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Organic compounds with acidic properties, and will commonly have carboxylic acids or similar functional groups in their structure. Derived compounds are also included.
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Ceftolozane sulfate is an antipseudomonal cephalosporin that binds to *P. aeruginosa* essential PBPs (1b, 1c, 2 and 3) with high affinity, inhibiting cell wall synthesis. It is effective against *P. aeruginosa* and Enterobacteriaceae.
Inhibits *P. aeruginosa* PAO1 with an MIC of 0.5 μg/mL
Effective against AmpC-derepressed *P. aeruginosa*
Exhibits antipseudomonal activity against carbapenem-resistant and multi-drug resistant isolates
Reduces ESBL-producing Enterobacteriaceae in vivo
Reduces bacterial load and improves pulmonary inflammatory response in *P. aeruginosa* pneumonia models
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Phenoxymethylpenicillin also known as penicillin V is an antibiotic useful for the treatment of a number of bacterial infections It acts by inhibiting the biosynthesis of cell-wall peptidoglycan
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D-( )-Galacturonic acid monohydrate (D-Galacturonic acid hydrate d-GalA D-galUA) is an endogenous metabolite that can be used in engineering Saccharomyces cerevisiae
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Vinblastine sulfate inhibits microtubule formation and suppresses nAChR activity with IC50 of 8 9 M in a cell-free assay used to treat certain kinds of cancer Vinblastine sulfate induces autophagy and apoptosis
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Vincristine sulfate is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 M in a cell-free assay Vincristine sulfate induces apoptosis
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Aminoguanidine hydrochloride (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. It exhibits a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin and possesses antioxidant properties. It can be utilized in diabetic nephropathy research.
Inhibitor of diamine oxidase and nitric oxide synthase.
Exhibits antioxidant properties.
Has a dose-dependent inhibitory effect on Doxorubicin-induced apoptosis.
Applicable in diabetic nephropathy research.
Can reduce DOX-induced DNA damage and apoptosis in A549 cells.
Can induce ERK activation in AR42J cells and promote cell proliferation.
Protects mice from CCl4-induced hepatotoxicity.
Protective against cyclophosphamide (CP)-induced oxidative stress and kidney damage in rats.
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Used to eliminate inhibition of enzyme catalyzed reactions due to the trace presence of heavy metals.A metal chelating agent commonly used in tissue culture media and biological buffers.Specifications:Ultra Pure GradeChloride: <0.005%Iron: <0.001%Heavy metals (as Pb): <0.001%Appearance: LiquidHS Code : 29224985Melting Point: 255-280 °CPH Value: pH (5%, water, 250º°C): 4.0-5.0
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The Triethanolamine (TEA) Buffer is bifunctional solution that exhibits properties of both alcohols and amines. It is a zwitterionic buffer and can be used as a protein purification reagent in the pH range of 7-8.5 as well as a stationary phase for liquid chromatography. This buffer functions as neutralizing and emulsifying agent, allowing it to neutralize fatty acids and enhance the solubility of oils and other components that are not fully water-soluble.
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Aminoguanidine hydrochloride (CAS 1937-19-5) is a small molecule inhibitor targeting diamine oxidase and nitric oxide synthase It has been shown to attenuate doxorubicin-induced apoptosis in a dose-dependent manner in experimental models In addition to its enzyme inhibitory activities aminoguanidine hydrochloride exhibits antioxidant properties These characteristics make it a widely used tool in research focused on the pathophysiology of diabetic nephropathy and related oxidative stress-mediated conditions
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