Benzenoids
Selleck Chemical LLC Ro 61-8048
Ro 61-8048 is a high-affinity kynurenine 3-hydroxylase (KMO) inhibitor with IC50 and Ki of 37 nM and 4 8 nM respectively
![Medchemexpress LLC 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]meth | 1093108-50-9 | 99.4% | 501.50 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000436764-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]meth | 1093108-50-9 | 99.4% | 501.50 | 1 MG
BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). It has IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. This compound shows potential for the treatment of poorly controlled asthma.
- Highly specific and potent antagonist of DP2/CRTH2
- Potential for treating poorly controlled asthma
- Exhibits low nM potency against human or mouse CRTH2 in transfected cells
- Significantly inhibits AHR in mice
- Effectively blocks edema formation and reduces inflammatory infiltrate and skin pathology in drug vehicle-treated animals
Selleck Chemical LLC CPI-637
CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor with IC50 values of 0 03 M and 0 051 M for CBP and EP300 respectively in TR-FRET assay It is highly selective against other bromodomains displaying substantial biochemical activity only against BRD9
Medchemexpress LLC V-9302 hydrochloride | 2416138-42-4 | 99.10% | 575.14 | 100 MG
V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. It selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) but not ASCT1. It inhibits ASCT2-mediated glutamine uptake (IC50=9.6 μM) in HEK-293 cells.
- Competitive antagonist of transmembrane glutamine flux.
- Selectively targets amino acid transporter ASCT2 (SLC1A5).
- Potently inhibits ASCT2-mediated glutamine uptake.
- Attenuates cancer cell growth and proliferation.
- Increases cell death and oxidative stress.
- Prevents tumor growth in xenograft models.
Chem-Impex International, Inc. Bis(triphenylphosphine) palladiuml(II) dichloride | 13965-03-2 | MFCD00009593 | 1G
Bis(triphenylphosphine) palladiuml(II) dichloride, 13965-03-2, MFCD00009593, 1G
Selleck Chemical LLC Ro 61-8048
Ro 61-8048 is a high-affinity kynurenine 3-hydroxylase (KMO) inhibitor with IC50 and Ki of 37 nM and 4 8 nM respectively
Apexbio Technology LLC Mecarbinate 15574-49-9 10mg
Mecarbinate (CAS 15574-49-9) is a small-molecule inhibitor targeting hepatitis C virus (HCV) replication It is designed to inhibit viral replication thereby interfering with essential HCV biological processes Mecarbinate exerts its biological activity primarily through disruption of viral RNA replication potentially by inhibiting viral RNA polymerase or host factors necessary for genome replication In in vitro assays Mecarbinate demonstrates inhibition of HCV RNA replication efficiency with reported IC50 values varying according to experimental context and assay specifics Based on these pharmacological properties Mecarbinate holds research potential in studying viral infection mechanisms and aiding antiviral therapy screening
Medchemexpress LLC 3,3-Difluoropyrrolidine hydrochloride | 163457-23-6 | 143.56 | 25 G
3,3-Difluoropyrrolidine hydrochloride is a biochemical reagent suitable for life science related research. It can be utilized as a biological material or an organic compound.
- Solid appearance
- White to off-white color
- Purity of 99.5%
- Molecular weight of 143.56
- Chemical formula C4H8ClF2N
- CAS number 163457-23-6
Apexbio Technology LLC Deoxyarbutin 53936-56-4 50mg
Deoxyarbutin (CAS 53936-56-4) is a small molecule that acts as a reversible inhibitor of tyrosinase a key enzyme involved in melanin biosynthesis By targeting tyrosinase Deoxyarbutin effectively suppresses enzymatic activity exhibiting an IC50 value of 50 nM in inhibition assays This compound is widely utilized in biomedical research to study melanogenesis explore regulatory mechanisms of skin pigmentation and evaluate potential therapeutic approaches for pigmentary disorders
eMolecules AstaTech / 5-BROMO-2-ETHOXYBENZAMIDE / 0.1g / 696739802 / A12625 / 95.000 / 54924-78-6 / MFCD07551819 / 244.088 / C9H10BrNO2
AstaTech / 5-BROMO-2-ETHOXYBENZAMIDE / 0.1g / 696739802 / A12625 / 95.000 / 54924-78-6 / MFCD07551819 / 244.088 / C9H10BrNO2
![eMolecules Medchem Express / UNC2541 / 5mg / 475641619 / HY-125510 / / 1612782-86-1 / [null] / 471.581 / C24H34FN7O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502457654.PNG-250.jpg)
eMolecules Medchem Express / UNC2541 / 5mg / 475641619 / HY-125510 / / 1612782-86-1 / [null] / 471.581 / C24H34FN7O2
Medchem Express / UNC2541 / 5mg / 475641619 / HY-125510 / / 1612782-86-1 / [null] / 471.581 / C24H34FN7O2