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BD-1047 dihydrobromide is a selective functional antagonist of sigma receptors. It attenuates Apomorphine-induced climbing and Phencyclidine-induced head twitches. It is for research use only and not sold to patients.
Selective functional antagonist of sigma receptors.
Attenuates Apomorphine-induced climbing.
Attenuates Phencyclidine-induced head twitches.
Prevents Cutamesine from reducing cell death induced by light exposure in murine photoreceptor-derived 661w cells.
Attenuates Cutamesine from reducing mitochondrial damage and elevated caspase 3/7 activity.
Decreases APO-induced climbing behavior at 10 mg/kg in mice.
Counteracts the antidepressant-like effect induced by co-administration of pramipexole and sertraline.
Reduces the increasing expression of pNR1 and reverses Sig-1 R agonists potentiated NMDA-induced pain behavior and pNR1 immunoreactivity.
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A potent and selective prostaglandin E2 (EP1) antagonist. Displays in vivo analgesic activity in the rat. Does not block PGE1-induced hyperalgesia. Purity: ≥98% (HPLC). Solubility: Soluble in water or DMSO (25mg/ml). Long Term Storage: -20°C.
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