Phenylpropanoids and polyketides
Medchemexpress LLC Naringenin chalcone | 73692-50-9 | 1 MG
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis.
Medchemexpress LLC 4'-Hydroxychalcone | 2657-25-2 | 1 ML
4'-Hydroxychalcone is a chalcone isolated from licorice root with hepatoprotective activity. It inhibits TNFa-induced NF-κB activation via proteasome inhibition. It also induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria.
- Isolated from licorice root
- Exhibits hepatoprotective activity
- Inhibits TNFa-induced NF-κB activation through proteasome inhibition
- Induces rapid potassium release from mitochondrial vesicles
- Causes deterioration of respiratory control and oxidative phosphorylation
- Affects cancer cell viability
TARGETMOL CHEMICALS INC Naringenin chalcone 10MG
Also available in 1 mg, 2 mg, 5 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Naringenin chalcone is a natural product isolated from the stem of the plant Machaerium isadelphum (Fabaceae).Naringenin chalcone has anti-inflammatory activity. Purity 98.11%
Medchemexpress LLC (±)-Naringenin | 67604-48-2 | MFCD00870553 | 99.8% | 272.26 | 500 MG
(±)-Naringenin | 67604-48-2 | MFCD00870553 | 99.8% | 272.26 | 500 MG
Selleck Chemical LLC Chalcone
Chalcone (benzylideneacetophenone phenyl styryl ketone benzalacetophenone -phenylacrylophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds which are known collectively as chalcones with antibacterial antifungal antitumor and anti-inflammatory properties
Medchemexpress LLC (E)-Naringenin chalcone | 25515-46-2 | 25 MG
(E)-Naringenin chalcone is an orally active anti-allergic agent that exhibits antioxidant and anti-inflammatory properties. It can enhance adipocyte functions and inhibits the release of histamine from rat peritoneal mast cells.
- Anti-allergic agent: orally active and inhibits histamine release from rat peritoneal mast cells.
- Antioxidant activity: possesses antioxidant properties.
- Anti-inflammatory activity: demonstrates anti-inflammatory effects.
- Adipocyte function improvement: can improve the functions of adipocytes.
- PPARγ stimulation: stimulates the activity of PPARγ in NIH-3T3 cells.
- Inhibition of inflammatory mediators: inhibits the production of TNF-alpha, MCP-1, and nitric oxide (NO) by LPS-stimulated RAW 264 macrophages.
- Suppresses allergic asthma: inhibits the type-2 function of CD4 T cells in allergic airway inflammatory mice.
Apexbio Technology LLC Naringenin 480-41-1 100mg
Naringenin (CAS 480-41-1) is a small-molecule inhibitor designed to modulate inflammatory and antiviral pathways thereby regulating cellular inflammatory responses and viral replication Naringenin exerts its biological activity primarily through inhibition of the NF- B pathway resulting in reduced inflammatory cytokine production Additionally it demonstrates antioxidative properties by scavenging reactive oxygen species (ROS) In in vitro studies naringenin exhibits inhibition of dengue virus replication with reported IC50 values ranging from approximately 52 64 M to 143 M depending on experimental conditions and viral strains Based on these pharmacological properties naringenin holds research potential in inflammation oxidative stress-related cellular models and dengue virus infection studies
Medchemexpress LLC Trans-chalcone | 614-47-1 | MFCD00003082 | 98.8% | 208.26 | C15H12O | 100g
trans-Chalcone isolated from Aronia melanocarpa skin is a biphenolic core structure of flavonoids precursor trans-Chalcone is a potent fatty acid synthase (FAS) and -amylase inhibitor trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7 trans-Chalcone has antifungal and anticancer activity[1][2][3]
Medchemexpress LLC 4'-Methoxychalcone | 959-23-9 | 99.8% | 1 ML
4'-Methoxychalcone regulates adipocyte differentiation by activating PPARγ. It also modulates the expression and secretion of various adipokines in adipose tissue, which are involved in insulin sensitivity. The compound has demonstrated antiproliferative activity against human A2780, CAL-51, HCT-116, HT-29, and MSTO-211H cells, and cytotoxicity against DLD-1, FHC, HCT-116, and L929 cells.
- Regulates adipocyte differentiation by activating PPARγ.
- Modulates adipokine expression and secretion for insulin sensitivity.
- Demonstrates antiproliferative activity against human A2780, CAL-51, HCT-116, HT-29, and MSTO-211H cells.
- Exhibits cytotoxicity against DLD-1, FHC, HCT-116, and L929 cells.
Medchemexpress LLC Pinostrobin chalcone | 18956-15-5 | 99.9% | 270.28 g/mol | C16H14O4 | 10 MG
Pinostrobin chalcone is a naturally occurring chalcone derivative supplied as a high-purity research standard for in vitro biological and analytical studies. It has reported cytotoxic activity against MDA-MB-231 and HT-29 cancer cell lines (IC50 = 20.42 ± 2.23 μg/mL and 22.51 ± 0.42 μg/mL). The compound is provided as a solid and should be stored sealed at 4°C, protected from moisture and light.
- High purity (99.94%).
- Molecular weight 270.28 g/mol.
- Chemical formula C16H14O4.
- CAS number 18956-15-5.
- Suitable for in vitro cytotoxicity and analytical assays.
- Provided in a 10 MG package for laboratory use.
- Store at 4°C, sealed, away from moisture and light.
Medchemexpress LLC Pinocembrin chalcone | 4197-97-1 | 1 MG
Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound derived from *Helichrysum Trilineatum*. It facilitates AMP-activated protein kinase (AMPK) activation, improves glucose tolerance, increases muscle fatty acid oxidation (FAO), and reduces fat accumulation in the liver and skeletal muscles of high-fat diet-induced (HFD) diabetic mice. It is suitable for research on gastric ulcers and diabetes.
- Antibacterial properties
- Activates AMP-activated protein kinase (AMPK)
- Improves glucose tolerance
- Increases muscle fatty acid oxidation
- Reduces fat accumulation in liver and skeletal muscles
- Supports research on gastric ulcers and diabetes
Medchemexpress LLC (E)-naringenin chalcone | 25515-46-2 | MFCD00016762 | 98.9% | 272.26 g/mol | C15H12O5 | 10 MG
(E)-Naringenin chalcone is a flavonoid-derived chalcone supplied for research use. It is described as an orally active anti-allergic agent with reported antioxidant, anti-inflammatory, and anticancer activities. The compound is provided as a light yellow solid with high purity and is intended for laboratory studies and small-molecule assays.
- Orally active anti-allergic agent and antioxidant.
- Reported anti-inflammatory and anticancer activity for research studies.
- Light yellow solid appearance suitable for handling in laboratory assays.
- High purity (~98.9%) for reproducible experimental results.
- Molecular weight 272.26 g/mol; formula C15H12O5.
- Store sealed away from moisture and light; recommended cold storage conditions for solutions.
Selleck Chemical LLC Hesperidin methylchalcone
Hesperidin methylchalcone is the Citrus original products with powerful antioxidant activity
TARGETMOL CHEMICALS INC CHALCONE 4 HYDRATE 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Chalcone 4 hydrate an anti-parasite compound inhibits the growth of Theileria and Babesia. purity: 98%
Cell Signaling Technology Phospho-Akt Substrate (RXRXXS*/T*) (23C8D2) Rabbit mAb 20 ul
Phospho-Akt Substrate (RXRXXS*/T*) (23C8D2) Rabbit mAb 20 ul
