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Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
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Sodium ferulic (CAS 24276-84-4) is a small molecule inhibitor targeting fibroblast growth factor receptors specifically FGFR1 and FGFR2 It demonstrates inhibitory activity with IC50 values of 3 78 M for FGFR1 and 12 5 M for FGFR2 At the cellular level sodium ferulic suppresses intracellular signaling pathways involved in cell proliferation This compound is utilized in biomedical research to investigate signaling mechanisms and to assess therapeutic potential in disease models such as cancer
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BIBF 1202 (CAS 894783-71-2) is a carboxylate metabolite derivative of BIBF 1120 characterized as a selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2) kinase In biochemical assays BIBF 1202 demonstrates inhibitory activity against VEGFR2 kinase with an IC50 of 62 nM This compound is frequently employed in studies investigating the regulation of the VEGFR2 signaling pathway and its role in endothelial cell function Additionally BIBF 1202 is utilized in preclinical models related to tumor angiogenesis and associated pharmacological research
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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BLU 451 is a central nervous system (CNS)-penetrant wild-type EGFR-sparing covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM It also exhibits a potent anti-tumor efficacy
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p-Coumaric acid (trans-4-hydroxycinnamic acid) analytical standard supplied as a high-purity solid for research and analytical applications. It is intended for use as a reference for identification, quantification, and method validation in chromatographic and spectroscopic workflows.
Analytical standard for identification and quantification
High purity suitable for method validation
Supplied as a 10 mg solid for convenient handling
Compatible with HPLC, GC, and mass spectrometry methods
Useful for calibration and quality control in research laboratories
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