RORγt inverse agonist 13 is a potent, orally active, and selective inverse agonist of the retinoic acid-related orphan receptor γt (RORγt), characterized for preclinical research use. The compound has been profiled for potency, purity, solubility, and storage stability to support in vitro and in vivo studies.
- Potent RORγt inverse agonist with an IC50 of 63.8 nM.
- Orally active and selective for RORγt.
- High purity (~98.1%) suitable for research applications.
- Supplied as a white to off-white solid for convenient handling.
- Highly soluble in DMSO (100 mg/mL) for in vitro assays.
- Formulation demonstrated ≥2.5 mg/mL in 10% DMSO/90% corn oil for in vivo dosing.
- Stable as a powder at -20°C for long-term storage.
- Intended for research use only; not for human therapeutic use.