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Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
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4-Methoxycinnamaldehyde is an active constituent of *Agastache rugosa* that shows cytoprotective activity against respiratory syncytial virus (RSV) in human larynx carcinoma cell lines. It effectively inhibits the cytopathic effect of RSV with an estimated IC50 of 0.055 μg/mL.
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2-Benzylideneheptanal (α-amylcinnamaldehyde, CAS 122-40-7) is an aromatic aldehyde supplied as a ready-to-use 10 mM solution in DMSO for laboratory research. It has formula C14H18O, molecular weight 202.29 g/mol, and a reported purity of 99.56%. The solution is intended for in vitro biochemical or ligand screening and is provided with accompanying analytical documentation for handling and quality verification.
Ready-to-use 10 mM solution in DMSO, 1 mL vial.
High reported purity (99.6%).
Chemical identity: 2-benzylideneheptanal (CAS 122-40-7).
Molecular weight 202.29 g/mol; formula C14H18O.
Supplied with SDS, COA, and handling instructions.
Suitable for in vitro biochemical assays and ligand screening.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Cinnamaldehyde is a flavonoid that is naturally synthesized by the shikimate pathway Its supplementation can improve glucose and lipid homeostasis in diabetic animals a TRPA1 agonist
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AMG 487 (S-enantiomer) is the S enantiomer of AMG 487, functioning as an antagonist of the chemokine receptor CXCR3. It is intended for research use only.
Antagonist of chemokine receptor
Available in solid and solution forms
High purity (99.94%)
Off-white to light yellow appearance
Stable for extended periods under proper storage conditions
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AMG 487 S-enantiomer is the S enantiomer of AMG 487, which acts as an antagonist of the chemokine receptor CXCR3. This chemical compound is provided as an off-white to light yellow solid with high purity.
High purity: 99.94%
Antagonist of chemokine receptor CXCR3
Stable as powder at -20°C for 3 years, and 4°C for 2 years
Stable in solvent at -80°C for 2 years, and -20°C for 1 year
Soluble in DMSO at 100 mg/mL
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AST 487 is a potent RET kinase inhibitor with an IC50 of 880 nM, and also demonstrates inhibitory activity against Flt-3 with an IC50 of 520 nM. It effectively inhibits RET autophosphorylation and the activation of downstream effectors, making it suitable for studies on human thyroid cancer cell lines with activating RET mutations.
Inhibits RET kinase (IC50 880 nM)
Inhibits Flt-3 (IC50 520 nM)
Targets other kinases including KDR, Flt-4, c-Kit, and c-Abl
Potently inhibits growth of human thyroid cancer cell lines with activating RET mutations
Functions as a novel, mutant FLT3 inhibitor
Inhibits cellular proliferation in FLT3-ITD-Ba/F3 and D835Y-Ba/F3 cells (IC50 less than 5 nM)
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