Organoheterocyclic compounds
Carbazole 97.0+%, TCI America™
CAS: 86-74-8 Molecular Formula: C12H9N Molecular Weight (g/mol): 167.21 MDL Number: MFCD00004960 InChI Key: UJOBWOGCFQCDNV-UHFFFAOYSA-N Synonym: carbazole,dibenzopyrrole,diphenylenimine,9-azafluorene,diphenylenimide,diphenyleneimine,dibenzo b,d pyrrole,usaf ek-600,unii-0p2197hhhn PubChem CID: 6854 ChEBI: CHEBI:27543 IUPAC Name: 9H-carbazole SMILES: N1C2=C(C=CC=C2)C2=C1C=CC=C2
4-Quinolinecarboxylic Acid 98.0+%, TCI America™
CAS: 486-74-8 Molecular Formula: C10H7NO2 Molecular Weight (g/mol): 173.171 MDL Number: MFCD00006782 InChI Key: VQMSRUREDGBWKT-UHFFFAOYSA-N Synonym: 4-quinolinecarboxylic acid,cinchoninic acid,4-carboxyquinoline,cinchonic acid,usaf d-2,quinoline-4-carboxylicacid,4-quinolinecarboxylicacid,cinchoninsaure,pubchem5843,chinolin-4-carbonsaeure PubChem CID: 10243 ChEBI: CHEBI:18311 IUPAC Name: quinoline-4-carboxylic acid SMILES: C1=CC=C2C(=C1)C(=CC=N2)C(=O)O
2-Amino-3,5-dichloropyridine 98.0+%, TCI America™
CAS: 4214-74-8 Molecular Formula: C5H4Cl2N2 Molecular Weight (g/mol): 163.00 MDL Number: MFCD00006313 InChI Key: OCWBGKZFOYMCCN-UHFFFAOYSA-N Synonym: 2-amino-3,5-dichloropyridine,3,5-dichloro-2-pyridinamine,2-pyridinamine, 3,5-dichloro,3,5-dichloro-3-pyridylamine,3,5-dichloro-2-aminopyridine,3,5-dichloro-2-pyridylamine,3,5-dichloropyridin-2-ylamine,pyridine, 2-amino-3,5-dichloro,pubchem13504,acmc-209jnv PubChem CID: 77886 IUPAC Name: 3,5-dichloropyridin-2-amine SMILES: NC1=NC=C(Cl)C=C1Cl
1,8-Cineole 99.0+%, TCI America™
CAS: 470-82-6 Molecular Formula: C10H18O Molecular Weight (g/mol): 154.25 MDL Number: MFCD00167977 InChI Key: WEEGYLXZBRQIMU-UHFFFAOYSA-N Synonym: eucalyptol,cineole,1,8-cineole,1,8-cineol,cajeputol,1,8-epoxy-p-menthane,eucalyptole,zineol,eucapur,terpan PubChem CID: 2758 IUPAC Name: 1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane SMILES: CC12CCC(CC1)C(C)(C)O2
1,8-Cineole 98.0+%, TCI America™
CAS: 470-82-6 Molecular Formula: C10H18O Molecular Weight (g/mol): 154.25 MDL Number: MFCD00167977 InChI Key: WEEGYLXZBRQIMU-UHFFFAOYSA-N Synonym: eucalyptol,cineole,1,8-cineole,1,8-cineol,cajeputol,1,8-epoxy-p-menthane,eucalyptole,zineol,eucapur,terpan PubChem CID: 2758 IUPAC Name: 1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane SMILES: CC12CCC(CC1)C(C)(C)O2
Methyl 2-Bromothiazole-5-carboxylate 95.0+%, TCI America™
CAS: 54045-74-8 Molecular Formula: C5H4BrNO2S Molecular Weight (g/mol): 222.056 MDL Number: MFCD03788565 InChI Key: HNLVIKMXFBRZDF-UHFFFAOYSA-N Synonym: methyl 2-bromothiazole-5-carboxylate,methyl 2-bromo-5-thiazole carboxylate,methyl2-bromothiazole-5-carboxylate,5-thiazolecarboxylic acid, 2-bromo-, methyl ester,2-bromo-thiazole-5-carboxylic acid methyl ester,2-bromothiazole-5-carboxylic acid methyl ester,2-bromo-1,3-thiazole-5-carboxylic acid methyl ester,pubchem17197,acmc-1apjm,ksc494s7p PubChem CID: 2773502 IUPAC Name: methyl 2-bromo-1,3-thiazole-5-carboxylate SMILES: COC(=O)C1=CN=C(S1)Br
2,3,7,8,12,13,17,18-Octaethylporphyrin 95.0+%, TCI America™
CAS: 2683-82-1 Molecular Formula: C36H46N4 Molecular Weight (g/mol): 534.792 MDL Number: MFCD00009627 InChI Key: XFIIGRBIXXECHR-UHFFFAOYSA-N Synonym: octaethylporphine,octaethylporphyrin,2,3,7,8,12,13,17,18-octaethyl-21h,23h-porphine,2,3,7,8,12,13,17,18-octaethylporphyrin,octaethylpophine,21h,23h-porphine, 2,3,7,8,12,13,17,18-octaethyl,octaethylporphyrine,2,3,7,8,12,13,17,18-octaethyl-21h,23h-porphin,acmc-209gte,hciifbhdbocsaf-muzkialcsa-n PubChem CID: 102311 IUPAC Name: 2,3,7,8,12,13,17,18-octaethyl-21,22-dihydroporphyrin SMILES: CCC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)CC)CC)C(=C4CC)CC)C(=C3CC)CC)CC
Apexbio Technology LLC UBP1112 339526-74-8 50mg
UBP1112 is an antagonist targeting type III metabotropic glutamate (mGlu) receptors a subgroup of G protein-coupled receptors involved in synaptic modulation of excitatory neurotransmission within the central nervous system Structurally UBP1112 interacts specifically with these receptors blocking glutamate binding and subsequently altering downstream signal transduction In neuroscience research UBP1112 serves as an investigative tool for examining receptor-mediated neuronal signaling pathways and for studying pathophysiological mechanisms underlying neurodegenerative conditions
Apexbio Technology LLC FAPI-74 2374782-76-8 25mg
FAPI-74 (CAS 2374782-76-8) is a small molecule positron emission tomography (PET) tracer that selectively targets fibroblast activation protein (FAP) a serine protease overexpressed in cancer-associated fibroblasts within the tumor microenvironment By binding to FAP FAPI-74 enables noninvasive imaging of FAP-expressing tissues facilitating tumor detection and characterization This compound is utilized in preclinical and clinical research to investigate tumor biology monitor disease progression and assess the potential of FAP as a diagnostic and therapeutic target in oncology studies
Apexbio Technology LLC Buclizine HCl 129-74-8 50mg
Buclizine hydrochloride (CAS 129-74-8) is a synthetic piperazine derivative classified as an antihistamine and anticholinergic agent It functions by competitively inhibiting histamine H1 receptors thereby reducing histamine-mediated responses and also exhibits antagonistic activity at muscarinic acetylcholine receptors These dual actions have established its use in studies exploring the modulation of allergic reactions motion sickness and the central and peripheral effects of histaminergic and cholinergic pathways Buclizine HCl is utilized in biomedical research to investigate receptor pharmacology and signal transduction mechanisms associated with histaminergic and cholinergic neurotransmission
Apexbio Technology LLC Alectinib Hydrochloride 1256589-74-8 100mg
Alectinib Hydrochloride (CAS 1256589-74-8) is an orally administered selective inhibitor of anaplastic lymphoma kinase (ALK) that acts by competitively binding to the ATP-binding site of the ALK kinase domain thereby disrupting downstream signaling pathways In vitro studies demonstrate potent inhibition of ALK with an IC50 of approximately 1 9 nM and it also effectively targets ALK mutant variants F1174L (IC50 1 nM) and R1275Q (IC50 3 5 nM) Owing to its ability to penetrate the central nervous system alectinib hydrochloride is utilized in cancer research to investigate ALK-dependent tumorigenesis and mechanisms of drug resistance
Apexbio Technology LLC Alectinib Hydrochloride 1256589-74-8 50mg
Alectinib Hydrochloride (CAS 1256589-74-8) is an orally administered selective inhibitor of anaplastic lymphoma kinase (ALK) that acts by competitively binding to the ATP-binding site of the ALK kinase domain thereby disrupting downstream signaling pathways In vitro studies demonstrate potent inhibition of ALK with an IC50 of approximately 1 9 nM and it also effectively targets ALK mutant variants F1174L (IC50 1 nM) and R1275Q (IC50 3 5 nM) Owing to its ability to penetrate the central nervous system alectinib hydrochloride is utilized in cancer research to investigate ALK-dependent tumorigenesis and mechanisms of drug resistance
Apexbio Technology LLC FAPI-74 2374782-76-8 10mg
FAPI-74 (CAS 2374782-76-8) is a small molecule positron emission tomography (PET) tracer that selectively targets fibroblast activation protein (FAP) a serine protease overexpressed in cancer-associated fibroblasts within the tumor microenvironment By binding to FAP FAPI-74 enables noninvasive imaging of FAP-expressing tissues facilitating tumor detection and characterization This compound is utilized in preclinical and clinical research to investigate tumor biology monitor disease progression and assess the potential of FAP as a diagnostic and therapeutic target in oncology studies