Trans-Anethole is an orally active phenylpropene derivative found in Foeniculum vulgare. It exhibits estrogenic activity at low concentrations and cytotoxicity at high concentrations in tumor cell lines. This compound also possesses anti-aflatoxin, anti-thrombotic, and anti-diabetic activities, and is a significant odor component in plants such as fennel and liquorice.
- Orally active phenylpropene derivative.
- Exhibits estrogenic activity at low concentrations.
- Cytotoxic at high concentrations in tumor cell lines.
- Possesses anti-aflatoxin, anti-thrombotic, and anti-diabetic activities.
- Causes cell death in isolated rat hepatocytes.
- Shows antithrombotic activity in male Swiss mice.
- Normalizes glucose metabolizing enzymes and improves liver/muscle glycogen content in diabetic rats.
- Inhibits pregnancy in adult albino rats.