Organoheterocyclic compounds
4,6-Dimethylpyrimidine 98.0+%, TCI America™
CAS: 1558-17-4 Molecular Formula: C6H8N2 Molecular Weight (g/mol): 108.14 MDL Number: MFCD00006116 InChI Key: LSBIUXKNVUBKRI-UHFFFAOYSA-N Synonym: 4,6-dimethyl-pyrimidine,pyrimidine, 4,6-dimethyl,unii-95n99d3vhb,pyrimidine, 4,6-dimethyl-6ci,7ci,8ci,9ci,dimethylpyrimidinetech,zlchem 778,pubchem21498,4,6-dimethyl-pyrimidin,4,6-dimethyl-pyrmidine,acmc-1bwo9 PubChem CID: 15257 IUPAC Name: 4,6-dimethylpyrimidine SMILES: CC1=CC(C)=NC=N1
2,6-Diiodopyridine 97.0+%, TCI America™
CAS: 53710-17-1 Molecular Formula: C5H3I2N Molecular Weight (g/mol): 330.895 MDL Number: MFCD07366728 InChI Key: IHBAEQUKKOAEES-UHFFFAOYSA-N PubChem CID: 11427514 IUPAC Name: 2,6-diiodopyridine SMILES: C1=CC(=NC(=C1)I)I
3-Aminoquinoline 99.0+%, TCI America™
CAS: 580-17-6 Molecular Formula: C9H8N2 Molecular Weight (g/mol): 144.177 MDL Number: MFCD00006772 InChI Key: SVNCRRZKBNSMIV-UHFFFAOYSA-N Synonym: 3-aminoquinoline,3-quinolinamine,3-quinolylamine,3-quinolineamine,quinoline, 3-amino,quinolin-3-ylamine,3-amino quinoline,unii-98ovl5k3r4,quinolin-3-yl-amine,ccris 1678 PubChem CID: 11375 IUPAC Name: quinolin-3-amine SMILES: C1=CC=C2C(=C1)C=C(C=N2)N
1-Hexyl-3-methylimidazolium Chloride 98.0+%, TCI America™
CAS: 171058-17-6 Molecular Formula: C10H19N2 Molecular Weight (g/mol): 167.28 MDL Number: MFCD03093289 InChI Key: RVEJOWGVUQQIIZ-UHFFFAOYSA-N Synonym: 1-hexyl-3-methylimidazolium chloride,hmimcl,1-hexyl-3-methyl-1h-imidazol-3-ium chloride,1-hexyl-3-methylimidazol-3-ium chloride,hmim cl,acmc-209e2c,dsstox_cid_27924,dsstox_rid_82677,dsstox_gsid_47948,ksc491c7f PubChem CID: 2734163 ChEBI: CHEBI:61340 IUPAC Name: 3-hexyl-1-methyl-1H-imidazol-3-ium SMILES: CCCCCC[N+]1=CN(C)C=C1
Furfuryl Acetate 97.0+%, TCI America™
CAS: 623-17-6 Molecular Formula: C7H8O3 Molecular Weight (g/mol): 140.138 MDL Number: MFCD00003251 InChI Key: CKOYRRWBOKMNRG-UHFFFAOYSA-N Synonym: furfuryl acetate,2-furanmethanol, acetate,2-furanmethanol acetate,2-acetoxymethylfuran,furfuryl alcohol, acetate,acetic acid furfurylester,acetic acid furfuryl ester,2-furanmethyl acetate,2-furfuryl acetate,2-furylmethyl acetate PubChem CID: 12170 IUPAC Name: furan-2-ylmethyl acetate SMILES: CC(=O)OCC1=CC=CO1
6-Amino-2-benzoxazolinone 97.0+%, TCI America™
CAS: 22876-17-1 Molecular Formula: C7H6N2O2 Molecular Weight (g/mol): 150.137 MDL Number: MFCD00463899 InChI Key: STLPJYGZOIEDAJ-UHFFFAOYSA-N Synonym: 6-aminobenzo d oxazol-2 3h-one,6-amino-1,3-benzoxazol-2 3h-one,2 3h-benzoxazolone, 6-amino,6-amino-2-3h benzoxazolone,6-amino-3h-benzooxazol-2-one,6-amino-2,3-dihydro-1,3-benzoxazol-2-one,6-amino-2-benzoxazolone,6-amino-2-benzoxazolinone,6-amino-3-hydrobenzoxazol-2-one,6-amino-2-hydroxybenzoxazole PubChem CID: 826989 IUPAC Name: 6-amino-3H-1,3-benzoxazol-2-one SMILES: C1=CC2=C(C=C1N)OC(=O)N2
3,6-Dichloro-2-pyridinecarboxylic Acid 98.0+%, TCI America™
CAS: 1702-17-6 Molecular Formula: C6H3Cl2NO2 Molecular Weight (g/mol): 192.00 MDL Number: MFCD00078655 InChI Key: HUBANNPOLNYSAD-UHFFFAOYSA-N Synonym: clopyralid,3,6-dichloropicolinic acid,3,6-dichloro-2-pyridinecarboxylic acid,lontrel,2-pyridinecarboxylic acid, 3,6-dichloro,clopyralide,benzalox,cirtoxin,matrigon,transline PubChem CID: 15553 ChEBI: CHEBI:62961 IUPAC Name: 3,6-dichloropyridine-2-carboxylic acid SMILES: OC(=O)C1=NC(Cl)=CC=C1Cl
2,4,6-Trivinylboroxin - Pyridine Complex 98.0+%, TCI America™
CAS: 95010-17-6 Molecular Formula: C11H14B3NO3 Molecular Weight (g/mol): 240.667 MDL Number: MFCD03839440 InChI Key: YLHJACXHRQQNQR-UHFFFAOYSA-N Synonym: 2,4,6-trivinyl-1,3,5,2,4,6-trioxatriborinane compound with pyridine 1:1,trivinylboroxin pyridine complex,vinylboronic anhydride pyridine complex,2,4,6-trivinylcyclotriboroxane-pyridine,2,4,6-trivinylcyclotriboroxane pyridine,vinylboronic anhydride pyridine,2,4,6-trivinylcyclotriboroxane pyridine complex,2,4,6-trivinylcyclotriboroxane-pyridine complex,boroxin, triethenyl-, compd. with pyridine 1:1,pyridine; triethenyl-1,3,5,2,4,6-trioxatriborinane PubChem CID: 2734806 IUPAC Name: pyridine;2,4,6-tris(ethenyl)-1,3,5,2,4,6-trioxatriborinane SMILES: B1(OB(OB(O1)C=C)C=C)C=C.C1=CC=NC=C1
Apexbio Technology LLC LGX818 1269440-17-6 5mg
LGX818 (CAS 1269440-17-6) is a selective inhibitor of RAF kinase specifically targeting the B-Raf V600E mutant This mutation causes constitutive activation of B-Raf kinase contributing to cancer progression LGX818 selectively inhibits ERK phosphorylation (EC50 3 nM) and suppresses cell proliferation (EC50 4 nM) in BRAF V600E-expressing A375 melanoma cells displaying minimal activity towards wild-type B-Raf In melanoma xenograft models oral administration of LGX818 significantly reduces MEK phosphorylation leading to tumor regression LGX818 is utilized in cancer research as a tool for studying mutant B-Raf-driven signaling pathways
Medchemexpress LLC Glucosylsphingosine | 52050-17-6 | 5 MG
Glucosylsphingosine (lyso-Gb1) is a deacylated form of glucosylceramide that exhibits neurotoxicity. It also functions as a noncompetitive inhibitor of glucocerebrosidase with a Ki value of 30 μM. This compound shows promise for research related to Krabbe and Gaucher disease.
- Exhibits neurotoxicity.
- Functions as a noncompetitive inhibitor of glucocerebrosidase with a Ki value of 30 μM.
- Shows promise for research of Krabbe and Gaucher disease.
Medchemexpress LLC Glucosylsphingosine | 52050-17-6 | 1 MG
Glucosylsphingosine (lyso-Gb1) is a deacylated form of glucosylceramide exhibiting neurotoxicity. It acts as a noncompetitive inhibitor of glucocerebrosidase with a Ki value of 30 μM. This compound is promising for research into Krabbe and Gaucher diseases.
- Acts as a noncompetitive inhibitor of glucocerebrosidase.
- Promising for research of Krabbe and Gaucher disease.
- Induces LA-N-2 cell shriveling and suppresses neurite outgrowth in vitro.
- Reduces activities of lysosomal enzymes including glucocerebrosidase, sphingomyelinase, and β-galactosidase.
- Causes cell death in MCF7 cells independently of apoptosis, ferroptosis, and necroptosis.
- Activates the cAMP signaling pathway.
- Induces a visceral inflammatory response in mice.
- Accumulates in peripheral tissues and causes hematological symptoms in mice.
Apexbio Technology LLC NSC23766 trihydrochloride 1177865-17-6 25mg
NSC23766 trihydrochloride (CAS 1177865-17-6) is a selective inhibitor of the Rac1 GTPase It functions by binding specifically to guanine nucleotide exchange factors (GEFs) such as Trio and Tiam preventing their interaction with Rac1 and thus inhibiting Rac1 activation NSC23766 demonstrates an IC50 of approximately 50 M It has been used in various cellular models to study Rac1-dependent processes including endothelial barrier integrity and apoptosis regulation By modulating Rac1 activity NSC23766 serves as a tool compound for investigating the role of Rac signaling pathways in cellular apoptosis especially TNF- -induced JNK activation and barrier function dynamics
Medchemexpress LLC Glucosylsphingosine | 52050-17-6 | 500 UG
Glucosylsphingosine (lyso-Gb1) is a deacylated form of glucosylceramide that exhibits neurotoxicity. It acts as a noncompetitive inhibitor of glucocerebrosidase and is relevant for research in Krabbe and Gaucher diseases.
- Deacylated form of glucosylceramide
- Exhibits neurotoxicity
- Noncompetitive inhibitor of glucocerebrosidase
- Used in research for Krabbe and Gaucher diseases
- Suppresses neurite outgrowth
- Reduces activity of lysosomal enzymes
- Induces cell death in MCF7 cells
- Activates cAMP signaling pathway
- Induces visceral inflammatory response in mice
- Causes hematological symptoms and tissue inflammation in mice
Medchemexpress LLC 12-Deoxywithastramonolide | 60124-17-6 | 10 MG
12-Deoxywithastramonolide is a principal bioactive compound found in ashwagandha (W. somnifera). It possesses antioxidant and enzyme inhibitory effects, making it suitable for various biological research applications.
- Naturally occurring compound found in ashwagandha (W. somnifera).
- Exhibits antioxidant properties.
- Possesses enzyme inhibitory capabilities.
Medchemexpress LLC 12-Deoxywithastramonolide | 60124-17-6 | 1 MG
12-Deoxywithastramonolide is a principal bioactive compound from ashwagandha (Withania somnifera), known for its antioxidant and enzyme inhibitory properties. With a molecular weight of 470.60 and formula C28H38O6, it appears as a white to off-white solid, categorized under steroids from plant sources. For research use only, not human therapeutic use. Optimal storage: powder at -20°C (3 years) or 4°C (2 years); in solvent, -80°C (6 months) or -20°C (1 month). Shipping is stable at room temperature for less than two weeks.
- Principal bioactive compound from ashwagandha (W. somnifera)
- Possesses antioxidant and enzyme inhibitory effects
- Molecular weight of 470.60, formula C28H38O6
- White to off-white solid appearance
- Classified under steroids from plant origins
- For research use only
- Powder stable at -20°C (3 years) or 4°C (2 years)
- Solvent stable at -80°C (6 months) or -20°C (1 month)