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PF-562271 besylate is an ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (Pyk2) used as a research tool in cell-signaling and oncology studies. It exhibits potent biochemical activity (FAK IC50 ≈ 1.5 nM; Pyk2 IC50 ≈ 13-14 nM), is supplied as the besylate salt, and is available at high purity for in vitro and in vivo research.
Potent ATP-competitive, reversible inhibitor of FAK and Pyk2.
Low nanomolar biochemical potency for target kinases.
Provided as a besylate salt for improved stability and handling.
High reported purity suitable for research applications.
Used in cellular and animal model studies of tumor signaling pathways.
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Phytosphingosine (4-Hydroxysphinganine) is a phospholipid that exhibits anti-inflammatory, antibacterial, and anti-cancer properties. It functions as an immune regulator and an activator of GPR120 with an IC50 value of 33.4 μM. This compound is useful for research into inflammatory skin diseases and type II diabetes.
Induces apoptosis
Effective against inflammation
Possesses antibacterial activity
Exhibits anti-cancer activities
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PSB-1115 is a selective A2B adenosine receptor antagonist for pharmacological research. It inhibits TNBS-induced acetylcholine contraction in vitro and antagonizes NECA-induced inhibition of mucociliary clearance in vivo.
Selective A2B adenosine receptor antagonist
Purity 99.0%
Molecular weight 350.35 g/mol
Chemical formula C14H14N4O5S
CAS number 152529-79-8
Solubility: DMSO 100 mg/mL; H2O 10 mg/mL
Storage: -20°C; in solvent -80°C (6 months)
Intended for research use only
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Also available in 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Biotin-aniline is a probe that reacts strongly to RNA and DNA.Biotin-aniline is highly efficient and is used to capture subcellular transcriptomes in living cells with high spatial specificity. Purity 99.08%
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More