molecular weight 194.23 g/mol.
- CAS 13333-81-8 for unambiguous identification.
- Supplied with data sheet, COA, and SDS for quality and safety documentation.
- Store powder at -20°C for long-term stability; follow SDS for solvent storage.
Sigma Aldrich Fine Chemicals Biosciences 4-Chloro-3-methylphenol 99% | 59-50-7 | MFCD00002323 | 5G
4-Chloro-3-methylphenol 99% | Purity: 99% | Mol Wt: 142.58 | 59-50-7 | MFCD00002323 | 5G
Medchemexpress LLC Periostin Protein M 20ug
Periostin protein is a multifunctional molecule that plays a key role in cellular processes by inducing cell attachment and spreading emphasizing its importance in cell adhesion dynamics Furthermore Periostin contributes to the structural integrity of connective tissue by enhancing the binding of BMP1 to the fibronectin matrix and promoting subsequent proteolytic activation of lysyl oxidase LOX Periostin Protein Mouse (HEK293 His) is the recombinant mouse-derived Periostin protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Recombinant human colony stimulating factor 1 (macrophage) | 81627-83-0 | >95.0% | 50UG
Recombinant human macrophage colony-stimulating factor (M-CSF/CSF-1) produced in HEK293 cells and supplied as a tag-free, lyophilized protein for research use. It promotes monocyte-macrophage proliferation and differentiation and is used in immunology, oncology, hematopoiesis, and bone biology studies.
- Expressed in HEK293 cells, preserving eukaryotic glycosylation.
- Tag free for applications requiring native sequence.
- Purity greater than 95% by reducing SDS-PAGE.
- Apparent molecular weight ~23-28 kDa under reducing conditions.
- Lyophilized formulation for long-term storage; reconstitute per instructions.
- Biological activity ED50 approximately 0.4-3.0 ng/mL in cell proliferation assays.
- Suitable for macrophage proliferation, differentiation, polarization, and osteoclast studies.