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Isosinensetin is a naturally occurring flavonoid research compound used as an inhibitor of HIV-1 protease and protein tyrosine phosphatase 1B (PTP1B), with reported activity against P-glycoprotein. It is provided as a high-purity reagent for biochemical and cell-based studies.
High purity (99.9%) suitable for research applications.
Molecular formula C20H20O7; molecular weight 372.37.
Reported biological activities include PTP1B and HIV-1 protease inhibition and P-gp modulation.
Recommended storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
Supplied as a 10 mg vial for small-scale laboratory research.
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Pentagamavunon-1 (PGV-1) is a synthetic curcumin analog used in preclinical research as a cyclooxygenase (COX) inhibitor and apoptosis-inducing agent. It is employed in cellular and in vivo studies to investigate tumor suppression, reactive oxygen species (ROS) metabolism, and cell-cycle effects, and is provided as a stable solid with guidance for solvent preparation and storage.
Curcumin analog with reported oral activity.
Inhibits COX and modulates ROS metabolic enzymes.
Induces apoptosis and M-phase (prometaphase) cell-cycle arrest.
High purity suitable for research use (~99%).
Soluble in DMSO for in vitro stock preparation.
Stable with recommended low-temperature storage for long-term preservation.
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MRTX-1133 (CAS 2621928-55-8) is a non-covalent alkyne-based inhibitor specifically targeting the KRAS G12D mutant protein It binds KRAS G12D with sub-picomolar affinity occupying the Switch II pocket and forming multiple intermolecular interactions Through these interactions MRTX-1133 disrupts SOS1-mediated guanine nucleotide exchange and prevents the assembly of KRAS-GTP/RAF1 signaling complexes thereby inhibiting downstream KRAS-driven signaling pathways MRTX-1133 is applied in cancer biology research to investigate tumor signaling and therapeutic strategies involving KRAS G12D mutations
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Glycyrrhisoflavone is an active prenylflavonoid that inhibits α-glucosidase, provided as an analytical standard for research and analytical applications. It is supplied with defined purity and molecular characterization useful for assay development and analytical workflows.
High purity of 99.43%.
Provided as a 10 mg analytical standard.
Useful as an α-glucosidase inhibitor in biochemical assays.