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2-Amino-5-methylpyrazine is an intermediate chemical compound primarily used in the synthesis of LPAR1 antagonists. This product is intended for research purposes only and not for patient use.
Utilized as an intermediate for LPAR1 antagonist synthesis.
Purity of 99.7%.
Appears as a light brown to yellow solid.
Highly soluble in DMSO.
Store at 4°C, protected from light.
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TUG-770 (CAS 1402601-82-4) is a potent agonist of the free fatty acid receptor 1 (FFA1/GPR40) a G protein-coupled receptor implicated in the enhancement of glucose-stimulated insulin secretion by pancreatic -cells TUG-770 demonstrates high affinity for FFA1 with an EC50 of 6 nM and over 150-fold selectivity compared to FFA4 as well as high selectivity over other receptors and transporters In INS-1E rat -cell lines TUG-770 promotes insulin secretion in the presence of elevated glucose Pharmacokinetic studies in mice indicate favorable oral absorption and bioavailability with dose-dependent reductions in blood glucose during glucose tolerance tests TUG-770 is a valuable tool for investigating FFA1-mediated pathways and glucose homeostasis in metabolic research
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1,1-Bis(methylthio)-2-nitroethylene is an organic nitroethylene reagent used in biochemical and organic chemistry research as a building block or assay reagent. It is supplied as a characterized solid for laboratory use and includes documentation for safe handling and analytical verification.
High purity (99.7%).
Solid, yellow to brown powder.
Storage guidance provided for powder and solutions.
Multiple small pack sizes available for research use.
Analytical documents available: data sheet, COA, SDS, H NMR, and GC.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
LP-261 is a potent, orally active anti-mitotic agent. It demonstrates inhibition of in vitro tubulin polymerization with an EC50 of 3.2 μM. This compound has shown efficacy in inhibiting the growth of human non-small-cell lung tumors (NCI-H522) in vivo, making it a valuable tool for cancer research.
Potent anti-mitotic agent.
Orally active.
Inhibits in vitro tubulin polymerization.
Effective against human non-small-cell lung tumors (NCI-H522) in vivo.
Useful for cancer research applications.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More