Phenylpropanoids and polyketides
Medchemexpress LLC Phosphine, diphenyl-1-pyrenyl- | 110231-30-6 | 95.0% | 386.42 | C28H19P | 50 MG
Diphenyl-1-pyrenylphosphine (DPPP) is a phosphine-based fluorogenic probe used to detect peroxides and lipid peroxidation in biological samples. It exhibits phototriggered aggregation-induced emission/aggregation-caused quenching behavior and is supplied as a solid reagent for research applications.
- Fluorogenic probe that reacts with peroxides to yield a fluorescent product.
- Sensitive detection of lipid peroxidation in cells and tissues.
- Exhibits phototriggered AIE/ACQ transition for enhanced fluorescence control.
- Off-white to light yellow solid, suitable for laboratory handling and storage.
- Store protected from light; stable under recommended cold storage conditions.
Medchemexpress LLC Phosphine, diphenyl-1-pyrenyl- | 110231-30-6 | MFCD00278755 | 95.0% | 386.42 | C28H19P | 5 MG
Diphenyl-1-pyrenylphosphine (DPPP) is a fluorogenic peroxide-reactive probe used to detect hydroperoxides and study photophysical behavior. It exhibits phototriggered aggregation-induced emission (AIE) / aggregation-caused quenching (ACQ) transitions and notable third-order nonlinear optical responses. Typically supplied as a solid in small milligram quantities for research use.
- Fluorogenic probe for peroxide and ROS detection.
- Photophysical behavior: AIE/ACQ transitions and third-order nonlinear optical response.
- Purity 95.0%.
- Molecular weight 386.42 Da.
- Chemical formula C28H19P.
- Supplied as a solid powder in milligram quantities.
Medchemexpress LLC Isodecyl diphenyl phosphate | 29761-21-5 | MFCD00072254 | 99.0% | 390.45 | C22H31O4P | 10mg
Isodecyl diphenyl phosphate (IDPP) is a flame retardant IDPP has an ability to induce DNA damage and exertes S phase cell ratio-reducing effects in A549 cells[1]
Apexbio Technology LLC trans-9-Tetradecenoic acid 50286-30-1 10mg
trans-9-Tetradecenoic acid (CAS 50286-30-1) is a monounsaturated fatty acid comprising a 14-carbon chain with a trans double bond at the ninth carbon It occurs naturally in select plant oils dairy products and as a metabolic intermediate in certain microorganisms By serving as a substrate or modulator within fatty acid metabolic pathways trans-9-Tetradecenoic acid is utilized in biochemical studies to investigate lipid metabolism fatty acid desaturation and associated physiological processes Its presence in biological systems also makes it relevant for research on dietary lipids and their roles in health and disease
Medchemexpress LLC Naringenin chalcone | 73692-50-9 | MFCD00016762 | 25 MG
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. It functions as a metabolite and is known for its anti-allergic and anti-inflammatory properties. This chalcone is also noted for inducing apoptosis and inhibiting the production of MCP-1 and NO, as well as exhibiting anticancer activity against glioblastoma. This product is intended for research use only.
- Intermediate in flavonol biosynthesis
- Induces apoptosis
- Inhibits the production of MCP-1 and NO
- Exhibits anticancer activity against glioblastoma
- Possesses anti-inflammatory properties
- Possesses anti-allergic properties
- Functions as a metabolite
- Intended for research use only
Medchemexpress LLC (±)-Naringenin (Standard) | 67604-48-2 | 98.8% | 272.25 | 25 MG
(±)-Naringenin (Standard) is the analytical standard of (±)-Naringenin. It is a naturally-occurring flavonoid intended for research and analytical applications. It displays a vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes.
- Used as a reference standard in qualitative, quantitative, and methodological research experiments.
- Commonly applied in techniques such as HPLC, GC, and MS.
- Appearance is a solid, white to light yellow.
- Chemical formula is C₁₅H₁₂O₅.
- Classified under flavonoids and phenols.
- Initial source is from other plant families.
![Medchemexpress LLC 3-Pyridinecarboxamide, 6-[4-(1-aminocyclobutyl)phenyl]-5-pheny | 1357158-81-6 | 98.4% | 343.42 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387556-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 3-Pyridinecarboxamide, 6-[4-(1-aminocyclobutyl)phenyl]-5-pheny | 1357158-81-6 | 98.4% | 343.42 | 1 ML
AKT-IN-1 is an allosteric AKT inhibitor with an IC50 of 1.042 μM. It potently inhibits phosphorylation of AKT in cells at both Thr308 and Ser473. In vivo, it causes significant tumor growth inhibition in breast adenocarcinoma xenograft models.
- Allosteric AKT inhibitor.
- Potently inhibits phosphorylation of AKT in cells at both Thr308 and Ser473, with IC50s of 0.422 and 0.322 μM respectively.
- Inhibits the phosphorylation of ribosomal protein S6, a downstream effector of the PI3K-AKT pathway.
- Potently inhibits the phosphorylation of PRAS40.
- In vivo, potently inhibits the phosphorylation of its downstream substrate GSK3β as well as the phosphorylation of AKT (Ser473).
- Causes significant tumor growth inhibition in BT474c breast adenocarcinoma xenograft models when dosed at 200 mg/kg daily.
Medchemexpress LLC Trans-chalcone | 614-47-1 | MFCD00003082 | 98.8% | 208.26 g/mol | C15H12O | 5g
trans-Chalcone isolated from Aronia melanocarpa skin is a biphenolic core structure of flavonoids precursor trans-Chalcone is a potent fatty acid synthase (FAS) and -amylase inhibitor trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7 trans-Chalcone has antifungal and anticancer activity[1][2][3]
Medchemexpress LLC AKT inhibitor VIII | 612847-09-3 | MFCD23843802 | 99.0% | 551.64 g/mol | C34H29N7O | 100 MG
AKT inhibitor VIII is a cell-permeable, reversible allosteric inhibitor of Akt kinases used as a research reagent to probe PI3K/Akt signaling pathways. It is supplied as a light yellow solid for laboratory use.
- Allosteric, reversible Akt inhibitor.
- Isoform-selective activity with greater potency for Akt1 and Akt2.
- Reported IC50 values: Akt1 = 58 nM, Akt2 = 210 nM.
- Molecular formula C34H29N7O; molecular weight 551.64 g/mol.
- High reported purity (~99%).
- Supplied as a light yellow solid with recommended storage for powder at -20°C or 4°C depending on duration.
Medchemexpress LLC (±)-Naringenin | 67604-48-2 | MFCD00006844 | 99.83% | 272.26 | 1 ML
(±)-Naringenin is an orally available anti-inflammatory agent that regulates acute and chronic inflammation, and exhibits antioxidant, neuroprotective, liver-protective, and anti-cancer effects. It promotes vasodilation and protects against experimental colitis by inhibiting Toll-like receptor 4/NF-κB signaling, useful in studies of sepsis, fulminant hepatitis, fibrosis, and cancer. It appears as an off-white to light yellow solid.
- Regulates acute and chronic inflammation.
- Antioxidant, neuroprotective, liver-protective, and anti-cancer effects.
- Promotes vasodilation.
- Protects against experimental colitis.
- Useful in sepsis, hepatitis, fibrosis, and cancer research.
- Orally available.
Medchemexpress LLC (±)-Naringenin (Standard) | 67604-48-2 | MFCD00006844 | 98.8% | 272.25 | 50 MG
(±)-Naringenin (Standard) is an analytical standard of (±)-Naringenin, designed for research and analytical applications. This naturally-occurring flavonoid exhibits a vasorelaxant effect on endothelium-denuded vessels by activating BKCa channels in myocytes. As an analytical standard grade compound, it serves as a reliable reference for various assays.
- Serves as a reference standard for assays.
- Used in qualitative, quantitative, and methodological research experiments.
- Suitable for HPLC, GC, and MS applications.
Medchemexpress LLC (±)-Naringenin (Standard) | 67604-48-2 | 98.8% | 272.25 | 100 MG
(±)-Naringenin (Standard) is the analytical standard of (±)-Naringenin, intended for research and analytical applications. It is a naturally-occurring flavonoid that displays a vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes.
- Analytical standard grade
- Naturally-occurring flavonoid
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- Appearance: solid, white to light yellow
- Structure classification: flavonoids, phenols
- Initial source: plants other families
- Displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes.
