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Organic compounds with acidic properties, and will commonly have carboxylic acids or similar functional groups in their structure. Derived compounds are also included.
GC7 (N1-guanyl-1 7-diaminoheptane) Sulfate is an inhibitor of deoxyhypusine synthase (DHPS) GC7 inhibits Neuroblastoma (NB) cell proliferation in a dose-dependent manner through induction of the cell cycle inhibitor p21 and reduction of total and phosphorylated Rb proteins
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Vindesine sulfate a vinca alkaloid derived from Catharanthus roseus is a potent inhibitor of mitosis with antineoplastic activities Vindesine binds to the microtubular proteins of the mitotic spindle leading to crystallization of the microtubule and mitotic arrest or cell death
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Copper(II) sulfate is an inorganic compound that serves as a source of copper ions. It can form coordination compounds when copper ions coordinate with ligands. This compound is utilized for various enzymatic studies and in material synthesis.
Serves as a source of copper ions
Forms coordination compounds
Utilized for various enzymatic studies
Used in material synthesis
Synthesizes anionic copper sulfate aggregates and chains for magnetic research
Employed as a copper supplement in animal nutrition
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Colistin Sulfate (1264-72-8) is a cyclic antimicrobial peptide targeting the outer membrane of Gram-negative bacteria It is designed to interact electrostatically with negatively charged lipopolysaccharides thereby disrupting membrane integrity and permeability Colistin Sulfate exerts its biological activity primarily through disruption of the bacterial outer membrane In bacterial inhibition assays Colistin Sulfate demonstrates inhibitory activity with IC50 values typically ranging from 0 5 5 g/mL depending on the bacterial strain and experimental conditions Based on these pharmacological properties Colistin Sulfate holds research potential in antimicrobial applications particularly against multidrug-resistant Gram-negative organisms and as a selective agent in bacterial cell culture protocols
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Framycetin sulfate is an aminoglycoside antibiotic that acts as a potent inhibitor of RNase P cleavage activity. It competes for specific divalent metal ion binding sites in RNase P RNA and also inhibits hammerhead ribozyme. This compound is a 5″-azido neomycin B precursor and binds to the Drosha site in miR-525. It is used in the treatment of hepatic encephalopathy and infections caused by enteropathogenic E. coli.
Potent RNase P cleavage activity inhibitor
Inhibits hammerhead ribozyme
Binds to the Drosha site in miR-525
Effective against hepatic encephalopathy and enteropathogenic E. coli infections
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Dihydralazine sulphate (Nepresol Depressan 1 4-Dihydrazinophthalazine Hydralazine) is a dihydralazine-l 4-phthalazine derivative and used as an antihypertensive drug
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NVP-CGM097 sulfate is a potent and selective MDM2 inhibitor, demonstrating an IC50 of 1.7±0.1 nM for hMDM2. It is more potent than Nutlin-3a and effectively reactivates the p53 pathway in MDM2-amplified tumor models, selectively inhibiting the proliferation of cells expressing wild-type p53.
Binds to human MDM2 with high selectivity over MDM4.
More potent than Nutlin-3a.
Inhibits proliferation of cells expressing wild-type p53.
Redistributes wild-type p53 into the cell nucleus.
Reactivates p53 pathway in MDM2-amplified SJSA-1 human tumor models.
Inhibits SJSA-1 tumor growth in rats.
Well absorbed after oral dosing.
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Dopamine 3-O-sulfate is a compound primarily found in plasma. It serves as a valuable biomarker for characterizing aromatic amino acid decarboxylase (AADC) deficiency. It is intended for research use only.
Exists primarily in plasma
Used as a biomarker for aromatic amino acid decarboxylase (AADC) deficiency
Human endogenous metabolite
For research use only
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Penbutolol sulfate, also known as (-)-Terbuclomine, is a potent antagonist for both β-adrenoceptor and 5-HT receptors. It has demonstrated Ki values of 11.6 nM and 11.9 nM for 5-HT in rat cornu ammonis 1 (CA1) and human CA3, respectively. This product is intended strictly for research purposes.
Acts as a potent antagonist for β-adrenoceptor and 5-HT receptors.
Exhibits specific Ki values for 5-HT in CA1 and CA3.
Suitable for various research applications.
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